Search Results - "Zerlanko, Brad J."

Premature senescence and increased TGFβ signaling in the absence of Tgif1 by Zerlanko, Brad J, Bartholin, Laurent, Melhuish, Tiffany A, Wotton, David

“…Transforming growth factor β (TGFβ) signaling regulates cell cycle progression in several cell types, primarily by inducing a G1 cell cycle arrest. Tgif1 is a…”
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The αvβ6 Integrin Is Transferred Intercellularly via Exosomes by Fedele, Carmine, Singh, Amrita, Zerlanko, Brad J., Iozzo, Renato V., Languino, Lucia R.

“…Exosomes, cell-derived vesicles of endosomal origin, are continuously released in the extracellular environment and play a key role in intercellular crosstalk…”
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Somatic Mutation of GRIN2A in Malignant Melanoma Results in Loss of Tumor Suppressor Activity via Aberrant NMDAR Complex Formation by Prickett, Todd D., Zerlanko, Brad J., Hill, Victoria K., Gartner, Jared J., Qutob, Nouar, Jiang, Jiji, Simaan, May, Wunderlich, John, Gutkind, J Silvio, Rosenberg, Steven A., Samuels, Yardena

“…The ionotropic glutamate receptors (N-methyl-D-aspartate receptors (NMDARs)) are composed of large complexes of multi-protein subunits creating ion channels in…”
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Integrin αvβ6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2 by DUTTA, Anindita, JING LI, WIXTED, John, VIOLETTE, Shelia M, STEIN, Janet L, STEIN, Gary S, LIAN, Jane B, LANGUINO, Lucia R, HUIMIN LU, AKECH, Jacqueline, PRATAP, Jitesh, TAO WANG, ZERLANKO, Brad J, FITZGERALD, Thomas J, ZHONG JIANG, BIRBE, Ruth

“…The molecular circuitries controlling osseous prostate metastasis are known to depend on the activity of multiple pathways, including integrin signaling. Here,…”
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Inhibition of CtBP1 Activity by Akt-mediated Phosphorylation by Merrill, Jacqueline C., Kagey, Michael H., Melhuish, Tiffany A., Powers, Shannon E., Zerlanko, Brad J., Wotton, David

“…Pc2 (Cbx4) is a member of the chromobox family of polycomb proteins, and is a SUMO E3 ligase for the transcriptional corepressor CtBP1. Here, we show that both…”
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Premature Senescence and Increased TGF[beta] Signaling in the Absence of Tgif1 by Zerlanko, Brad J, Bartholin, Laurent, Melhuish, Tiffany A, Wotton, David

“…Transforming growth factor [beta] (TGF[beta]) signaling regulates cell cycle progression in several cell types, primarily by inducing a G1 cell cycle arrest…”
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The αvβ6 integrin promotes an osteolytic program through upregulation of MMP2 by Dutta, Anindita, Li, Jing, Lu, Huimin, Akech, Jacqueline, Pratap, Jitesh, Wang, Tao, Zerlanko, Brad J., FitzGerald, Thomas J., Jiang, Zhong, Birbe, Ruth, Wixted, John, Violette, Shelia M., Stein, Janet L., Stein, Gary S., Lian, Jane B., Languino, Lucia R.

“…The molecular circuitries controlling osseous prostate metastasis are known to depend on the activity of multiple pathways, including integrin signaling. Here,…”
Get full text