Search Results - "Zhan, Zhajun"

Comprehensive Mapping of Cyclotides from Viola philippica by Using Mass Spectrometry-Based Strategy by Yu, Liyan, Pan, Hailiang, Chen, Xiaohang, Gong, Shan, Zhang, Qipeng, Zhang, Yandong, Zhan, Zhajun

“…Cyclotides are plant cyclic peptides with exceptional stability and diverse bioactivity, making them promising candidates for biomedical applications…”
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Purification, Structural Analysis and Cardio-Protective Activity of Polysaccharides from Radix Astragali by Wang, Shilei, Peng, Yuan, Zhuang, Yixin, Wang, Nan, Jin, Jianchang, Zhan, Zhajun

“…Two polysaccharides, named APS2-I and APS3-I, were purified from the water extract of Radix Astragali. The average molecular weight of APS2-I was 1.96 × 10 Da…”
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Tandem Prenyltransferases Catalyze Isoprenoid Elongation and Complexity Generation in Biosynthesis of Quinolone Alkaloids by Zou, Yi, Zhan, Zhajun, Li, Dehai, Tang, Mancheng, Cacho, Ralph A, Watanabe, Kenji, Tang, Yi

“…Modification of natural products with prenyl groups and the ensuing oxidative transformations are important for introducing structural complexity and…”
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Cost-effectiveness analysis of rezvilutamide versus bicalutamide in the treatment of metastatic hormone-sensitive prostate cancer by Ding, Haiying, Li, Shujing, Xu, Xinglu, Xu, Weiben, He, Chaoneng, Xin, Wenxiu, Zhan, ZhaJun, Fang, Luo

“…ObjectivesThe economic implications of combining rezvilutamide with androgen deprivation therapy (ADT) remain uncertain, despite the observed survival…”
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Preparation and study of two kinds of ophthalmic nano-preparations of everolimus by Tang, Zhan, Yin, Lina, Zhang, Yawen, Yu, Wenying, Wang, Qiao, Zhan, Zhajun

“…Objective: To prepare everolimus nanoformulations and increase their solubility to suit their application in the eye. Methods: The everolimus micelles was…”
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15,16-dihydrotanshinone I Induces Apoptosis and Inhibits the Proliferation, Migration of Human Osteosarcoma Cell Line 143B in vitro by Chen, Xuepeng, Li, Qihong, He, Yan, Du, Hongjiang, Zhan, Zhajun, Zhao, Hong, Shi, Jiejun, Ye, Qingsong, Hu, Ji'an

“…15,16-dihydrotanshinone I (DHTI), a lipophilic tanshinone extracted from Danshen root (Salvia miltiorrhiza Bunge), has been reported to function as an…”
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α-Glucosidase and Bacterial β-Glucuronidase Inhibitors from the Stems of Schisandra sphaerandra Staph by Rao, Guiwei, Yu, Hangfei, Zhang, Manlai, Cheng, Yuchen, Ran, Kun, Wang, Jianwei, Wei, Bin, Li, Min, Shan, Weiguang, Zhan, Zhajun, Ying, Youmin

“…α-Glucosidase (AGS) is a therapeutic target for Type 2 diabetes mellitus (T2DM) that tends to complicate with other diseases. Some medications for the…”
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Activation of an unconventional meroterpenoid gene cluster in Neosartorya glabra leads to the production of new berkeleyacetals by Zhang, Tao, Wan, Jun, Zhan, Zhajun, Bai, Jian, Liu, Bingyu, Hu, Youcai

“…Fungal genomes carry many gene clusters seemingly capable of natural products biosynthesis, yet most clusters remain cryptic or down-regulated. Genome mining…”
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Electrochemical Reductive Cross-Coupling of Alkyl or Alkenyl Halides with gem-Difluoroalkenes by Zhang, Hong, Ye, Zenghui, Tang, Jiyuan, Wu, Yanqi, Zhang, Xi, Ma, Weiyuan, Zhan, Zhajun, Zhang, Fengzhi

“…Herein, we describe an electroreductive cross-electrophile coupling protocol for the construction of valuable monofluoroalkenes from easily accessible alkyl or…”
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Multi_CycGT: A Deep Learning-Based Multimodal Model for Predicting the Membrane Permeability of Cyclic Peptides by Cao, Lujing, Xu, Zhenyu, Shang, Tianfeng, Zhang, Chengyun, Wu, Xinyi, Wu, Yejian, Zhai, Silong, Zhan, Zhajun, Duan, Hongliang

