Search Results - "Zhang, Hongbo"

The role of mitochondria in stem cell fate and aging by Zhang, Hongbo, Menzies, Keir J, Auwerx, Johan

“…The importance of mitochondria in energy metabolism, signal transduction and aging in post-mitotic tissues has been well established. Recently, the crucial…”
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Lake volume and groundwater storage variations in Tibetan Plateau's endorheic basin by Zhang, Guoqing, Yao, Tandong, Shum, C. K., Yi, Shuang, Yang, Kun, Xie, Hongjie, Feng, Wei, Bolch, Tobias, Wang, Lei, Behrangi, Ali, Zhang, Hongbo, Wang, Weicai, Xiang, Yang, Yu, Jinyuan

“…The Tibetan Plateau (TP), the highest and largest plateau in the world, with complex and competing cryospheric‐hydrologic‐geodynamic processes, is particularly…”
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Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment by Xu, Xiaoyu, Liu, Chang, Wang, Yonghui, Koivisto, Oliver, Zhou, Junnian, Shu, Yilai, Zhang, Hongbo

“…[Display omitted] CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-associated protein 9) is a potent technology for gene-editing. Owing…”
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Pharmaceutical electrospinning and 3D printing scaffold design for bone regeneration by Wang, Zhen, Wang, Yichuan, Yan, Jiaqi, Zhang, Keshi, Lin, Feng, Xiang, Lei, Deng, Lianfu, Guan, Zhenpeng, Cui, Wenguo, Zhang, Hongbo

“…[Display omitted] Bone regenerative engineering provides a great platform for bone tissue regeneration covering cells, growth factors and other dynamic forces…”
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Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy by Yong, Tuying, Zhang, Xiaoqiong, Bie, Nana, Zhang, Hongbo, Zhang, Xuting, Li, Fuying, Hakeem, Abdul, Hu, Jun, Gan, Lu, Santos, Hélder A., Yang, Xiangliang

“…Developing biomimetic nanoparticles without loss of the integrity of proteins remains a major challenge in cancer chemotherapy. Here, we develop a…”
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Synergistic Effects from Graphene and Carbon Nanotubes Enable Flexible and Robust Electrodes for High-Performance Supercapacitors by Cheng, Yingwen, Lu, Songtao, Zhang, Hongbo, Varanasi, Chakrapani V, Liu, Jie

“…Flexible and lightweight energy storage systems have received tremendous interest recently due to their potential applications in wearable electronics, roll-up…”
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Chang’E-4 initial spectroscopic identification of lunar far-side mantle-derived materials by Li, Chunlai, Liu, Dawei, Liu, Bin, Ren, Xin, Liu, Jianjun, He, Zhiping, Zuo, Wei, Zeng, Xingguo, Xu, Rui, Tan, Xu, Zhang, Xiaoxia, Chen, Wangli, Shu, Rong, Wen, Weibin, Su, Yan, Zhang, Hongbo, Ouyang, Ziyuan

“…Over 60 years of spacecraft exploration has revealed that the Earth’s Moon is characterized by a lunar crust 1 dominated by the mineral plagioclase, overlying…”
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Rare‐Earth Incorporated Alloy Catalysts: Synthesis, Properties, and Applications by Zhang, Shuai, Saji, Sandra Elizabeth, Yin, Zongyou, Zhang, Hongbo, Du, Yaping, Yan, Chun‐Hua

“…To improve the performance of metallic catalysts, alloying provides an efficient methodology to design state‐of‐the‐art materials. As emerging functional…”
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Engineered Extracellular Vesicles for Cancer Therapy by Zhang, Xu, Zhang, Hongbo, Gu, Jianmei, Zhang, Jiayin, Shi, Hui, Qian, Hui, Wang, Dongqing, Xu, Wenrong, Pan, Jianming, Santos, Hélder A.

