Search Results - "Zhai, Kan"

Single-cell analysis of diverse immune phenotypes in malignant pleural effusion by Huang, Zhong-Yin, Shao, Ming-Ming, Zhang, Jian-Chu, Yi, Feng-Shuang, Du, Juan, Zhou, Qiong, Wu, Feng-Yao, Li, Sha, Li, Wei, Huang, Xian-Zhen, Zhai, Kan, Shi, Huan-Zhong

“…The complex interactions among different immune cells have important functions in the development of malignant pleural effusion (MPE). Here we perform…”
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Detection of Human Papillomavirus DNA in Patients with Breast Tumor in China by Li, Jie, Ding, Jie, Zhai, Kan

“…The presence of HPV in breast tissue and the potential causal association between human papillomavirus (HPV) and breast cancer (BC) remains controversial. The…”
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Dynamics of host immune responses and a potential function of Trem2hi interstitial macrophages in Pneumocystis pneumonia by Yang, Hu-Qin, Sun, Han, Li, Kang, Shao, Ming-Ming, Zhai, Kan, Tong, Zhao-Hui

“…Abstract Background Pneumocystis pneumonia (PCP) is a life-threatening opportunistic fungal infection with a high mortality rate in immunocompromised patients,…”
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Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations by Lin, Dongxin, Wu, Chen, Hu, Zhibin, He, Zhonghu, Jia, Weihua, Wang, Feng, Zhou, Yifeng, Liu, Zhihua, Zhan, Qimin, Liu, Yu, Yu, Dianke, Zhai, Kan, Chang, Jiang, Qiao, Yan, Jin, Guangfu, Liu, Zhe, Shen, Yuanyuan, Guo, Chuanhai, Fu, Jianhua, Miao, Xiaoping, Tan, Wen, Shen, Hongbing, Ke, Yang, Zeng, Yixin, Wu, Tangchun

“…Esophageal squamous-cell carcinoma (ESCC) is one of the most prevalent cancers worldwide and occurs at a relatively high frequency in China. To identify…”
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Macrophage-derived exosome promotes regulatory T cell differentiation in malignant pleural effusion by Shao, Ming-Ming, Pei, Xue-Bin, Chen, Qing-Yu, Wang, Feng, Wang, Zhen, Zhai, Kan

“…Tumor-associated macrophages are one of the key components of the tumor microenvironment. The immunomodulatory activity and function of macrophages in…”
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Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions by Wu, Chen, Kraft, Peter, Zhai, Kan, Chang, Jiang, Wang, Zhaoming, Li, Yun, Hu, Zhibin, He, Zhonghu, Jia, Weihua, Abnet, Christian C, Liang, Liming, Hu, Nan, Miao, Xiaoping, Zhou, Yifeng, Liu, Zhihua, Zhan, Qimin, Liu, Yu, Qiao, Yan, Zhou, Yuling, Jin, Guangfu, Guo, Chuanhai, Lu, Changdong, Yang, Haijun, Fu, Jianhua, Yu, Dianke, Freedman, Neal D, Ding, Ti, Tan, Wen, Goldstein, Alisa M, Wu, Tangchun, Shen, Hongbing, Ke, Yang, Zeng, Yixin, Chanock, Stephen J, Taylor, Philip R, Lin, Dongxin

“…Dongxin Lin and colleagues report a genome-wide association study for esophageal squamous cell carcinoma (ESCC) in Chinese populations, identifying nine new…”
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Hepatocyte growth factor combined with adenosine deaminase as biomarker for diagnosis of tuberculous pleural effusion by Zheng, Sheng-Cai, Huang, Zhong-Yin, Zhai, Kan, Shi, Huan-Zhong, Shao, Ming-Ming

“…The simple, rapid, and accurate diagnosis of tuberculous pleural effusion (TPE) remains difficult. This study aimed to determine the accuracy of hepatocyte…”
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Clinical Value of Tumor Markers for Determining Cause of Pleural Effusion by Gu, Yan, Zhai, Kan, Shi, Huan-Zhong

“…Background： It is often challenging to distinguish tuberculous pleural effusion （TPE） from malignant pleural effusion （MPE）;thoracoscopy is among the…”
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Signatures of B Cell Receptor Repertoire Following Pneumocystis Infection by Sun, Han, Yang, Hu-Qin, Zhai, Kan, Tong, Zhao-Hui

“…B cells play vital roles in host defense against Pneumocystis infection. However, the features of the B cell receptor (BCR) repertoire in disease progression…”
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Prognostic biomarkers of malignant patients with pleural effusion: a systematic review and meta-analysis by Peng, Peng, Yang, Yuan, Du, Juan, Zhai, Kan, Shi, Huan-Zhong