“…Cyclic peptides are gaining attention for their strong binding affinity, low toxicity, and ability to target “undruggable” proteins; however, their therapeutic…”
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Dual C(sp3)–H Functionalization of Cyclic Ethers via Singlet Oxygen-Mediated Ring Opening and Ring Closing by Yuan, Xu, Yu, Xianglin, He, Kun, Zhang, Ruihan, Xiao, Weilie, Lin, Jun, Zhan, Zhajun, Cheng, Xiaohong, Shao, Zhihui, Jin, Yi

“…A metal-free dual C­(sp3)–H bond functionalization of saturated cyclic ethers via photooxidative singlet oxygen-mediated ring opening and ring closing has been…”
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Ullmann-type C–N coupling reaction catalyzed by CuI/metformin by Zhang, Chao, Zhan, Zhajun, Lei, Min, Hu, Lihong

“…A facile and efficient method for Ullmann-type C–N coupling reaction of amine and aryl halide catalyzed by CuI/metformin in EtOH is described. The advantages…”
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Aurovertin B exerts potent antitumor activity against triple-negative breast cancer in vivo and in vitro via regulating ATP synthase activity and DUSP1 expression by Wu, Rui, Yang, Xi, Zhou, Qian, Yu, Wenyan, Li, Minwei, Wo, Jianer, Shan, Weiguang, Zhao, Hong, Chen, Yan, Zhan, Zhajun

“…Aurovertin B, a natural compound from , exhibits potent antiproliferative activity particularly against triple-negative breast cancer cells (TNBC), while…”
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Highly anticipated natural diterpenoids as an important source of new drugs in 2013–2023 by Wang, Yingjie, Tang, Peng, Tu, Wenchao, Gao, Qi, Wang, Cuizhu, Tan, Luying, Zhao, Lixin, Han, Hongye, Ma, Liefeng, Otsuki, Kouharu, Xiao, Weilie, Wang, Wenli, Liu, Jinping, Li, Yong, Zhan, Zhajun, Li, Wei, Zhou, Xianli, Li, Ning

“…This review covers the structures of diterpenoids, including chain (72), monocyclic (9), labdane-type (67), clerodane-type (127) abietane-type (716),…”
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Identification and analysis of the gene cluster involved in biosynthesis of paenibactin, a catecholate siderophore produced by Paenibacillus elgii B69 by Wen, Yanping, Wu, Xuechang, Teng, Yi, Qian, Chaodong, Zhan, Zhajun, Zhao, Yuhua, Li, Ou

“…Summary Bacteria belonging to the genus Paenibacillus are recognized as rich sources of bioactive natural products. To date, there are few characterized…”
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HPLC–MS/MS-Based Analysis of Everolimus in Rabbit Aqueous Humor: Pharmacokinetics of in Situ Gel Eye Drops of Suspension by Tang, Zhan, Wang, Ling, Xia, Zhifang, Shi, Ming, Wang, Qiao, Zhan, Zhajun

“…Aim: Everolimus is an inhibitor of mTOR which is derived from rapamycin. Its high corneal permeability and bioavailability makes it an effective treatment for…”
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A green, efficient, and rapid procedure for the hydrogenation of nitroarenes to formanilides in water by Wang, Yingying, Zhan, Zhajun, Zhou, Yang, Lei, Min, Hu, Lihong

“…A green, efficient, and rapid procedure for the hydrogenation of nitroarenes to formanilides in Pd(TFA) 2 /HCOOH system in water is described. Under optimized…”
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C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways by Zhang, Yu, Li, Kaiqiang, Ying, Youmin, Chen, Bingyu, Hao, Ke, Chen, Boxu, Zheng, Yu, Lyu, Jianxin, Tong, Xiangming, Chen, Xiaopan, Wang, Ying, Zhan, Zhajun, Zhang, Wei, Wang, Zhen

“…extraction (MTE), a traditional herbal medicine, has exhibited anti-tumor effects on a variety of cancers. However, its effectiveness and the mechanism of…”
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Structurally Diverse Sesquiterpenoids from the Genus of Ainsliaea by Zhan, Zhajun, Zhuang, Yi-Xin, Wang, Shu-Xuan, Luo, Shan-Rong, Ma, Lie-Feng

“…The genus of Ainsliaea embraces approximately 70 recognized species, many of which have been used to treat various diseases in folklore medicines. As the main…”
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HPLC-MS/MS-based analysis of everolimus in rabbit aqueous humor: pharmacokinetics of by Tang, Zhan, Wang, Ling, Xia, Zhifang, Shi, Ming, Wang, Qiao, Zhan, Zhajun

“…Everolimus is an inhibitor of mTOR which is derived from rapamycin. Its high corneal permeability and bioavailability makes it an effective treatment for…”
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