Search Results - "Zhan, Yan"
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ULK1 phosphorylates Exo70 to suppress breast cancer metastasis
Published in Nature communications (08-01-2020)“…Increased expression of protein kinase ULK1 was reported to negatively correlate with breast cancer metastasis. Here we report that ULK1 suppresses the…”
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2
The 2017 Jiuzhaigou Earthquake: A Complicated Event Occurred in a Young Fault System
Published in Geophysical research letters (16-03-2018)“…The Minshan Uplift Zone (MUZ) is located at the eastern margin of the Tibetan Plateau, which is the junction of three tectonic terranes. The observed…”
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3
Gap junctions mediate glucose transfer to promote colon cancer growth in three-dimensional spheroid culture
Published in Cancer letters (10-04-2022)“…In vivo tumor growth is characterized by a necrotic core generated by oxygen and nutrients gradients, which is replicated by in vitro three-dimensional (3D)…”
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4
NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
Published in Molecular cell (05-10-2017)“…Many infections and stress signals can rapidly activate the NLRP3 inflammasome to elicit robust inflammatory responses. This activation requires a priming…”
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5
Berberine decelerates glucose metabolism via suppression of mTOR‑dependent HIF‑1α protein synthesis in colon cancer cells
Published in Oncology reports (01-05-2018)“…Hyperactivated glucose uptake and glycolytic metabolism are considered as a hallmark of cancer. Berberine, a natural alkaloid with tumor‑selective anticancer…”
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6
Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
Published in Cell (07-03-2019)“…The presence of DNA in the cytoplasm is normally a sign of microbial infections and is quickly detected by cyclic GMP-AMP synthase (cGAS) to elicit…”
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7
Near Work Related Parameters and Myopia in Chinese Children: the Anyang Childhood Eye Study
Published in PloS one (05-08-2015)“…To examine the associations of near work related parameters with spherical equivalent refraction and axial length in Chinese children. A total of 1770 grade 7…”
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New Magnetotelluric Data Reveal Deep Fault Boundaries and Contrasting Late Cenozoic Fault Kinematics Between the Qilian Shan Thrust Wedge and Beishan‐Alxa Block, Western China
Published in Geophysical research letters (16-03-2024)“…The structural connectivity and kinematic relationship between the Altyn Tagh sinistral strike‐slip fault (ATF) and Qilian Shan fold‐and‐thrust belt along the…”
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9
High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer
Published in Molecular cancer (17-11-2018)“…Tob1, a Tob/BTG anti-proliferative protein family member, functions as a tumour suppressor in many cancers. Here, we reveal a unique oncogenic role of Tob1 in…”
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10
A Fast Non‐Local Means Filtering Method for Interferometric Phase Based on Wavelet Packet Transform
Published in Radio science (01-06-2021)“…Phase unwrapping is very important to acquire surface deformation using InSAR, unwrapping the interferometric phase directly is not appropriate because the…”
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11
Some fluorine-containing and sulfur-containing functional new reagents
Published in Synthetic communications (01-11-2024)“…The research and development of new reagents play a crucial role for organic synthesis. In recent years, numerous new reagents with universal applicability…”
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12
A comparison between three-dimensional, transient, thermomechanically coupled first-order and Stokes ice flow models
Published in Journal of glaciology (01-06-2023)“…In this study, we investigate the differences between two transient, three-dimensional, thermomechanically coupled ice-sheet models, namely, a first-order…”
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13
Does a Shallow Magma Reservoir Exist in the Wudalianchi Volcanic Field? Constraints From Magnetotelluric Imaging
Published in Geophysical research letters (16-09-2023)“…We obtain new images of the 3D resistivity structure of the Wudalianchi volcanic field (WVF). No low‐resistivity structure is found beneath Laoheishan and…”
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14
Rapid and longer-term antidepressant effects of repeated-dose intravenous ketamine for patients with unipolar and bipolar depression
Published in Journal of psychiatric research (01-11-2018)“…Single-dose intravenous (IV) injection of ketamine has shown rapid but transient antidepressant effects. The strategy of repeated-dose ketamine infusions to…”
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15
Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α
Published in Frontiers in pharmacology (28-11-2019)“…The Warburg effect is a peculiar feature of cancer's metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal…”
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16
Development and validation of a nomogram to estimate fatigue probability in hemodialysis patients
Published in Renal failure (01-12-2024)“…This study aims to investigate the factors that influence fatigue in hemodialysis (HD) patients and to develop and validate a nomogram to estimate the…”
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17
Studies of the Efficacy of Low-Dose Apatinib Monotherapy as Third-Line Treatment in Patients with Metastatic Colorectal Cancer and Apatinib's Novel Anticancer Effect by Inhibiting Tumor-Derived Exosome Secretion
Published in Cancers (19-05-2022)“…Antiangiogenic therapy is an important treatment strategy for metastatic colorectal cancer (mCRC). We carried out a clinical study of low-dose apatinib (250…”
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18
Exo70 is an independent prognostic factor in colon cancer
Published in Scientific reports (11-07-2017)“…Exo70, a key component of the Exocyst complex, plays important roles in human cancer progression beyond exocytosis. However, the expression of Exo70 and its…”
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19
A novel and alternative therapy for persistent allergic rhinitis via intranasal acupuncture: a randomized controlled trial
Published in European archives of oto-rhino-laryngology (01-06-2023)“…Background Acupuncture is used to treat allergic rhinitis (AR) in traditional Chinese medicine, and the ST2 and ST36 acupoints are generally selected in…”
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20
Analyzing EFL learners’ demotivating factors in blended learning context
Published in Frontiers in psychology (20-10-2023)“…In second language and foreign language learning, demotivation in learning is a common occurrence. Almost all previous studies on learners’ demotivation…”
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