Search Results - "Zhang, Furen"
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1
High Expression of ACE2 on Keratinocytes Reveals Skin as a Potential Target for SARS-CoV-2
Published in Journal of investigative dermatology (01-01-2021)Get full text
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2
COVID‐19 and cutaneous manifestations: a systematic review
Published in Journal of the European Academy of Dermatology and Venereology (01-11-2020)“…The cutaneous manifestations of COVID‐19 patients have been increasingly reported, but not summarized, and the potential mechanisms remain to be investigated…”
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Advances in the Immunology and Genetics of Leprosy
Published in Frontiers in immunology (16-04-2020)“…Leprosy, a disease caused by the intracellular parasite or , has affected humans for more than 4,000 years and is a stigmatized disease even now. Since…”
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4
Recurrent Leg Ulcer, Underweight, Short Stature, and Exocrine Pancreatic Insufficiency
Published in The American journal of gastroenterology (01-08-2020)Get full text
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5
The burden of skin diseases in China: global burden of Disease Study 2019
Published in Archives of dermatological research (25-05-2024)“…Skin diseases continue to affect human health and cause a significant disease burden on the healthcare system.We aimed to report the changing trends in the…”
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Prevalence of genital Chlamydia trachomatis infection in the general population: a meta-analysis
Published in BMC infectious diseases (08-08-2020)“…Abstract Background Estimating prevalence of Chlamydia trachomatis (CT) worldwide is necessary in designing control programs and allocating health resources…”
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7
Dapsone hypersensitivity syndrome
Published in Chinese medical journal (05-07-2023)“…HLA-B∗13:01 has been found to be a strong risk factor for DHS, according to a genome-wide association study (odds ratio, 20.53; P = 6.84 × 10−25)[5] and major…”
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Comprehensive measures succeeded in improving early detection of leprosy cases in post-elimination era: Experience from Shandong province, China
Published in PLoS neglected tropical diseases (01-02-2020)“…A few new leprosy cases still can be seen in Shandong province after elimination. In post-elimination era, government commitments dwindled and active…”
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Efficacy and safety of CM310 in moderate-to-severe atopic dermatitis: A multicenter, randomized, double-blind, placebo-controlled phase 2b trial
Published in Chinese medical journal (20-01-2024)“…Atopic dermatitis (AD) affects approximately 10% of adults worldwide. CM310 is a humanized monoclonal antibody targeting interleukin-4 receptor alpha that…”
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10
Biologics-induced immunophenotypic cross-switching in patients with psoriasis and atopic dermatitis
Published in Indian journal of dermatology (01-03-2023)“…Antibody-based therapies that inhibit pro-inflammatory cytokine signalling are commonly used in dermatology. Paradoxically, these biological agents may induce…”
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11
Genetic Structure of the Han Chinese Population Revealed by Genome-wide SNP Variation
Published in American journal of human genetics (11-12-2009)“…Population stratification is a potential problem for genome-wide association studies (GWAS), confounding results and causing spurious associations. Hence,…”
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12
Development and evaluation of a rapid diagnostic method for Sporothrix globosa in Asia using quantitative real-time PCR
Published in BMC infectious diseases (14-08-2024)“…Sporotrichosis is a chronic granulomatous infection of the skin and subcutaneous tissue that can affect any organ through lymphatic spread. The prevalence of…”
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13
Single-cell transcriptomics analysis of bullous pemphigoid unveils immune-stromal crosstalk in type 2 inflammatory disease
Published in Nature communications (15-07-2024)“…Bullous pemphigoid (BP) is a type 2 inflammation- and immunity-driven skin disease, yet a comprehensive understanding of the immune landscape, particularly…”
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14
Single-cell sequencing analysis reveals development and differentiation trajectory of Schwann cells manipulated by M. leprae
Published in PLoS neglected tropical diseases (01-07-2023)“…M. leprae preferentially infects Schwann cells (SCs) in the peripheral nerves leading to nerve damage and irreversible disability. Knowledge of how M. leprae…”
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A multi-center, double-blind, randomized, placebo- and positive-controlled phase II clinical study of benvitimod for the treatment of atopic dermatitis
Published in Chinese medical journal (20-01-2023)“…[4] This multi-center, randomized, double-blinded, placebo-, and positive-controlled phase II clinical trial was approved by the Ethics Committee of People's…”
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16
COVID-19 exacerbates psoriasis progression through inducing IFN-α expression
Published in Asian Pacific journal of tropical medicine (01-08-2024)Get full text
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17
Tildrakizumab for moderate-to-severe plaque psoriasis in Chinese patients: A 12-week randomized placebo-controlled phase III trial with long-term extension
Published in Chinese medical journal (20-05-2024)“…There is a need for effective and safe therapies for psoriasis that provide sustained benefits. The aim of this study was to assess the efficacy and safety of…”
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Analysis of the autoimmune response to BP180 in Chinese stroke patients
Published in Anais brasileiros de dermatología (01-01-2023)“…Significant association between bullous pemphigoid (BP) and stroke has been reported. This study aimed to evaluate the level of anti-BP180 antibody in stroke…”
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19
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy
Published in Nature genetics (01-03-2015)“…Furen Zhang and colleagues report the results of a three-stage genome-wide association study of leprosy in the Chinese population. They discover six new…”
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Loss-of-function mutations in Keratin 32 gene disrupt skin immune homeostasis in pityriasis rubra pilaris
Published in Nature communications (24-07-2024)“…Pityriasis rubra pilaris (PRP) is an inflammatory papulosquamous dermatosis, characterized by hyperkeratotic follicular papules and erythematous desquamative…”
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