Search Results - "Zha, Didi"

Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation by Douillet, Delphine, Sze, Christie C., Ryan, Caila, Piunti, Andrea, Shah, Avani P., Ugarenko, Michal, Marshall, Stacy A., Rendleman, Emily J., Zha, Didi, Helmin, Kathryn A., Zhao, Zibo, Cao, Kaixiang, Morgan, Marc A., Singer, Benjamin D., Bartom, Elizabeth T., Smith, Edwin R., Shilatifard, Ali

“…The COMPASS protein family catalyzes histone H3 Lys 4 (H3K4) methylation and its members are essential for regulating gene expression. MLL2/COMPASS methylates…”
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Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia by Wang, Lu, Birch, Noah Warren, Zhao, Zibo, Nestler, Carson Meredith, Kazmer, Alexander, Shilati, Anthony, Blake, Alisha, Ozark, Patrick Alexander, Rendleman, Emily Jane, Zha, Didi, Ryan, Caila Ann, Morgan, Marc Alard Jonathan, Shilatifard, Ali

“…Mutations of ASXL1, encoding a component of the BAP1 histone H2A deubiquitinase complex, occur in human myeloid neoplasms and are uniformly associated with…”
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Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family by Sze, Christie C, Ozark, Patrick A, Cao, Kaixiang, Ugarenko, Michal, Das, Siddhartha, Wang, Lu, Marshall, Stacy A, Rendleman, Emily J, Ryan, Caila A, Zha, Didi, Douillet, Delphine, Chen, Fei Xavier, Shilatifard, Ali

“…Set1A and Set1B, two members of the COMPASS family of methyltransferases that methylate the histone H3 lysine 4 (H3K4) residue, have been accredited as primary…”
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Proteomic Profiling of Fallopian Tube-Derived Extracellular Vesicles Using a Microfluidic Tissue-on-Chip System by Zha, Didi, Rayamajhi, Sagar, Sipes, Jared, Russo, Angela, Pathak, Harsh B, Li, Kailiang, Sardiu, Mihaela E, Bantis, Leonidas E, Mitra, Amrita, Puri, Rajni V, Trinidad, Camille V, Cain, Brian P, Isenberg, Brett C, Coppeta, Jonathan, MacLaughlan, Shannon, Godwin, Andrew K, Burdette, Joanna E

“…The human fallopian tube epithelium (hFTE) is the site of fertilization, early embryo development, and the origin of most high-grade serous ovarian cancers…”
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Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression by Zheng, Bin, Aoi, Yuki, Shah, Avani P, Iwanaszko, Marta, Das, Siddhartha, Rendleman, Emily J, Zha, Didi, Khan, Nabiha, Smith, Edwin R, Shilatifard, Ali

“…The regulation of gene expression catalyzed by RNA polymerase II (Pol II) requires a host of accessory factors to ensure cell growth, differentiation, and…”
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A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells by Cenik, Bercin K, Sze, Christie C, Ryan, Caila A, Das, Siddhartha, Cao, Kaixiang, Douillet, Delphine, Rendleman, Emily J, Zha, Didi, Khan, Nabiha Haleema, Bartom, Elizabeth, Shilatifard, Ali

“…Embryonic stem cells (ESCs) are defined by their ability to self-renew and the potential to differentiate into all tissues of the developing organism. We…”
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A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform by Campo, Hannes, Zha, Didi, Pattarawat, Pawat, Colina, Jose, Zhang, Delong, Murphy, Alina, Yoon, Julia, Russo, Angela, Rogers, Hunter B, Lee, Hoi Chang, Zhang, Jiyang, Trotter, Katy, Wagner, Sarah, Ingram, Asia, Pavone, Mary Ellen, Dunne, Sara Fernandez, Boots, Christina E, Urbanek, Margrit, Xiao, Shuo, Burdette, Joanna E, Woodruff, Teresa K, Kim, J Julie

“…To accurately phenocopy human biology , researchers have been reducing their dependence on standard, static two-dimensional (2D) cultures and instead are…”
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Abstract B041: Modeling the malignant transformation of fallopian tube epithelium driven by extracellular vesicles cargos in an organ-on-chip microphysiological system by Zha, Didi, Sipes, Jared, Rayamajhi, Sagar, Bantis, Leonidas E., Russo, Angela, Pathak, Harsh, Godwin, Andrew K., Burdette, Joanna E.

“…Abstract Epithelial ovarian cancer (EOC) remains the leading cause of death from gynecological malignancy and the fifth leading cause of all cancer-related…”
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