Search Results - "Zeslawska, E"

Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents by Waszkielewicz, A.M., Gunia-Krzyżak, A., Powroźnik, B., Słoczyńska, K., Pękala, E., Walczak, M., Bednarski, M., Żesławska, E., Nitek, W., Marona, H.

“…[Display omitted] A series of thirty N-(phenoxy)alkyl or N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols has been designed, synthesized and evaluated for…”
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Influence of Amodiaquine on the Antimalarial Activity of Ellagic Acid: Crystallographic and Biological Studies by Żesławska, Ewa, Oleksyn, Barbara, Fabre, Aude, Benoit-Vical, Françoise

“…In the search for new antimalarial drugs, design of hybrid molecules is recommended to improve biological activity and to decrease the risk of parasite…”
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EFFECT OF CHALCOGEN SUBSTITUENTS (X=Se, S, O) ON MOLECULAR PROPERTIES OF 5-p-CHLOROBENZYLIDENE-3-METHYL-2-X-HYDANTOIN: X-RAY, PM-3 AND DATABASE STUDY by Zesławska, E., Oleksyn, B. J., Korohoda, M. J., Śliwiński, J.

“…The X-ray structure analysis of a single crystal of 5-p-chlorobenzylidene-3-metyl-2-Se-hydantoin was carried out. It revealed that the molecule is a 2 isomer…”
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Design of Novel and Selective Inhibitors of Urokinase-type Plasminogen Activator with Improved Pharmacokinetic Properties for Use as Antimetastatic Agents by Schweinitz, Andrea, Steinmetzer, Torsten, Banke, Ingo J., Arlt, Matthias J.E., Stürzebecher, Anne, Schuster, Oliver, Geissler, Andreas, Giersiefen, Helmut, Zeslawska, Ewa, Jacob, Uwe, Krüger, Achim, Stürzebecher, Jörg

“…The serine protease urokinase-type plasminogen activator (uPA) interacts with a specific receptor (uPAR) on the surface of various cell types, including tumor…”
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Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors by Zeslawska, Ewa, Jacob, Uwe, Schweinitz, Andrea, Coombs, Gary, Bode, Wolfram, Madison, Edwin

“…Urokinase type plasminogen activator (uPA), a trypsin-like serine proteinase, plays an important role in normal tissue re-modelling, cell adhesion, and cell…”
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The Crystal and Molecular Structure of 3-Methyl-5-p-methylbenzylidene-2-selenohydantoin by Żesławska, E., Oleksyn, B. J., Korohoda, M. J., Stadnicka, K.

“…The X-ray structure analysis of a single crystal of 3-methyl-5-p-methylbenzylidene-2-selenohydantoin was carried out. The crystals are monoclinic, space group…”
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The crystal structures of 3-TAPAP in complexes with the urokinase-type plasminogen activator and picrate by Żesławska, Ewa, Jacob, Uwe, Stürzebecher, Jörg, Oleksyn, Barbara J.

“…We have investigated the conformation of a uPA inhibitor in different crystalline environments. The crystal structures of the urokinase-type plasminogen…”
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Amiloride Conformation: The Effect of Different Crystalline Environments by Żesławska, Ewa, Oleksyn, Barbara, Stadnicka, Katarzyna

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Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design by Zeslawska, E, Schweinitz, A, Karcher, A, Sondermann, P, Sperl, S, Stürzebecher, J, Jacob, U

“…Urokinase is a serine protease involved in cancer growth and metastasis. Here we present the first urokinase crystal structure in complex with reversible…”
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