Search Results - "Zeyu, Xiong"

Red blood cell microparticles show altered inflammatory chemokine binding and release ligand upon interaction with platelets by Xiong, Zeyu, Cavaretta, John, Qu, Lirong, Stolz, Donna Beer, Triulzi, Darrell, Lee, Janet S.

“…BACKGROUND: Storage of red blood cells (RBCs) under standard blood bank conditions results in reduced structural integrity leading to membrane budding and…”
Get full text

An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity by YU YANG, FAN YANG, ZEYU XIONG, YAN YAN, XINMEN WANG, NISHINO, Michiya, MIRKOVIC, Dragan, NGUYEN, Justin, HONG WANG, YANG, Xiao-Feng

“…Bcl-xL plays a critical role in maintaining cell survival. However, the relationship between the potential interaction of Bcl-xL with other cytosolic proteins…”
Get full text

Thrombospondin-1 Restricts Interleukin-36γ-Mediated Neutrophilic Inflammation during Pseudomonas aeruginosa Pulmonary Infection by Peñaloza, Hernán F, Olonisakin, Tolani F, Bain, William G, Qu, Yanyan, van der Geest, Rick, Zupetic, Jill, Hulver, Mei, Xiong, Zeyu, Newstead, Michael W, Zou, Chunbin, Alder, Jonathan K, Ybe, Joel A, Standiford, Theodore J, Lee, Janet S

“…Interleukin-36γ (IL-36γ), a member of the IL-1 cytokine superfamily, amplifies lung inflammation and impairs host defense during acute pulmonary infection. To…”
Get full text

Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity by Balasubramanian, Krishnakumar, Maeda, Akihiro, Lee, Janet S, Mohammadyani, Dariush, Dar, Haider Hussain, Jiang, Jian Fei, St Croix, Claudette M, Watkins, Simon, Tyurin, Vladimir A, Tyurina, Yulia Y, Klöditz, Katharina, Polimova, Anastassia, Kapralova, Valentyna I, Xiong, Zeyu, Ray, Prabir, Klein-Seetharaman, Judith, Mallampalli, Rama K, Bayir, Hülya, Fadeel, Bengt, Kagan, Valerian E

“…Among the distinct molecular signatures present in the mitochondrion is the tetra-acylated anionic phospholipid cardiolipin, a lipid also present in…”
Get more information

Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation by Mangalmurti, Nilam S., Xiong, Zeyu, Hulver, Mei, Ranganathan, Mrunalini, Liu, Xiang Hong, Oriss, Timothy, Fitzpatrick, Meghan, Rubin, Marc, Triulzi, Darrell, Choi, Augustine, Lee, Janet S.

“…Red cell transfusions are associated with the development of acute lung injury in the critically ill. Recent evidence suggests that storage induced alterations…”
Get full text

Induction of Fetal Hemoglobin by Introducing Natural Hereditary Persistence of Fetal Hemoglobin Mutations in the γ-Globin Gene Promoters for Genome Editing Therapies for β-Thalassemia by Lu, Dian, Xu, Zhiliang, Peng, Zhiyong, Yang, Yinghong, Song, Bing, Xiong, Zeyu, Ma, Zhirui, Guan, Hongmei, Chen, Bangzhu, Nakamura, Yukio, Zeng, Juan, Liu, Nengqing, Sun, Xiaofang, Chen, Diyu

“…Reactivation of γ-globin expression is a promising therapeutic approach for β-hemoglobinopathies. Here, we propose a novel Cas9/AAV6-mediated genome editing…”
Get full text

Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling by Pinilla-Vera, Miguel, Xiong, Zeyu, Zhao, Yutong, Zhao, Jing, Donahoe, Michael P, Barge, Suchitra, Horne, William T, Kolls, Jay K, McVerry, Bryan J, Birukova, Anastasiya, Tighe, Robert M, Foster, W Michael, Hollingsworth, John, Ray, Anuradha, Mallampalli, Rama, Ray, Prabir, Lee, Janet S

“…Despite recent advances in understanding macrophage activation, little is known regarding how human alveolar macrophages in health calibrate its…”
Get full text

The safety and effectiveness of genetically corrected iPSCs derived from β-thalassaemia patients in nonmyeloablative β-thalassaemic mice by Xian, Yexing, Xie, Yingjun, Song, Bing, Ou, Zhanhui, Ouyang, Shuming, Xie, Yuhuan, Yang, Yi, Xiong, Zeyu, Li, Haoxian, Sun, Xiaofang

“…Abstract Background β-Thalassaemia is a clinically common cause of hereditary haemolytic anaemia stemming from mutations in important functional regions of the…”
Get full text

CRISPR/Cas9 gene correction of HbH-CS thalassemia-induced pluripotent stem cells by Yingjun, Xie, Yuhuan, Xie, Yuchang, Chen, Dongzhi, Li, Ding, Wang, Bing, Song, Yi, Yang, Dian, Lu, Yanting, Xue, Zeyu, Xiong, Nengqing, Liu, Diyu, Chen, Xiaofang, Sun

“…Haemoglobin (Hb) H-constant spring (CS) alpha thalassaemia (- -/-α CS ) is the most common type of nondeletional Hb H disease in southern China. The…”
Get full text

Phagocytosis is a primary determinant of pulmonary clearance of clinical Klebsiella pneumoniae isolates by van der Geest, Rick, Fan, Hongye, Peñaloza, Hernán F, Bain, William G, Xiong, Zeyu, Kohli, Naina, Larson, Emily, Sullivan, Mara L G, Franks, Jonathan M, Stolz, Donna B, Ito, Ryota, Chen, Kong, Doi, Yohei, Harriff, Melanie J, Lee, Janet S

