Search Results - "Zhai, Yiwen"
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Analysis of differentially expressed genes discovers Latroeggtoxin VI-induced changes and SYNJ1 as a main target in PC12 cells
Published in BMC genomics (04-09-2023)“…Abstract Background Previous preliminary work found that Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin from the eggs of spider Latrodectus…”
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Latroeggtoxin-VI protects nerve cells and prevents depression by inhibiting NF-κB signaling pathway activation and excessive inflammation
Published in Frontiers in immunology (15-05-2023)“…Depression has a high incidence and seriously endangers human health. Accumulated evidence indicates that targeting neuroinflammation is a potential avenue for…”
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Punicalagin Mollifies Lead Acetate-Induced Oxidative Imbalance in Male Reproductive System
Published in International journal of molecular sciences (11-08-2016)“…Punicalagin (PU) is a known antioxidant. The present study examined PU to protect against lead-induced oxidative stress (OS) testicular damage in mice…”
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Insights into the mediation of Ca2+ signaling in the promoting effects of LETX-VI on the synthesis and release of dopamine
Published in Journal of cell communication and signaling (01-12-2023)“…Latroeggtoxin-VI (LETX-VI) is an active protein and was previously demonstrated to have effects on the synthesis and release of dopamine. Hererin, the…”
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Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson's disease
Published in Biological research (16-03-2024)“…Parkinson's disease (PD) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive α-synuclein facilitating Lewy body…”
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CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression
Published in Scientific reports (15-10-2020)“…CHARGE syndrome, a rare multiple congenital anomaly condition, is caused by haploinsufficiency of the chromatin remodeling protein gene CHD7 (Chromodomain…”
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Excessive nerve growth factor impairs bidirectional communication between the oocyte and cumulus cells resulting in reduced oocyte competence
Published in Reproductive biology and endocrinology (27-03-2018)“…Excessive nerve growth factor (NGF) is commonly found in the follicular fluid of patients with polycystic ovary syndrome (PCOS). Furthermore, oocytes from PCOS…”
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Pull-Down Assay-Guided Insights into the Effects of Latroeggtoxin-VI on Nerve Cells
Published in Toxins (12-02-2021)“…Latroeggtoxin-VI (LETX-VI) is a peptide neurotoxin newly found from the eggs of spider To explore the mechanism of action of the LETX-VI on nerve cells, the…”
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BBX7 interacts with BBX8 to accelerate flowering in chrysanthemum
Published in Molecular horticulture (01-04-2023)“…Abstract The quantitative control of FLOWERING LOCUS T (FT) activation is important for the floral transition in flowering plants. However, the flowering…”
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Identification of pathogenic mutation in a Chinese pedigree affected with split hand/split foot malformation
Published in Zhonghua yi xue yi chuan xue za zhi (10-12-2018)“…To detect potential mutation in a Chinese pedigree affected with split hand/split foot malformation (SHFM). The patients were screened for genome-wide copy…”
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Incorporation of exome‐based CNV analysis makes trio‐WES a more powerful tool for clinical diagnosis in neurodevelopmental disorders: A retrospective study
Published in Human mutation (01-08-2021)“…Neurodevelopmental disorders (NDDs) are a genetically heterogeneous group of diseases, affecting 1%–3% of children. Whole‐exome sequencing (WES) has been…”
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Self-powered fluorescence display devices based on a fast self-charging/recharging battery (Mg/Prussian blue)
Published in Chemical science (Cambridge) (01-01-2016)“…Stimuli-responsive (such as voltage and/or light) fluorescence display systems have attracted particular attention in their promising fields of application…”
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An ethylene‐responsive transcription factor and a B‐box protein coordinate vegetative growth and photoperiodic flowering in chrysanthemum
Published in Plant, cell and environment (01-02-2023)“…Plants employ several endogenous and exogenous signals to guarantee timely floral transitions with floral integrators. To avoid premature flowering, flowering…”
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Rab3 and synaptotagmin proteins in the regulation of vesicle fusion and neurotransmitter release
Published in Life sciences (1973) (15-11-2022)Get full text
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Effects of latroeggtoxin-VI on dopamine and [alpha]-synuclein in PC12 cells and the implications for Parkinson's disease
Published in Biological research (16-03-2024)“…Parkinson's disease (PD) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive [alpha]-synuclein facilitating Lewy body…”
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PC12 Cell Conditional Medium Prepared after Latroeggtoxin-VI Treatment Suppresses Glioma Cells
Published in International journal of peptide research and therapeutics (16-07-2024)“…Latroeggtoxin-VI (LETX-VI) is a proteinaceous toxin found in the eggs of spider Latrodectus tredecimguttatus and was previously shown to promote the synthesis…”
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17
Insights into the mediation of Ca 2+ signaling in the promoting effects of LETX-VI on the synthesis and release of dopamine
Published in Journal of cell communication and signaling (01-12-2023)“…Latroeggtoxin-VI (LETX-VI) is an active protein and was previously demonstrated to have effects on the synthesis and release of dopamine. Hererin, the…”
Get full text
Journal Article -
18
Synaptotagmin 1-mediated cell membrane penetration and dopamine release enhancement by latroeggtoxin-VI
Published in International journal of biological macromolecules (01-09-2022)“…Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin mined from the egg transcriptome of spider L. tredecimguttatus, was previously found to promote the…”
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Biochemical and cytotoxic evaluation of latroeggtoxin‐VI against PC12 cells
Published in Journal of biochemical and molecular toxicology (01-08-2021)“…Latroeggtoxin‐VI (LETX‐VI) is a peptide neurotoxin discovered from Latrodectus tredecimguttatus eggs. In the current study, the action features of the…”
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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
Published in Cell (22-08-2024)“…Immune tolerance mechanisms are shared in cancer and pregnancy. Through cross-analyzing single-cell RNA-sequencing data from multiple human cancer types and…”
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