Search Results - "Zhang, Chujing"
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Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-06-2021)“…Aldehyde dehydrogenases (ALDHs) are overexpressed in various types of cancers. One of the ALDH family genes, ALDH1A2, is aberrantly expressed in more than 50%…”
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ISL1 regulates lung branching morphogenesis via Shh signaling pathway
Published in The Journal of biological chemistry (01-08-2023)“…Lung branching morphogenesis relies on a complex coordination of multiple signaling pathways and transcription factors. Here, we found that ablation of the LIM…”
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Targeting M2-Tumor Associated Macrophages By Arginase-1 and PD-L1 in Regulating Juvenile Myelomonocytic Leukemia (JMML) Development and Relapse
Published in Blood (23-11-2021)“…Tumor-associated macrophages (TAMs) are a key component of tumor-infiltrating immune cells. Macrophages are largely characterized as M1 or M2 types, and TAMs…”
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MEK Inhibition Demonstrates Activity in Relapsed, Refractory Patients with Juvenile Myelomonocytic Leukemia: Results from COG Study ADVL1521
Published in Blood (23-11-2021)“…▪ Background: Juvenile myelomonocytic leukemia (JMML) is a hematologic malignancy of infants and toddlers with both myelodysplastic and myeloproliferative…”
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Oncogenic transcriptional program driven by TAL1 in T-cell acute lymphoblastic leukemia
Published in International journal of hematology (01-01-2019)“…TAL1 / SCL is a prime example of an oncogenic transcription factor that is abnormally expressed in acute leukemia due to the replacement of regulator elements…”
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Induction of right open reading frame kinase 3 (RIOK3) during ovulation and luteinisation in rat ovary
Published in Reproduction fertility and development (01-11-2021)“…Atypical protein serine kinase RIOK3 is involved in cellular invasion and survival. The spatiotemporal expression pattern and regulatory mechanisms controlling…”
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Inhibition of BTK and PI3Kδ impairs the development of human JMML stem and progenitor cells
Published in Molecular therapy (06-07-2022)“…Juvenile myelomonocytic leukemia (JMML) is an aggressive myeloproliferative neoplasia that lacks effective targeted chemotherapies. Clinically, JMML manifests…”
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Abstract LB-301: Oncorequisite role of an aldehyde dehydrogenase in the pathogenesis of T-cell acute lymphoblastic leukemia
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Aldehyde dehydrogenases (ALDHs) have been implicated as a stem cell marker both in normal and malignant cells. Elevated ALDH activity is associated with the…”
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Visualization Analysis and XGBoost-Based Prediction of COVID-19 Mortality
Published in 2023 IEEE International Conference on Image Processing and Computer Applications (ICIPCA) (11-08-2023)“…For the best predictive results of novel coronavirus infection and COVID-19 mortality, this research bases on the XGBoost machine learning algorithm. Through…”
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