“…Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of many diseases including cancer. As a result of their natural…”
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Protein acetylation in metabolism — metabolites and cofactors by Menzies, Keir J., Zhang, Hongbo, Katsyuba, Elena, Auwerx, Johan

“…Key Points Acetylation is a key post-translational modification that integrates metabolic flux and physiological processes within cells, including circadian…”
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Programmable and Multifunctional DNA‐Based Materials for Biomedical Applications by Zhang, Yuezhou, Tu, Jing, Wang, Dongqing, Zhu, Haitao, Maity, Sajal Kumar, Qu, Xiangmeng, Bogaert, Bram, Pei, Hao, Zhang, Hongbo

“…DNA encodes the genetic information; recently, it has also become a key player in material science. Given the specific Watson–Crick base‐pairing interactions…”
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Occurrence and hydrogeochemistry of fluoride in alluvial aquifer of Weihe River, China by Li, Peiyue, Qian, Hui, Wu, Jianhua, Chen, Jie, Zhang, Yiqian, Zhang, Hongbo

“…Fluoride (F⁻) has significant impacts on human health. High fluoride groundwater (up to 1.90 mg/L) has been found in upper confined aquifer underlying the…”
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Current developments and applications of microfluidic technology toward clinical translation of nanomedicines by Liu, Dongfei, Zhang, Hongbo, Fontana, Flavia, Hirvonen, Jouni T., Santos, Hélder A.

“…Nanoparticulate drug delivery systems hold great potential for the therapy of many diseases, especially cancer. However, the translation of nanoparticulate…”
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PD-L1-Mediated Immunosuppression in Glioblastoma Is Associated With the Infiltration and M2-Polarization of Tumor-Associated Macrophages by Zhu, Zhiyuan, Zhang, Hongbo, Chen, Baodong, Liu, Xing, Zhang, Shizhong, Zong, Zhitao, Gao, Mengqi

“…There has been no significant improvements for immune checkpoint inhibitors since its first use. Tumour-associated macrophages (TAMs) are critical mediators in…”
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Study of the applicability of Sponge City concepts for flood mitigation based on LID (low impact development) measures: A case study in Conakry City, Republic of Guinea by Bah, Alhassane, Hongbo, Zhang, Bah, Alseny, Jufang, He, Zhumei, Luo

“…Abstract Urban flooding is becoming a significant urban epidemic in many nations throughout the world as a result of land use and climate change, and regular…”
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Current Immunotherapies for Glioblastoma Multiforme by Huang, Boyuan, Li, Xuesong, Li, Yuntao, Zhang, Jin, Zong, Zhitao, Zhang, Hongbo

“…Glioblastoma multiforme (GBM) is the most common and aggressive malignant tumor found in the central nervous system. Currently, standard treatments in the…”
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Dual-functional 3D-printed composite scaffold for inhibiting bacterial infection and promoting bone regeneration in infected bone defect models by Yang, Ying, Chu, Linyang, Yang, Shengbing, Zhang, Hongbo, Qin, Ling, Guillaume, Olivier, Eglin, David, Richards, R. Geoff, Tang, Tingting

“…[Display omitted] Infection is one of the pivotal causes of nonunion in large bone defect after trauma or tumor resection. Three-dimensional (3D) composite…”
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Cells of the adult human heart by Litviňuková, Monika, Talavera-López, Carlos, Maatz, Henrike, Reichart, Daniel, Worth, Catherine L., Lindberg, Eric L., Kanda, Masatoshi, Polanski, Krzysztof, Heinig, Matthias, Lee, Michael, Nadelmann, Emily R., Roberts, Kenny, Tuck, Liz, Fasouli, Eirini S., DeLaughter, Daniel M., McDonough, Barbara, Wakimoto, Hiroko, Gorham, Joshua M., Samari, Sara, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Patone, Giannino, Boyle, Joseph J., Zhang, Hongbo, Zhang, Hao, Viveiros, Anissa, Oudit, Gavin Y., Bayraktar, Omer Ali, Seidman, J. G., Seidman, Christine E., Noseda, Michela, Hubner, Norbert, Teichmann, Sarah A.

“…Cardiovascular disease is the leading cause of death worldwide. Advanced insights into disease mechanisms and therapeutic strategies require a deeper…”
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NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice by Zhang, Hongbo, Ryu, Dongryeol, Wu, Yibo, Gariani, Karim, Wang, Xu, Luan, Peiling, D'Amico, Davide, Ropelle, Eduardo R., Lutolf, Matthias P., Aebersold, Ruedi, Schoonjans, Kristina, Menzies, Keir J., Auwerx, Johan

“…Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to senescence during aging. We demonstrate the importance of…”
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Combined Use of Multiple Cloud‐Free Snow Cover Products in China and Its High‐Mountain Region: Implications From Snow Cover Identification to Snow Phenology Detection by Zhang, Longhui, Zhang, Hongbo, Sun, Xueyan, Luo, Lun

“…Accurate snow phenology detection, including snow cover days (SCD), snow start date (SSD), and snow end date (SED), is increasingly important for understanding…”
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