Search Results - "Zhang, Hong Y"
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Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models
Published in PloS one (26-01-2024)“…Many of the pathological consequences of chronic kidney disease can be attributed to an elevation in serum phosphate levels. Current therapies focused on…”
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2
Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression
Published in The Journal of pharmacology and experimental therapeutics (01-05-2009)“…The mammalian neuropeptide, melanin-concentrating hormone, interacts with two G protein-coupled receptors, melanin-concentrating hormone receptor (MCHR) 1 and…”
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3
Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models
Published in Pharmacology research & perspectives (01-04-2022)“…An excess phosphate burden in renal disease has pathological consequences for bone, kidney, and heart. Therapies to decrease intestinal phosphate absorption…”
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4
Discovery of potent small-molecule inhibitors of lipoprotein(a) formation
Published in Nature (London) (23-05-2024)“…Lipoprotein(a) (Lp(a)), an independent, causal cardiovascular risk factor, is a lipoprotein particle that is formed by the interaction of a low-density…”
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Development of a long‐acting relaxin analogue, LY3540378, for treatment of chronic heart failure
Published in British journal of pharmacology (01-08-2023)“…Background and Purpose Chronic heart failure, a progressive disease with limited treatment options currently available, especially in heart failure with…”
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The Acyl CoenzymeA:Monoacylglycerol Acyltransferase 3 (MGAT3) Gene is a Pseudogene in Mice but Encodes a Functional Enzyme in Rats
Published in Lipids (01-06-2011)“…Triglyceride (TAG) absorption involves its initial hydrolysis to fatty acids and monoacylglycerol (MAG), which are resynthesized back to diacylglycerol (DAG)…”
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Kupffer cell activation by lipopolysaccharide in rats: Role for lipopolysaccharide binding protein and toll‐like receptor 4
Published in Hepatology (Baltimore, Md.) (01-04-2000)“…Lipopolysaccharide (LPS) binding protein (LBP) is a key serum factor that mediates LPS activation of mononuclear cells. In the presence of LBP, 1/1,000 the…”
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Optimization and validation of enzyme-linked immunosorbent assay for the determination of endosulfan residues in food samples
Published in Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes (01-02-2008)“…In this study, an enzyme-linked immunosorbent assay (ELISA) was optimized and applied to the determination of endosulfan residues in 20 different kinds of food…”
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9
Acidosis Impairs the Protective Role of hERG K+ Channels Against Premature Stimulation
Published in Journal of cardiovascular electrophysiology (01-10-2010)“…Acidosis and the hERG K+ Channel. Introduction: Potassium channels encoded by human ether‐à‐go‐go‐related gene (hERG) underlie the cardiac rapid delayed…”
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10
Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models
Published in PloS one (01-01-2024)“…Many of the pathological consequences of chronic kidney disease can be attributed to an elevation in serum phosphate levels. Current therapies focused on…”
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11
Abstract 527: Decay of Hepatic and Serum Apolipoprotein(a) Levels is Slower than ApolipoproteinB Following Inhibition of Lipid Synthesis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2015)“…Abstract only The association of Lipoprotein(a) (Lp(a)) levels and increased cardiovascular risk is substantiated by human epidemiology, genetics and…”
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12
Effects of Estrogen on Thermoregulatory Responses in Freely Moving Female Rats
Published in Annals of the New York Academy of Sciences (01-03-1997)Get full text
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13
Application of Wenner Configuration to Estimate Soil Water Content in Pine Plantations on Sandy Land
Published in Pedosphere (01-12-2007)“…To estimate the mean value of surface soil water content rapidly, accurately, and nonintrusively, field investigations on soil electrical resistivity (SER)…”
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Preparation and performance evaluation of Er203 coating-type selective emitter
Published in 中国科学:技术科学英文版 (2014)“…An Er203 coating-type selective emitter for themophotovoltaic application was prepared by plasma spray technology. The test results show that plasma spray…”
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15
Optimal parity vector sensitive to designated sensor fault
Published in IEEE transactions on aerospace and electronic systems (01-10-1999)“…Based on the parity space construction and the orthogonal constraint condition of parity vector, the approach of fault detection and isolation using optimal…”
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16
Knockdown of yes-associated protein inhibits proliferation and downregulates large tumor suppressor 1 expression in MHCC97H human hepatocellular carcinoma cells
Published in Molecular medicine reports (01-06-2015)“…The pathogenesis of hepatocellular carcinoma (HCC) is thought to involve the interaction of numerous genes. Identification of these genes and proteins which…”
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17
Super Resolution Reconstruction Method of Solar Panel Defect Images Based on Meta-transfer
Published in Ji suan ji ke xue (01-03-2022)“…It is difficult to detect solar panel crack defect due to low resolution and contrast, and few samples lead to inadequate training problem.To solve these…”
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The relationship between renal function and risk factors of cardiovascular disease in Chinese rural elderly population
Published in International journal of cardiology (01-10-2009)Get full text
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A survey of hypertension, diabetes and dyslipidemia in a village residence in Beijing suburb
Published in International journal of cardiology (01-10-2009)Get full text
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Distinct roles of Akt1 in regulating proliferation, migration and invasion in HepG2 and HCT 116 cells
Published in Oncology reports (01-02-2014)“…Elucidating the effects of genes involved in tumors may improve therapeutic strategies for human cancer. Recently, several studies discovered that Akt1 plays a…”
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