Search Results - "Zengin Kurt, Belma"
-
1
Synthesis and anticholinesterase activity of novel non-hepatotoxic naphthyridine-11-amine derivatives
Published in Molecular diversity (01-08-2019)“…In the present study, 14 novel naphthyridine-11-amine derivatives were synthesized and their inhibitory effects on acetylcholinesterase (AChE) and…”
Get full text
Journal Article -
2
A novel series of mixed-ligand M(II) complexes containing 2,2′-bipyridyl as potent α-glucosidase inhibitor: synthesis, crystal structure, DFT calculations, and molecular docking
Published in Journal of biological inorganic chemistry (01-08-2019)“…Diabetes mellitus (DM) is a common degenerative disease and characterized by high blood glucose levels. Since the effective antidiabetic treatments attempt to…”
Get full text
Journal Article -
3
Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2017)“…New coumaryl-thiazole derivatives with the acetamide moiety as a linker between the alkyl chains and/or the heterocycle nucleus were synthesized and in vitro…”
Get full text
Journal Article -
4
Glycopolymer decorated multiwalled carbon nanotubes for dual targeted breast cancer therapy
Published in Journal of materials chemistry. B, Materials for biology and medicine (21-04-2020)“…Carbon-based nanomaterials (CNMs) have attracted great attention in biomedical applications such as cancer imaging and therapy. CNMs, which are currently used…”
Get more information
Journal Article -
5
Fungal biotransformation of carvone and camphor by Aspergillus flavus and investigation of cytotoxic activities of naturally obtained essential oils
Published in Natural product research (19-03-2023)“…In this study, the biotransformation of carvone and camphor by Aspergillus flavus and the products were investigated. The biotransformation reaction of carvone…”
Get full text
Journal Article -
6
Synthesis of flurbiprofen thiadiazole urea derivatives and assessment of biological activities and molecular docking studies
Published in Chemical biology & drug design (01-12-2023)“…Totally 15 novel flurbiprofen urea derivatives were synthesized bearing the thiadiazole ring. Their inhibition effects on tyrosinase were determined. 3c was…”
Get full text
Journal Article -
7
Structural and mechanical analysis of three orthodontic adhesive composites cured with different light units
Published in Journal of applied biomaterials & functional materials (2020)“…Objective: To evaluate the effects of three different curing units on the physical and mechanical features of three different orthodontic adhesive resin…”
Get full text
Journal Article -
8
A novel series of M(II) complexes of 6‐methylpyridine‐2‐carboxylic acid with 4(5)methylimidazole: Synthesis, crystal structures, α‐glucosidase activity, density functional theory calculations and molecular docking
Published in Applied organometallic chemistry (01-07-2019)“…Novel complexes of 6‐methylpyridine‐2‐carboxylic acid and 4(5)methylimidazole, namely [Mn(6‐mpa)2(4(5)MeI)2] (1), [Zn(6‐mpa)2(4(5)MeI)2] (2),…”
Get full text
Journal Article -
9
Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2017)“…New coumaryl-carboxamide derivatives with the thiourea moiety as a linker between the alkyl chains and/or the heterocycle nucleus were synthesized and their…”
Get full text
Journal Article -
10
Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies
Published in European journal of medicinal chemistry (01-12-2019)“…Carbonic anhydrases isoforms CA IX, and XII are known to be highly expressed in various human tissues and malignancies. CA IX is a prominent target for…”
Get full text
Journal Article -
11
In situ reduction of graphene oxide by different plant extracts as a green catalyst for selective hydrogenation of nitroarenes
Published in International journal of hydrogen energy (08-10-2019)“…The reduction of graphene oxide (GO) was examined by using the extracts of different plants; cloves, white mulberry, black cumin seed, blackthorn, dark grape,…”
Get full text
Journal Article -
12
Chitosan and carboxymethyl cellulose based magnetic nanocomposites for application of peroxidase purification
Published in International journal of biological macromolecules (01-03-2017)“…Schematic illustration of the fast and facile enrichment protocol for purification of peroxidase by using CH/CMC-Fe3O4 magnetic nanoparticles. [Display…”
Get full text
Journal Article -
13
Synthesis, antioxidant activity and SAR study of novel spiro-isatin-based Schiff bases
Published in Molecular diversity (01-11-2019)“…A new series of 21 Schiff bases of spiro-isatin was synthesized, and their DPPH, CUPRAC and ABTS cation radical scavenging abilities were investigated for…”
Get full text
Journal Article -
14
Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors
Published in Bioorganic chemistry (01-10-2021)“…[Display omitted] •Novel tacrine substituted carbamate derivatives were synthesized.•All compounds inhibited AChE and BuChE at nanomolar level.•Covalent…”
Get full text
Journal Article -
15
Synthesis and biological evaluation of novel coumarin-chalcone derivatives containing urea moiety as potential anticancer agents
Published in Arabian journal of chemistry (01-01-2020)“…The increasing interest on new drug discovery is constantly up to date as drugs do not increase survival adequately against increasing cancer cases worldwide…”
Get full text
Journal Article -
16
Synthesis, cytotoxic evaluation, and in silico studies of novel benzenesulfonamide-thiazolidinone derivatives against colorectal carcinoma
Published in Journal of molecular structure (05-02-2025)“…•Thirteen novel benzenesulfonamide bearing 4-thiazolidinone derivatives were designed and synthesized.•The effects on colorectal cell line were…”
Get full text
Journal Article -
17
Synthesis, antioxidant and anticholinesterase activities of novel coumarylthiazole derivatives
Published in Bioorganic chemistry (01-04-2015)“…[Display omitted] •42 new coumarylthiazole derivatives containing urea/thiourea groups were synthesized.•All the compounds showed inhibitory activities for…”
Get full text
Journal Article -
18
Concentration effects on optical properties, DFT, crystal characterization and α-glucosidase activity studies: Novel Zn(II) complex
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-12-2021)“…[Display omitted] •Novel Zn(II) complex was synthesized and its crystal structure was determined.•The experimental optical properties at different…”
Get full text
Journal Article -
19
Spectrofluorimetric Determination of Aflatoxin B 1 in Winter Herbal Teas via Magnetic Solid Phase Extraction Method by using Metal–Organic Framework (MOF) Hybrid Structures Anchored with Magnetic Nanoparticles
Published in Applied organometallic chemistry (01-03-2020)“…MIL53(Al)‐SiO 2 @Fe 3 O 4 composite was prepared by co‐precipitation route with a typical Stöber synthetic process and ultrasonic‐agitation, then subsequently…”
Get full text
Journal Article -
20
Synthesis of Sorafenib−Ruthenium Complexes, Investigation of Biological Activities and Applications in Drug Delivery Systems as an Anticancer Agent
Published in Journal of medicinal chemistry (28-03-2024)“…Sorafenib, a multiple kinase inhibitor, is widely used as a first-line treatment for hepatocellular carcinoma. However, there is a need for more effective…”
Get full text
Journal Article