Search Results - "Zhai, ChangLin"
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The Link Between Ferroptosis and Cardiovascular Diseases: A Novel Target for Treatment
Published in Frontiers in cardiovascular medicine (22-07-2021)“…Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and lipid peroxidation. Ferroptosis is distinct from apoptosis,…”
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Ferroptosis: A Novel Therapeutic Target for Ischemia-Reperfusion Injury
Published in Frontiers in cell and developmental biology (10-08-2021)“…Ischemia-reperfusion (I/R) injury is a major cause of cell death and organ damage in numerous pathologies, including myocardial infarction, stroke, and acute…”
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Uncommon culprit artery leading to atypical de winter electrocardiographic changes: a case report
Published in BMC cardiovascular disorders (27-09-2024)“…A subset of patients with acute coronary artery occlusion requiring emergency revascularization, does not present with the typical ECG features of ST-segment…”
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Colchicine Prevents Cardiac Rupture in Mice with Myocardial Infarction by Inhibiting P53-Dependent Apoptosis
Published in International Heart Journal (30-09-2024)“…Cardiac rupture is a fatal complication following myocardial infarction (MI) and there are currently no effective pharmacological strategies for preventing…”
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Role of Trimethylamine N-Oxide in Heart Failure
Published in Reviews in cardiovascular medicine (01-07-2024)“…Heart failure (HF) is a clinical syndrome characterizing by typical physical signs and symptomatology resulting from reduced cardiac output and/or intracardiac…”
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Impact of anemia on in-stent restenosis after percutaneous coronary intervention
Published in BMC cardiovascular disorders (19-11-2021)“…Anemia is a common risk factor for post-percutaneous coronary intervention (PCI) adverse events; however, data on its association with in-stent restenosis…”
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Effect of Radial Artery Compression with a Novel Automatic Pressure-Controlled Radial Compression Device: A Short-Term Prospective Interventional Pilot Study
Published in Journal of interventional cardiology (07-03-2023)“…This study was conducted to design a novel radial compression device with the function of automatic pressure control and evaluate the feasibility and safety of…”
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Targeting Trimethylamine N-Oxide: A New Therapeutic Strategy for Alleviating Atherosclerosis
Published in Frontiers in cardiovascular medicine (13-06-2022)“…Atherosclerosis (AS) is one of the most common cardiovascular diseases (CVDs), and there is currently no effective drug to reverse its pathogenesis…”
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Identification of potential serum biomarkers for congenital heart disease children with pulmonary arterial hypertension by metabonomics
Published in BMC cardiovascular disorders (29-03-2023)“…Pulmonary arterial hypertension is a common complication in patients with congenital heart disease. In the absence of early diagnosis and treatment, pediatric…”
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Coronary functional assessment in non-obstructive coronary artery disease: Present situation and future direction
Published in Frontiers in cardiovascular medicine (23-08-2022)“…Non-obstructive coronary artery disease (CAD), which is defined as coronary stenosis <50%, has been increasingly recognized as an emerging entity in clinical…”
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MicroRNA-206 Protects against Myocardial Ischaemia-Reperfusion Injury in Rats by Targeting Gadd45β
Published in Molecules and cells (31-12-2017)“…MicroRNAs are widely involved in the pathogenesis of cardiovascular diseases through regulating gene expression via translational inhibition or degradation of…”
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MicroRNA-206 Protects against Myocardial Ischaemia-Reperfusion Injury in Rats by Targeting Gadd45β
Published in Molecules and cells (2017)“…MicroRNAs are widely involved in the pathogenesis of cardiovascular diseases through regulating gene expression via translational inhibition or degradation of…”
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Cardioprotective Strategies After Ischemia–Reperfusion Injury
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01-01-2024)“…Acute myocardial infarction (AMI) is associated with high morbidity and mortality worldwide. Although early reperfusion is the most effective strategy to…”
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Ferroptosis: A potential therapeutic target in autoimmune disease (Review)
Published in Experimental and therapeutic medicine (01-08-2023)“…Ferroptosis is a distinct type of regulated cell death characterized by iron overload and lipid peroxidation. Ferroptosis is regulated by numerous factors and…”
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LncRNA AK087124/miR-224-5p/PTEN axis modulates endothelial cell injury in atherosclerosis through apoptosis and AKT signaling pathway
Published in Archives of biochemistry and biophysics (15-07-2021)“…Noncoding RNAs (ncRNAs) have been shown to play important roles in atherosclerosis-related endothelial cells dysfunction during atherosclerosis processes. In…”
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Knockdown of circ_0060745 alleviates acute myocardial infarction by suppressing NF‐κB activation
Published in Journal of cellular and molecular medicine (01-11-2020)“…It has been shown that circRNAs are involved in the development of heart diseases. However, few studies explored the role of circRNAs in acute myocardial…”
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Intestinal Flora Metabolite Trimethylamine Oxide Is Inextricably Linked to Coronary Heart Disease
Published in Journal of cardiovascular pharmacology (01-03-2023)“…Atherosclerotic coronary heart disease is a common cardiovascular disease with high morbidity and mortality. In recent years, the incidence of coronary heart…”
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A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes
Published in FEBS letters (25-08-2014)“…•HIF-1α and miR-21 are induced under hypoxia.•HIF-1α increases miR-21 expression via binding to its promoter, in turn, miR-21 upregulates HIF-1α…”
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