2021 revised algorithm for the management of knee osteoarthritis—the Chinese viewpoint

Aim The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) algorithm for the management of knee osteoarthritis (OA) is available worldwide from 2014, but in 2019 an update was published. Based on this algorithm, a Working Group (WG...

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Bibliographic Details
Published in:	Aging clinical and experimental research Vol. 33; no. 8; pp. 2141 - 2147
Main Authors:	Zhang, Zhiyi, Huang, Cibo, Cao, Yongping, Mu, Rong, Zhang, Mun Chan, Xing, Dan, Fan, Dongwei, Ding, Yunpong, Guo, Junhuan, Hou, Yong, Jianhao, Lin, Veronese, Nicola, Reginster, Jean-Yves, Bruyere, Olivier, Cavalier, Etienne, Zhang, Huaihuan
Format:	Journal Article Web Resource
Language:	English
Published:	Cham Springer International Publishing 01-08-2021 Springer Nature B.V Springer
Subjects:	Algorithm Algorithms Arthritis China Clinical medicine Consensus Document Geriatrics/Gerontology Human health sciences Knee Knee osteoartrhitis Laboratory medicine & medical technology Medicine Medicine & Public Health Médecine de laboratoire & technologie médicale Osteoarthritis Patented crystalline glucosamine sulfate Public health, health care sciences & services Santé publique, services médicaux & soins de santé Sciences de la santé humaine Symptomatic slow-acting drugs for osteoarthritis China Knee osteoartrhitis Patented crystalline glucosamine sulfate Symptomatic slow-acting drugs for osteoarthritis Algorithm China
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Summary:	Aim The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) algorithm for the management of knee osteoarthritis (OA) is available worldwide from 2014, but in 2019 an update was published. Based on this algorithm, a Working Group (WG), including ESCEO members and Chinese experts, wished to see how the new ESCEO algorithm was perceived by Chinese experts in knee OA and how it was integrated into their clinical practice. Methods A WG was held between members of the international ESCEO task force and a group of Chinese experts. Results Non-pharmacological approach should be combined with pharmacological interventions. In step 1, symptomatic slow-acting drugs for osteoarthritis (SYSADOA) are the most important background drugs. Evidence, supported by high-quality research, is available only for crystalline glucosamine sulfate (pCGS) and chondroitin sulfate. Topical NSAIDs could be used as an additional option. In step 2, oral NSAIDs could be useful, but cardiovascular/renal/gastrointestinal profiles of the patients should be considered. Intra-articular hyaluronic acid and corticosteroids are alternative to oral NSAIDs, but the evidence is still limited. If steps 1 and 2 are not sufficient, weak opioids could be used . Overall, the conclusions of the ESCEO algorithm are accepted in China for products available in this country. The WG suggests the importance of economic studies, specifically made in China. Conclusion This work provides evidence-based advice to establish a treatment algorithm in knee OA, for practical implementation in clinical practice in China.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 scopus-id:2-s2.0-85109175308
ISSN:	1720-8319 1594-0667 1720-8319
DOI:	10.1007/s40520-021-01906-y