Search Results - "Zenobi, Alessandro"
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NLRC5 promotes transcription of BTN3A1-3 genes and Vγ9Vδ2 T cell-mediated killing
Published in iScience (22-01-2021)“…BTN3A molecules—BTN3A1 in particular—emerged as important mediators of Vγ9Vδ2 T cell activation by phosphoantigens. These metabolites can originate from…”
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Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses
Published in EMBO reports (07-11-2022)“…Anticancer T cells acquire a dysfunctional state characterized by poor effector function and expression of inhibitory receptors, such as PD‐1. Blockade of PD‐1…”
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The bacterial lysate OM-85 engages Toll-like receptors 2 and 4 triggering an immunomodulatory gene signature in human myeloid cells
Published in Mucosal immunology (01-06-2024)“…OM-85 is a bacterial lysate used in clinical practice to reduce duration and frequency of recurrent respiratory tract infections. Whereas knowledge of its…”
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Myc controls NK cell development, IL-15-driven expansion, and translational machinery
Published in Life science alliance (01-07-2023)“…MYC is a pleiotropic transcription factor involved in cancer, cell proliferation, and metabolism. Its regulation and function in NK cells, which are innate…”
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Simple and Quick Method to Obtain a Decellularized, Functional Liver Bioscaffold
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…The development of new approaches for organ transplantation has become crucial in the last years. In particular, organ engineering, involving the preparation…”
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Epigenetic Conversion as a Safe and Simple Method to Obtain Insulin-secreting Cells from Adult Skin Fibroblasts
Published in Journal of visualized experiments (18-03-2016)“…Regenerative medicine requires new, fully functional cells that are delivered to patients in order to repair degenerated or damaged tissues. When such cells…”
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Epigenetic Conversion as a Safe and Simple Method to Obtain Insulin-secreting Cells from Adult Skin Fibroblasts
Published in Journal of visualized experiments (18-03-2016)Get full text
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Erase and Rewind: Epigenetic Conversion of Cell Fate
Published in Stem cell reviews (01-04-2016)“…The potential of cell therapy in regenerative medicine has greatly expanded thanks to the availability of sources of pluripotent cells. In particular, induced…”
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Mountain high and valley deep: epigenetic controls of pluripotency and cell fate
Published in Animal reproduction (2017)Get full text
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