Search Results - "Zhalnina, Mariya"

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1 by Bandekar, Sumit J., Chen, Chun-Liang, Ravala, Sandeep K., Cash, Jennifer N., Avramova, Larisa V., Zhalnina, Mariya V., Gutkind, J. Silvio, Li, Sheng, Tesmer, John J.G.

“…Trio is a large and highly conserved metazoan signaling scaffold that contains two Dbl family guanine nucleotide exchange factor (GEF) modules, TrioN and…”
Get full text

Crystal structures of the OmpF porin: function in a colicin translocon by Yamashita, Eiki, Zhalnina, Mariya V, Zakharov, Stanislav D, Sharma, Onkar, Cramer, William A

“…The OmpF porin in the Escherichia coli outer membrane (OM) is required for the cytotoxic action of group A colicins, which are proposed to insert their…”
Get full text

Genome‐wide screens: novel mechanisms in colicin import and cytotoxicity by Sharma, Onkar, Datsenko, Kirill A., Ess, Sara C., Zhalnina, Mariya V., Wanner, Barry L., Cramer, William A.

“…Summary Only two new genes (fkpA and lepB) have been identified to be required for colicin cytotoxicity in the last 25 years. Genome‐wide screening using the…”
Get full text

Pathways of colicin import: utilization of BtuB, OmpF porin and the TolC drug-export protein by Zakharov, Stanislav D, Sharma, Onkar, Zhalnina, Mariya, Yamashita, Eiki, Cramer, William A

“…Pathway I. Group A nuclease colicins parasitize and bind tightly (Kd ≤ 10(-9) M) to the vitamin B12 receptor on which they diffuse laterally in the OM (outer…”
Get more information

Structure of the complex of the colicin E2 R-domain and its BtuB receptor. The outer membrane colicin translocon by Sharma, Onkar, Yamashita, Eiki, Zhalnina, Mariya V, Zakharov, Stanislav D, Datsenko, Kirill A, Wanner, Barry L, Cramer, William A

“…The crystal structure of the complex of the BtuB receptor and the 135-residue coiled-coil receptor-binding R-domain of colicin E3 (E3R135) suggested a novel…”
Get full text

Primary Events in the Colicin Translocon: FRET Analysis of Colicin Unfolding Initiated by Binding to BtuB and OmpF by Zakharov, Stanislav D, Sharma, Onkar, Zhalnina, Mariya V, Cramer, William A

“…Cellular import of colicin E3 is initiated by high affinity binding of the colicin receptor-binding (R) domain to the vitamin B12 (BtuB) receptor in the…”
Get full text

The structure of BtuB with bound colicin E3 R-domain implies a translocon by Cramer, William A, Kurisu, Genji, Zakharov, Stanislav D, Zhalnina, Mariya V, Bano, Sufiya, Eroukova, Veronika Y, Rokitskaya, Tatiana I, Antonenko, Yuri N, Wiener, Michael C

“…Cellular import of colicin E3 is initiated by the Escherichia coli outer membrane cobalamin transporter, BtuB. The 135-residue 100-A coiled-coil…”
Get full text

Colicin Occlusion of OmpF and TolC Channels: Outer Membrane Translocons for Colicin Import by Zakharov, Stanislav D., Eroukova, Veronika Y., Rokitskaya, Tatyana I., Zhalnina, Mariya V., Sharma, Onkar, Loll, Patrick J., Zgurskaya, Helen I., Antonenko, Yuri N., Cramer, William A.

“…The interaction of colicins with target cells is a paradigm for protein import. To enter cells, bactericidal colicins parasitize Escherichia coli outer…”
Get full text

The Colicin E3 Outer Membrane Translocon:  Immunity Protein Release Allows Interaction of the Cytotoxic Domain with OmpF Porin by Zakharov, Stanislav D, Zhalnina, Mariya V, Sharma, Onkar, Cramer, William A

“…The crystal structure previously obtained for the complex of BtuB and the receptor binding domain of colicin E3 forms a basis for further analysis of the…”
Get full text

Methods for studying interactions of detergents and lipids with α-helical and β-barrel integral membrane proteins by Hasan, S Saif, Baniulis, Danas, Yamashita, Eiki, Zhalnina, Mariya V, Zakharov, Stanislav D, Stofleth, Jason T, Cramer, William A

“…Methods for studying interactions of protein with lipids and detergents are described for representatives of two major classes of membrane proteins: (1) the…”
Get more information

Structure of the Complex of the Colicin E2 R-domain and Its BtuB Receptor by Sharma, Onkar, Yamashita, Eiki, Zhalnina, Mariya V., Zakharov, Stanislav D., Datsenko, Kirill A., Wanner, Barry L., Cramer, William A.

“…The crystal structure of the complex of the BtuB receptor and the 135-residue coiled-coil receptor-binding R-domain of colicin E3 (E3R135) suggested a novel…”
Get full text

Insertion of Colicin E1 into Omp TolC is Mediated by the Ordered Segment of Translocation Domain by Zakharov, Stanislav D., Zhalnina, Mariya V., Cramer, William A.

Get full text

Membrane Protein Crystallization in Lipidic Mesophases with Tailored Bilayers by Misquitta, Lisa V., Misquitta, Yohann, Cherezov, Vadim, Slattery, Orla, Mohan, Jakkam M., Hart, David, Zhalnina, Mariya, Cramer, William A., Caffrey, Martin

“…Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms…”
Get full text

Protein Translocation Across Membranes: Components of Outer Membrane Colicin Translocons by Zakharov, Stanislav D., Sharma, Onkar, Yamashita, Eiki, Zhalnina, Mariya V., Datsenko, Kirill A., Ess, Sara, Wanner, Barry L., Cramer, William A.

Get full text

Molecular mechanism of protein import through receptor complexes: implication of the complex structure of outer membrane receptor and colicin E3 by Genji, Kurisu, Zakharov, Stanilav D, Zhalnina, Mariya V, Cramer, William A

Get more information