Search Results - "Zenhom, Nagwa M."

Cilostazol alleviates streptozotocin-induced testicular injury in rats via PI3K/Akt pathway by Mohamed, Mervat Z., Hafez, Heba M., Zenhom, Nagwa M., Mohammed, Hanaa Hassanein

“…Male infertility prevalence is higher in diabetic patients. Those patients exhibit testicular oxidative damage due to sustained hyperglycemia and inflammation…”
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Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway by Zenhom, Nagwa M., Rifaai, Rehab A., Morsy, Mohamed A., Al-Taher, Abdulla, Abdel-Gaber, Seham A.

“…Methotrexate (MTX) is a commonly used chemotherapeutic agent. Oxidative stress and inflammation have been proved in the development of MTX toxicity. Paeonol is…”
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Paeonol Attenuates Hepatic Ischemia/Reperfusion Injury by Modulating the Nrf2/HO-1 and TLR4/MYD88/NF-κB Signaling Pathways by Morsy, Mohamed A, Ibrahim, Yasmine F, Abdel Hafez, Sara Mohamed Naguib, Zenhom, Nagwa M, Nair, Anroop B, Venugopala, Katharigatta N, Shinu, Pottathil, Abdel-Gaber, Seham A

“…Hepatic ischemia/reperfusion (HIR) is the most common type of liver injury following several clinical situations. Modulating oxidative stress and inflammation…”
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STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats by Mohamed, Mervat Z., Hafez, Heba M., Mohamed, Hanaa H., Zenhom, Nagwa M.

“…Objective. We aimed to assess the protective role of verapamil, L-type calcium channel blockers, against early lung damage in diabetic rats. Lung injury has…”
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The effect of peptide tyrosine tyrosine (PYY3–36), a selective Y2 receptor agonist on streptozotocin-induced diabetes in albino rats by Abdel-Hamid, Heba A., Abdalla, Mona M. I., Zenhom, Nagwa M., Ahmed, Rasha F.

“…The aim of the present study was to assess the effect of the PYY3–36, as a potential therapy for the type 2 diabetes mellitus (T2DM), induced by high fat diet…”
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Tramadol Induced Adrenal Insufficiency: Histological, Immunohistochemical, Ultrastructural, and Biochemical Genetic Experimental Study by Rifaai, Rehab A., Zenhom, Nagwa M., Ahmed, Rasha F., Hassan, Osama A., Abdelaleem, Shereen Abdelhakim, El-Tahawy, Nashwa F.

“…Tramadol is a synthetic, centrally acting analgesic. It is the most consumed narcotic drug that is prescribed in the world. Tramadol abuse has dramatically…”
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Corrigendum to “Effects of platelet rich plasma on experimentally induced diabetic heart injury” [Int. Immunopharm. 96 (2021) 107814] by Mohamed Naguib Abdel Hafez, Sara, Zenhom, Nagwa M., Abdel-Hamid, Heba A.

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Modified Adenovirus Reduces De Novo Peritoneal Adhesions in Rats and Limits Off-Target Transfection. Role of EZH2 in Adhesion Formation by Atta, Hussein M., Al-Hendy, Ayman A., Abdel Raheim, Salama R., Abdel-Ghany, Hend, Nasif, Khalid A., Abdellah, Ahlam M., Zenhom, Nagwa M., Kamel, Heba S.

“…Aim of the study: Adenovector encoding tissue plasminogen activator (tPA) was shown to reduce experimental peritoneal adhesion. We investigated the targeting…”
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Mechanisms underlying the protective effect of leukotriene receptor antagonist montelukast against doxorubicin induced testicular injury in rats by Mohamed, Mervat Z., Zenhom, Nagwa M.

“…•The cysteinyl leukotriene receptor antagonist montelukast protected against doxorubicin-induced testicular damage.•Montelukast decreased testicular oxidative…”
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Effects of platelet rich plasma on experimentally induced diabetic heart injury by Abdel Hafez, Sara Mohamed Naguib, Zenhom, Nagwa M., Abdel-Hamid, Heba A.

“…•PRP ameliorated the cardiac injury induced by diabetes through inhibition of oxidative stress and inflammation.•It was confirmed by biochemical, histological,…”
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Protective role of nebivolol in cadmium-induced hepatotoxicity via downregulation of oxidative stress, apoptosis and inflammatory pathways by Refaie, Marwa M.M., El-Hussieny, Maram, Zenhom, Nagwa M.

