Search Results - "Zhan, Yujuan"

Hederagenin potentiated cisplatin- and paclitaxel-mediated cytotoxicity by impairing autophagy in lung cancer cells by Wang, Kun, Liu, Xiaodong, Liu, Quanmeng, Ho, Idy ht, Wei, Xianli, Yin, Ting, Zhan, Yujuan, Zhang, Wenjing, Zhang, Wenbo, Chen, Bonan, Gu, Jiangyong, Tan, Yuhui, Zhang, Lin, Chan, Matthew Tv, Wu, William Kk, Du, Biaoyan, Xiao, Jianyong

“…Autophagy inhibition has been demonstrated to increase the efficacy of conventional chemotherapy. In this study, we identified hederagenin, a triterpenoid…”
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Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria by Wang, Kun, Zhan, Yujuan, Chen, Bonan, Lu, Yuhua, Yin, Ting, Zhou, Shikun, Zhang, Weibin, Liu, Xiaodong, Du, Biaoyan, Wei, Xianli, Xiao, Jianyong

“…Cancer cells have developed chemoresistance and have improved their survival through the upregulation of autophagic mechanisms that protect mitochondrial…”
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Sensitive Identification of Microcystin-LR via a Reagent-Free and Reusable Electrochemical Biosensor Using a Methylene Blue-Labeled Aptamer by Wei, Xiaoqian, Wang, Shanlin, Zhan, Yujuan, Kai, Tianhan, Ding, Ping

“…We report a methylene blue (MB)-modified electrochemical aptamer (E-AB) sensor for determining microcystin-LR (MC-LR). The signal transduction of the sensor…”
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Dioscin potentiates the antitumor effect of suicide gene therapy in melanoma by gap junction intercellular communication-mediated antigen cross-presentation by Zhang, Wenbo, Lin, Lingyun, Zhang, Yujian, Zhao, Tingxiu, Zhan, Yujuan, Wang, Huiqi, Fang, Junfeng, Du, Biaoyan

“…Dioscin (Dio), steroid saponin, exists in several medicinal herbs with potent anticancer efficacy. This study aimed to explore the effect of Dio on the…”
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Dioscin Inhibits the Invasion and Migration of Hepatocellular Carcinoma HepG2 Cells by Reversing TGF-β1-Induced Epithelial-Mesenchymal Transition by Chen, Bonan, Zhou, Shikun, Zhan, Yujuan, Ke, Junzi, Wang, Kun, Liang, Qiqi, Hou, Yu, Zhu, Pingping, Ao, Weizhen, Wei, Xianli, Xiao, Jianyong

“…Dioscin is a natural steroidal saponin that can be isolated from Chinese medicine, such as Dioscoreae rhizoma. It has wild range of pharmacological activities…”
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Aptamer-AuNP-conjugated carboxymethyl chitosan–functionalized graphene oxide for colorimetric identification of Salmonella typhimurium by Wu, Pian, Huang, Ruixue, Chen, Cuimei, Yi, Jiecan, Kai, Tianhan, Zhan, Yujuan, Wei, Xiaoqian, Wang, Danqi, Zhang, Jingwen, Ding, Ping

“…A novel aptamer-AuNP-conjugated carboxymethyl chitosan–functionalized graphene oxide (CMC/GO@Apt-Au NP) probe was for the first time developed for the…”
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The Novel Autophagy Inhibitor Alpha-Hederin Promoted Paclitaxel Cytotoxicity by Increasing Reactive Oxygen Species Accumulation in Non-Small Cell Lung Cancer Cells by Zhan, Yujuan, Wang, Kun, Li, Qiao, Zou, Yidan, Chen, Bonan, Gong, Qing, Ho, Hiuting Idy, Yin, Ting, Zhang, Fangyuan, Lu, Yuhua, Wu, Weijie, Zhang, Yilin, Tan, Yuhui, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong

“…Chemoresistance is a major limiting factor that impairs the outcome of non-small cell lung cancer (NSCLC) chemotherapy. Paclitaxel (Tax) induces protective…”
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N -Methylparoxetine Blocked Autophagic Flux and Induced Apoptosis by Activating ROS-MAPK Pathway in Non-Small Cell Lung Cancer Cells by Wang, Kun, Chen, Bonan, Yin, Ting, Zhan, Yujuan, Lu, Yuhua, Zhang, Yilin, Chen, Jiawei, Wu, Weijie, Zhou, Shikun, Mao, Wenli, Tan, Yuhui, Du, Biaoyan, Liu, Xiaodong, Ho, Hiuting Idy, Xiao, Jianyong

“…The main mechanistic function of most chemotherapeutic drugs is mediated by inducing mitochondria-dependent apoptosis. Tumor cells usually respond to…”
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AICD: an integrated anti-inflammatory compounds database for drug discovery by Wang, Kun, Xiao, Jianyong, Liu, Xiaodong, Jiang, Zhuqiao, Zhan, Yujuan, Yin, Ting, He, Lina, Zhang, Fangyuan, Xing, Shangping, Chen, Bonan, Li, Yingshi, Zhang, Fengxue, Kuang, Zaoyuan, Du, Biaoyan, Gu, Jiangyong

“…Systemic or local inflammation drives the pathogenesis of various human diseases. Small compounds with anti-inflammatory properties hold great potential for…”
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Recent advances in immunoassay technologies for the detection of human coronavirus infections by Wang, Danqi, Chen, Yuejun, Xiang, Shan, Hu, Huiting, Zhan, Yujuan, Yu, Ying, Zhang, Jingwen, Wu, Pian, Liu, Fei Yue, Kai, Tianhan, Ding, Ping