“…Pleural effusion is a common clinical problem in patients with cancer. We aimed to summarize all the known prognostic indicators of malignant pleural effusion…”
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Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations by Chang, Jiang, Tian, Jianbo, Zhu, Ying, Zhong, Rong, Zhai, Kan, Li, Jiaoyuan, Ke, Juntao, Han, QiangQiang, Lou, Jiao, Chen, Wei, Zhu, Beibei, Shen, Na, Zhang, Yi, Gong, Yajie, Yang, Yang, Zou, Danyi, Peng, Xiating, Zhang, Zhi, Zhang, Xuemei, Huang, Kun, Yang, Ming, Wang, Li, Wu, Chen, Lin, Dongxin, Miao, Xiaoping

“…Germline coding variants have not been systematically investigated for pancreatic ductal adenocarcinoma (PDAC). Here we report an exome-wide investigation…”
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Single-Cell TCR Sequencing Reveals the Dynamics of T Cell Repertoire Profiling During Pneumocystis Infection by Yang, Hu-Qin, Wang, Yi-Shan, Zhai, Kan, Tong, Zhao-Hui

“…T cell responses play critical roles in host adaptive immunity against . However, the dynamics and diversity of the T cell immune repertoire in human…”
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Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection by Ma, Dan, Zhang, Qian-Yu, Rong, Heng-Mo, Zhai, Kan, Tong, Zhao-Hui

“…Pneumocystis is a life-threatening fungal pathogen that frequently causes fatal pneumonia (PCP) in immunocompromised individuals. Recently, B cells have been…”
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Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations by Wu, Chen, Miao, Xiaoping, Huang, Liming, Che, Xu, Jiang, Guoliang, Yu, Dianke, Yang, Xianghong, Cao, Guangwen, Hu, Zhibin, Zhou, Yongjian, Zuo, Chaohui, Wang, Chunyou, Zhang, Xianghong, Zhou, Yifeng, Yu, Xianjun, Dai, Wanjin, Li, Zhaoshen, Shen, Hongbing, Liu, Luming, Chen, Yanling, Zhang, Sheng, Wang, Xiaoqi, Zhai, Kan, Chang, Jiang, Liu, Yu, Sun, Menghong, Cao, Wei, Gao, Jun, Ma, Ying, Zheng, Xiongwei, Cheung, Siu Tim, Jia, Yongfeng, Xu, Jian, Tan, Wen, Zhao, Ping, Wu, Tangchun, Wang, Chengfeng, Lin, Dongxin

“…Dongxin Lin and colleagues report a genome-wide association study for pancreatic cancer in Chinese populations. The authors identify five new genetic loci…”
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T Cell Receptor Repertoire Analysis Reveals Signatures of T Cell Responses to Human Mycobacterium tuberculosis by Shao, Ming-Ming, Yi, Feng-Shuang, Huang, Zhong-Yin, Peng, Peng, Wu, Feng-Yao, Shi, Huan-Zhong, Zhai, Kan

“…Characterization of T cell receptor (TCR) repertoires is essential for understanding the mechanisms of infection involving T cell adaptive immunity. The…”
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Genetic Variation in an miRNA-1827 Binding Site in MYCL1 Alters Susceptibility to Small-Cell Lung Cancer by Xiong, Fang, Wu, Chen, Chang, Jiang, Yu, Dianke, Xu, Binghe, Yuan, Peng, Zhai, Kan, Xu, Jian, Tan, Wen, Lin, Dongxin

“…Genetic variations in microRNAs (miRNA) that affect control of their target genes may alter individual susceptibilities to cancer. In this study, we took an in…”
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Diagnostic values of soluble mesothelin-related peptides for malignant pleural mesothelioma: updated meta-analysis by Cui, Ai, Jin, Xiao-Guang, Zhai, Kan, Tong, Zhao-Hui, Shi, Huan-Zhong

“…Objective Although the values of soluble mesothelin-related peptides (SMRPs), including mesothelin and megakaryocyte potentiating factor, in serum and/or…”
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Prognostic impact of pleural effusion in patients with malignancy: A systematic review and meta‐analysis by Yang, Yuan, Du, Juan, Wang, Yi‐Shan, Kang, Han‐YuJie, Zhai, Kan, Shi, Huan‐Zhong

“…The exact role of pleural effusion in the prognosis of cancer patients remains unclear. We aimed to systematically review the prognostic value of pleural…”
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IL-9 Deficiency Promotes Pulmonary Th17 Response in Murine Model of Pneumocystis Infection by Li, Ting, Rong, Heng-Mo, Zhang, Chao, Zhai, Kan, Tong, Zhao-Hui

“…pneumonia (PCP) remains a severe complication with high mortality in immunocompromised patients. It has been well accepted that CD4 T cells play a major role…”
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Influence of age on the diagnostic accuracy of soluble biomarkers for tuberculous pleural effusion: a post hoc analysis by Jiang, Chun-Guo, Wang, Wen, Zhou, Qiong, Wu, Xiu-Zhi, Wang, Xiao-Juan, Wang, Zhen, Zhai, Kan, Shi, Huan-Zhong

“…Accurately diagnosing pleural effusion is a frequent and significant problem in clinical practice. Combining pleural biomarkers with patients' age may be a…”
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