“…( ) is a common cause of hospital-acquired pneumonia. Although previous studies have suggested that evasion of phagocytic uptake is a virulence determinant of…”
Get full text

Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b by He, Wenteng, Zhang, Xiaobai, Zhang, Yalin, Zheng, Weisheng, Xiong, Zeyu, Hu, Xinjie, Wang, Mingzhu, Zhang, Linfeng, Zhao, Kun, Qiao, Zhibin, Lai, Weiyi, Lv, Cong, Kou, Xiaochen, Zhao, Yanhong, Yin, Jiqing, Liu, Wenqiang, Jiang, Yonghua, Chen, Mo, Xu, Ruimin, Le, Rongrong, Li, Chong, Wang, Hong, Wan, Xiaoping, Wang, Hailin, Han, Zhiming, Jiang, Cizhong, Gao, Shaorong, Chen, Jiayu

“…Androgenetic haploid embryonic stem cells (AG-haESCs) hold great promise for exploring gene functions and generating gene-edited semi-cloned (SC) mice…”
Get full text

Prophylactic administration of parenteral steroids for preventing airway complications after extubation in adults: meta-analysis of randomised placebo controlled trials by Fan, Tao, Wang, Gang, Mao, Bing, Xiong, Zeyu, Zhang, Yu, Liu, Xuemei, Wang, Lei, Yang, Sai

“…Objective To determine whether steroids are effective in preventing laryngeal oedema after extubation and reducing the need for subsequent reintubation in…”
Get full text

Duffy antigen receptor for chemokines mediates chemokine endocytosis through a macropinocytosis-like process in endothelial cells by Zhao, Yani, Mangalmurti, Nilam S, Xiong, Zeyu, Prakash, Bharat, Guo, Fengli, Stolz, Donna B, Lee, Janet S

“…The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes…”
Get full text

Generation of GZKHQi001-A and GZWWTi001-A, two induced pluripotent stem cell lines derived from peripheral blood mononuclear cells of Duchenne muscular dystrophy patients by Yuhuan, Xie, Yingjun, Xie, Yanting, Xue, Yuchang, Chen, Bing, Song, Shaoying, Li, Haoxian, Li, Yexing, Xian, Shuming, Ouyang, Zeyu, Xiong, Xiaofang, Sun

“…Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in the DMD gene, which spans ~2.4Mb of genomic sequence at locus Xp21. This…”
Get full text

Platelets inhibit apoptotic lung epithelial cell death and protect mice against infection-induced lung injury by Bain, William, Olonisakin, Tolani, Yu, Minting, Qu, Yanyan, Hulver, Mei, Xiong, Zeyu, Li, Huihua, Pilewski, Joseph, Mallampalli, Rama K., Nouraie, Mehdi, Ray, Anuradha, Ray, Prabir, Cheng, Zhenyu, Shanks, Robert M.Q., St. Croix, Claudette, Silverstein, Roy L., Lee, Janet S.

“…Thrombocytopenia is associated with worse outcomes in patients with acute respiratory distress syndrome, which is most commonly caused by infection and marked…”
Get full text

Sickle Cell Trait Increases Red Blood Cell Storage Hemolysis and Post-Transfusion Clearance in Mice by Osei-Hwedieh, David O., Kanias, Tamir, Croix, Claudette St, Jessup, Morgan, Xiong, Zeyu, Sinchar, Derek, Franks, Jonathan, Xu, Qinzi, M. Novelli, Enrico, Sertorio, Jonas T., Potoka, Karin, Binder, Robert J., Basu, Swati, Belanger, Andrea M., Kim-Shapiro, Daniel B., Triulzi, Darrell, Lee, Janet S., Gladwin, Mark T.

“…Transfusion of blood at the limits of approved storage time is associated with lower red blood cell (RBC) post-transfusion recovery and hemolysis, which…”
Get full text

Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes by Ng, Bernard, Yang, Fan, Huston, David P., Yan, Yan, Yang, Yu, Xiong, Zeyu, Peterson, Leif E., Wang, Hong, Yang, Xiao-Feng

“…Alternative splicing is important for increasing the complexity of the human proteome from a limited genome. Previous studies have shown that for some…”
Get full text

An inverse elastic method of crack identification based on sparse strain sensing sheet by Xiong, Zeyu, Glisic, Branko

“…Reliable damage detection over large areas of structures can be achieved by spatially quasi-continuous structural health monitoring enabled by two-dimensional…”
Get full text

Novel tumor antigens elicit anti-tumor humoral immune reactions in a subset of patients with polycythemia vera by Xiong, Zeyu, Yan, Yan, Liu, Enli, Silver, Richard T, Verstovsek, Srdan, Yang, Fan, Wang, Hong, Prchal, Josef, Yang, Xiao-Feng

“…Abstract We attempted to determine whether the immune reactions elicited by aberrantly expressed testis antigens contribute to the beneficial responses to…”
Get full text

Expression of TCTP antisense in CD25high regulatory T cells aggravates cuff-injured vascular inflammation by Xiong, Zeyu, Yan, Yan, Song, Jian, Fang, Pu, Yin, Ying, Yang, Yu, Cowan, Alan, Wang, Hong, Yang, Xiao-Feng

“…Abstract This study examines our hypothesis that translationally controlled tumor protein (TCTP) expression in CD4+ CD25high regulatory T cells (Tregs) is…”
Get full text