Search Results - "Zhan, Xiaoguo"

Monoclonal antibody therapy for Junin virus infection by Zeitlin, Larry, Geisbert, Joan B., Deer, Daniel J., Fenton, Karla A., Bohorov, Ognian, Bohorova, Natasha, Goodman, Charles, Kim, Do, Hiatt, Andrew, Pauly, Michael H., Velasco, Jesus, Whaley, Kevin J., Altmann, Friedrich, Gruber, Clemens, Steinkellner, Herta, Honko, Anna N., Kuehne, Ana I., Aman, M. Javad, Sahandi, Sara, Enterlein, Sven, Zhan, Xiaoguo, Enria, Delia, Geisbert, Thomas W.

“…Countermeasures against potential biothreat agents remain important to US Homeland Security, and many of these pharmaceuticals could have dual use in the…”
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Withaferin A is a potent inhibitor of angiogenesis by MOHAN, Royce, HAMMERS, Hans J, PRIBLUDA, Victor S, BARGAGNA-MOHAN, Paola, ZHAN, Xiaoguo H, HERBSTRITT, Christopher J, RUIZ, Antonio, LI ZHANG, HANSON, Art D, CONNER, Barry P, ROUGAS, John

“…The medicinal plant Withania somnifera is widely researched for its anti-inflammatory, cardioactive and central nervous system effects. In Ayurveda , the major…”
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Murine missing in metastasis (MIM) mediates cell polarity and regulates the motility response to growth factors by Yu, Dan, Zhan, Xiaoguo H, Niu, Shuqiong, Mikhailenko, Irina, Strickland, Dudley K, Zhu, Jianwei, Cao, Meng, Zhan, Xi

“…Missing in metastasis (MIM) is a member of the inverse BAR-domain protein family, and in vitro studies have implied MIM plays a role in deforming membrane…”
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2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors α and β by LAVALLEE, Theresa M, ZHAN, Xiaoguo H, HERBSTRITT, Chris J, KOUGH, Emily C, GREEN, Shawn J, PRIBLUDA, Victor S

“…2-Methoxyestradiol (2ME(2)) is an endogenous metabolite of 17beta-estradiol (E(2)) that arises from the hydroxylation and subsequent methylation at the…”
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Abba promotes PDGF-mediated membrane ruffling through activation of the small GTPase Rac1 by Zheng, Datong, Niu, Shuqiong, Yu, Dan, Zhan, Xiaoguo H., Zeng, Xianchun, Cui, Bota, Chen, Yanping, Yoon, Jennifer, Martin, Stuart S., Lu, Xiang, Zhan, Xi

“…► Overexpression of Abba increases the dorsal ruffling mediated by PDGF. ► Abba activates Rac1 upon PDGF stimuli. ► PDGF treatment increases the association of…”
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2-Methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway by LAVALLEE, Theresa M, ZHAN, Xiaoguo H, JOHNSON, Michelle S, HERBSTRITT, Chris J, SWARTZ, Glenn, WILLIAMS, Mark S, HEMBROUGH, Wendy A, GREEN, Shawn J, PRIBLUDA, Victor S

“…2-Methoxyestradiol (2ME2), a natural metabolite of estradiol, is a potent antitumor and antiangiogenic agent. In vitro, 2ME2 inhibits the proliferation of a…”
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Synthesis, antiproliferative, and pharmacokinetic properties of 3- and 17-double-modified analogs of 2-methoxyestradiol by Agoston, Gregory E., Shah, Jamshed H., Suwandi, Lita, Hanson, Arthur D., Zhan, Xiaoguo, LaVallee, Theresa M., Pribluda, Victor, Treston, Anthony M.

“…A series of doubly modified analogs of 2-methoxyestradiol were designed, synthesized and evaluated for antiproliferative, antiangiogenic, estrogenic and…”
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Synthesis and antitumor activities of 3-modified 2-methoxyestradiol analogs by Suwandi, Lita S., Agoston, Gregory E., Shah, Jamshed H., Hanson, Arthur D., Zhan, Xiaoguo H., LaVallee, Theresa M., Treston, Anthony M.

“…A lead-generation series of analogs of 2-methoxyestradiol modified at the 3-position were designed, synthesized and evaluated for antiproliferative,…”
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Synthesis of 2- and 17-substituted estrone analogs and their antiproliferative structure–activity relationships compared to 2-methoxyestradiol by Shah, Jamshed H., Agoston, Gregory E., Suwandi, Lita, Hunsucker, Kimberly, Pribluda, Victor, Zhan, Xiaoguo H., Swartz, Glenn M., LaVallee, Theresa M., Treston, Anthony M.

“…A novel series of 17-modified and 2,17-modified analogs of 2-methoxyestradiol (2ME2) were synthesized and characterized. These analogs were designed to retain…”
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Synthesis and structure–activity relationships of 16-modified analogs of 2-methoxyestradiol by Agoston, Gregory E., Shah, Jamshed H., LaVallee, Theresa M., Zhan, Xiaoguo, Pribluda, Victor S., Treston, Anthony M.

“…A series of 16-substituted 2-methoxyestradiol analogs were synthesized and evaluated for antiproliferative activity, estrogenicity, and the ability to form…”
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Mice deficient in MIM expression are predisposed to lymphomagenesis by Yu, D, Zhan, X H, Zhao, X F, Williams, M S, Carey, G B, Smith, E, Scott, D, Zhu, J, Guo, Y, Cherukuri, S, Civin, C I, Zhan, X

“…Missing in metastasis (MIM) is a member of newly emerged inverse Bin-Amphiphysin-Rvs (BAR) domain protein family and a putative metastasis suppressor. Although…”
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