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the seventh coronavirus (CoV) that has spread in humans and has become a global pandemic since…”
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Pharmacokinetics and metabolomics of the new psychoactive substance 4-chloroethylcathinone by Wang, Yong, Yang, Ying, Zhan, Yujuan, Yin, Jun, Zhou, Xueting, Xu, Chen, Gao, Feiyu, Liu, Junning, Wu, Chunyong, Liu, Songqin, Zhang, Junying, Shu, Chang

“…Synthetic 4-Chloroethcathinone (4-CEC) is a derivative of cathinone that belongs to one of the more severe abused substances among new psychoactive substances…”
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Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway by Wang, Kun, Gong, Qing, Zhan, Yujuan, Chen, Bonan, Yin, Ting, Lu, Yuhua, Zhang, Yilin, Wang, Huiqi, Ke, Junzi, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong

“…Cancer cells are characterized by malignant proliferation and aberrant metabolism and are thereby liable to the depletion of nutrients and accumulation of…”
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Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells by Yi, Hua, Wang, Kun, Du, Biaoyan, He, Lina, Ho, Hiuting, Qiu, Maosong, Zou, Yidan, Li, Qiao, Jin, Junfeng, Zhan, Yujuan, Zhao, Zhongxiang, Liu, Xiaodong

“…Aleuritolic acid (AA) is a triterpene that is isolated from the root of Geisel. In the present study, the cytotoxic effects of AA on hepatocellular carcinoma…”
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Screening and Identification of Potential Biomarkers for Hepatocellular Carcinoma: An Analysis of TCGA Database and Clinical Validation by Wei, Xianli, Ke, Junzi, Huang, Haonan, Zhou, Shikun, Guo, Ao, Wang, Kun, Zhan, Yujuan, Mai, Cong, Ao, Weizhen, Xie, Fuda, Luo, Rongping, Xiao, Jianyong, Wei, Hang, Chen, Bonan

“…Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Up to now, many genes associated with HCC have not yet been identified. In this…”
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Therapeutic strategies for drug‐resistant Pseudomonas aeruginosa: Metal and metal oxide nanoparticles by Zhan, Yujuan, Hu, Huiting, Yu, Ying, Chen, Cuimei, Zhang, Jingwen, Jarnda, Kermue Vasco, Ding, Ping

“…Pseudomonas aeruginosa (PA) is a widely prevalent opportunistic pathogen. Multiple resistant strains of PA have emerged from excessive or inappropriate use of…”
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Development of an Ultrasensitive Competitive Double-Enzyme Cascade Fluorescence Signal Amplification Method for Factor XIa Inhibitor Screening by Zhan, Yujuan, Bao, Xingyan, Hu, Penghui, Ning, Jiangyue, Yan, Zelong, Chen, Haotian, Ding, Ya, Ding, Li, Shu, Chang

“…Coagulation factor XIa (FXIa) is associated with a low risk of bleeding and has been identified as an effective and safe target for the development of novel…”
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A sensitive analytical strategy of oligonucleotide functionalized fluorescent probes for detection of nusinersen sodium in human serum by Zhan, Yujuan, Guo, Jingru, Hu, Penghui, Huang, Ruiyan, Ning, Jiangyue, Bao, Xingyan, Chen, Haotian, Yan, Zelong, Ding, Li, Shu, Chang

“…Spinal muscular atrophy (SMA) is a rare autosomal recessive neuromuscular disease. Nusinersen sodium (NS) is the world's first antisense oligonucleotide (ASO)…”
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Identification of Fangchinoline as a novel autophagy inhibitor with an adjuvant of chemotherapy against lung cancer by Ren, Zhenyang, Song, Yue, Xian, Jinhuan, Liao, Yuan, Zhan, Yujuan, Zhao, Tingxiu, Wang, Huiqi, Jiang, Junbo, Xu, Mansi, Jiang, Yanjun, Liu, Xiaodong, Wei, Xianli, Wang, Kun, Xiao, Jianyong

“…Autophagy is a fundamental recycling pathway that enhances cellular resilience, promoting survival. However, this survival mechanism can impede anti-cancer…”
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Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway by Chen, Bonan, Song, Yue, Zhan, Yujuan, Zhou, Shikun, Ke, Junzi, Ao, Weizhen, Zhang, Yigan, Liang, Qiqi, He, Minhui, Li, Shuhui, Xie, Fuda, Huang, Haonan, Chan, Wai Nok, Cheung, Alvin H.K., Ma, Brigette B.Y., Kang, Wei, To, Ka Fai, Xiao, Jianyong

“…Few drugs alleviate non-small cell lung cancer (NSCLC) metastasis effectively. Small molecular screening demonstrated that fangchinoline (Fan) reversed…”
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Berbamine Hydrochloride inhibits lysosomal acidification by activating Nox2 to potentiate chemotherapy-induced apoptosis via the ROS-MAPK pathway in human lung carcinoma cells by Zhan, Yujuan, Chen, Qiugu, Song, Yue, Wei, Xianli, Zhao, Tingxiu, Chen, Bonan, Li, Chengxi, Zhang, Wenbo, Jiang, Yanjun, Tan, Yuhui, Du, Biaoyan, Xiao, Jianyong, Wang, Kun

“…Autophagy is typically activated in cancer cells as a rescue strategy in response to cellular stress (e.g., chemotherapy). Herein, we found that Berbamine…”
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