“…•Nebivolol has protective effect in cadmium induced hepatotoxicity.•This is due to its antioxidant effect and anti-inflammatory role.•Vasodilating effect of…”
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Testicular cytoprotective effect of glucagon like peptide-1 in diabetic rats involves inhibition of apoptosis, endoplasmic reticulum stress and activation of autophagy by Abdel-Hakeem, Elshymaa A, Zenhom, Nagwa M, Mokhemer, Sahar A

“…This study aimed to explore the possible cytoprotective effects of exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in the testicles of diabetic…”
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Therapeutic effect of liraglutide on expression of CTGF and BMP‐7 in induced diabetic nephropathy by Ramzy, Maggie M., Abdalla, Ahlam M., Zenhom, Nagwa M., Okasha, Ahmed M., Abdelkafy, Aya E., Saleh, Rabeh K.

“…Introduction Diabetic nephropathy (DN) is one of the critical complications of diabetes mellitus and the main cause of chronic renal dysfunction. The…”
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Role of PPAR‐α agonist fenofibrate in the treatment of induced benign prostatic hyperplasia with dysplastic changes in rats by Refaie, Marwa M.M., Rifaai, Rehab A., Zenhom, Nagwa M.

“…Nearly all men who reach average life expectancy have prostate disease. The most common is benign prostatic hyperplasia (BPH). Peroxisome…”
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Effect of histone deacetylase inhibitor on epithelial‐mesenchymal transition of liver fibrosis by Ramzy, Maggie M., Abdelghany, Hend M, Zenhom, Nagwa M., El‐Tahawy, Nashwa F.

“…Liver fibrosis is an excessively reversible wound healing process and the fibrotic disorder is the activation of hepatic stellate cell that requires extensive…”
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Molecular mechanisms mediate roflumilast protective effect against isoprenaline-induced myocardial injury by Refaie, Marwa Monier Mahmoud, Fouli Gaber Ibrahim, Manar, Fawzy, Michael Atef, Abdel-Hakeem, Elshymaa A., Shaaban Mahmoud Abd El Rahman, Eman, Zenhom, Nagwa M., Shehata, Sayed

“…Background: Myocardial necrosis is one of the most common cardiac and pathological diseases. Unfortunately, using the available medical treatment is not…”
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Effect of experimentally induced hypertension on cerebellum of postmenopausal rat by El‐Tahawy, Nashwa Fathy Gamal, Abdel Hafez, Sara Mohamed Naguib, Ramzy, Maggie M, Zenhom, Nagwa M., Abdel‐Hamid, Heba A.

“…Cerebellum seems to be a specific target for both the decrease of estrogen and hypertension in menopause. The aim of this study was to investigate the…”
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Association of IL‐1β, IL‐1RN, and ESR1 genes polymorphism with risk of infection and response to sofosbuvir plus daclatasvir combination therapy in hepatitis C virus genotype‐4 patients by Khairy, Rasha M., Abdulghany, Hend M., Abdel‐Raheim, Salama, Zenhom, Nagwa M., Abd Elfatah, Aliaa S, Abdalla, Nilly H.

“…Sofosbuvir (SOF) and daclatasvir combination with or without ribavirin proved to be effective and safe in the treatment of hepatitis C virus infection. The…”
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C-peptide corrects hepatocellular dysfunction in a rat model of type 1 diabetes by Abdel-Hamid, Heba A., Abdel-Hakeem, Elshymaa A., Zenhom, Nagwa M., Toni, Nisreen D. M.

“…C-peptide is gaining much interest recently due to its well-documented beneficial effects on multiple organ dysfunction induced by diabetes. Our study was…”
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Role of Nrf2/HO-1 and PI3K/Akt Genes in the Hepatoprotective Effect of Cilostazol by Hassan, Marwa, Ibrahim, Mohamad A, Hafez, Heba M, Mohamed, Mervat Z, Zenhom, Nagwa M, Abd Elghany, Hend M

“…Cilostazol, a phosphodiesterase 3 inhibitor (PDE3I), is a platelet aggregation inhibitor and vasodilator that is useful for treating intermittent claudication…”
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