Search Results - "Zhang, Can Martin"

An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo by Zhang, Xulun, Zhang, Can Martin, Prokopenko, Dmitry, Liang, Yingxia, Zhen, Sherri Y, Weigle, Ian Q, Han, Weinong, Aryal, Manish, Tanzi, Rudolph E, Sisodia, Sangram S

“…Familial Alzheimer's disease (FAD)-linked mutations in the APP gene occur either within the Aβ-coding region or immediately proximal and are located in exons…”
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Gut microbiota-driven brain Aβ amyloidosis in mice requires microglia by Dodiya, Hemraj B, Lutz, Holly L, Weigle, Ian Q, Patel, Priyam, Michalkiewicz, Julia, Roman-Santiago, Carlos J, Zhang, Can Martin, Liang, Yingxia, Srinath, Abhinav, Zhang, Xulun, Xia, Jessica, Olszewski, Monica, Zhang, Xiaoqiong, Schipma, Matthew John, Chang, Eugene B, Tanzi, Rudolph E, Gilbert, Jack A, Sisodia, Sangram S

“…We previously demonstrated that lifelong antibiotic (ABX) perturbations of the gut microbiome in male APPPS1-21 mice lead to reductions in amyloid β (Aβ)…”
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