Search Results - "Zeng, Xiongzhi"

JZTX-V, a Sodium Channel Inhibitor, Exhibits Excellent Analgesic Effects in Mouse Models by Bo, Chen, Zhenghua, Sun, Xiongzhi, Zeng

“…JZTX-V, an inhibitor of voltage-gated sodium and potassium channels, is derived from the venom of the spider Chilobrachys jingzhao in China. JZTX-V was…”
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Understanding High-Temperature Chemical Reactions on Metal Surfaces: A Case Study on Equilibrium Concentration and Diffusivity of CxHy on a Cu(111) Surface by Li, Pai, Zeng, Xiongzhi, Li, Zhenyu

“…Chemical reactions on metal surfaces are important in various processes such as heterogeneous catalysis and nanostructure growth. At moderate or lower…”
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Molecular mechanism by which spider-driving peptide potentiates coagulation factors by Yuan, Fuchu, Li, Shuwan, Huang, Biao, Hu, Ya, Zeng, Xiongzhi, Peng, Yanmei, Du, Canwei, Rong, Mingqiang

“…Hemostasis is a crucial process that quickly forms clots at injury sites to prevent bleeding and infections. Dysfunctions in this process can lead to…”
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Effects of JZTX-V on the wild type Kv4.3 Expressed in HEK293T and Molecular Determinants in the Voltage-sensing Domains of Kv4.3 Interacting with JZTX-V by Dehong, Xu, Wenmei, Wu, Siqin, Hong, Peng, Zeng, Xianchun, Wang, Xiongzhi, Zeng

“…JZTX-V is a toxin isolated from the venom of the Chinese spider Chilobrachys jingzhao. Previous studies had shown that JZTX-V could inhibit the transient…”
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JZTX-V Targets the Voltage Sensor in Kv4.2 to Inhibit Ito Potassium Channels in Cardiomyocytes by Zhang, Yiya, Luo, Ji, He, Juan, Rong, Mingqiang, Zeng, Xiongzhi

“…Kv4 potassium channels are responsible for transient outward K + currents in the cardiac action potential (AP). Previous experiments by our group demonstrated…”
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Selective Closed-State Nav1.7 Blocker JZTX-34 Exhibits Analgesic Effects against Pain by Zeng, Xiongzhi, Li, Pengpeng, Chen, Bo, Huang, Juan, Lai, Ren, Liu, Jingze, Rong, Mingqiang

“…Jingzhaotoxin-34 (JZTX-34) is a selective inhibitor of tetrodotoxin-sensitive (TTX-S) sodium channels. In this study, we found that JZTX-34 selectively acted…”
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Toxin diversity revealed by a transcriptomic study of Ornithoctonus huwena by Zhang, Yiya, Huang, Yong, He, Quanze, Liu, Jinyan, Luo, Ji, Zhu, Li, Lu, Shanshan, Huang, Pengfei, Chen, Xinyi, Zeng, Xiongzhi, Liang, Songping

“…Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide…”
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Molecular surface of JZTX-V (β-Theraphotoxin-Cj2a) interacting with voltage-gated sodium channel subtype NaV1.4 by Luo, Ji, Zhang, Yiya, Gong, Mengting, Lu, Shanshan, Ma, Yifeng, Zeng, Xiongzhi, Liang, Songping

“…Voltage-gated sodium channels (VGSCs; NaV1.1-NaV1.9) have been proven to be critical in controlling the function of excitable cells, and human genetic evidence…”
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The activation effect of hainantoxin-I, a peptide toxin from the Chinese spider, Ornithoctonus hainana, on intermediate-conductance Ca2+-activated K+ channels by Huang, Pengfei, Zhang, Yiya, Chen, Xinyi, Zhu, Li, Yin, Dazhong, Zeng, Xiongzhi, Liang, Songping

“…Intermediate-conductance Ca2+-activated K+ (IK) channels are calcium/calmodulin-regulated voltage-independent K+ channels. Activation of IK currents is…”
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Isolation and characterization of Jingzhaotoxin-V, a novel neurotoxin from the venom of the spider Chilobrachys jingzhao by Zeng, Xiongzhi, Deng, Meichun, Lin, Ying, Yuan, Chunhua, Pi, Jianhui, Liang, Songping

“…Jingzhaotoxin-V (JZTX-V), a 29-residue polypeptide, is derived from the venom of the spider Chilobrachys jingzhao. Its cDNA determined by rapid amplification…”
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Synthesis and characterization of huwentoxin-IV, a neurotoxin inhibiting central neuronal sodium channels by Xiao, Yucheng, Luo, Xuan, Kuang, Fang, Deng, Meichun, Wang, Meichi, Zeng, Xiongzhi, Liang, Songping

“…Our previous work demonstrated that huwentoxin-IV was an inhibitor cystine knot peptide from Chinese tarantula Ornithoctonus huwena venom that blocked…”
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Jingzhaotoxin-III, a Novel Spider Toxin Inhibiting Activation of Voltage-gated Sodium Channel in Rat Cardiac Myocytes by Xiao, Yucheng, Tang, Jianzhou, Yang, Yuejun, Wang, Meichi, Hu, Weijun, Xie, Jinyun, Zeng, Xiongzhi, Liang, Songping

“…We have isolated a cardiotoxin, denoted jingzhaotoxin-III (JZTX-III), from the venom of the Chinese spider Chilobrachys jingzhao. The toxin contains 36…”
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Jingzhaotoxin-XII, a gating modifier specific for Kv4.1 channels by Yuan, Chunhua, Liao, Zhi, Zeng, Xiongzhi, Dai, Longjun, Kuang, Fang, Liang, Songping

“…Jingzhaotoxin-XII (JZTX-XII), a 29-residue polypeptide, was purified from the venom of the Chinese tarantula Chilobrachys jingzhao. Electrophysiological…”
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Assignment of Disulfide Bonds in HNTX-XXI by Double-Enzymatic Digestion and Edman Degradation by Chen, Bo, He, Juan, Hu, Zhaotun, Zeng, Xiongzhi

“…HNTX-XXI, a peptide toxin derived from the venom of the spider Ornithoctonus hainana, comprises a 64-amino-acid protein architecture that notably incorporates…”
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First-Principles Analysis of the Raman Spectra of 2D Material YbOCl by Zhu, Leilei, Zeng, Xiongzhi, Shang, Honghui, Li, Zhenyu

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Quantum Neural Network Inspired Hardware Adaptable Ansatz for Efficient Quantum Simulation of Chemical Systems by Zeng, Xiongzhi, Fan, Yi, Liu, Jie, Li, Zhenyu, Yang, Jinlong

“…The variational quantum eigensolver is a promising way to solve the Schrödinger equation on a noisy intermediate-scale quantum (NISQ) computer, while its…”
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Molecular mechanisms of two novel and selective TRPV1 channel activators by Chen, Bo, Hu, Zhaotun, Chen, Xinlong, Zeng, Xiongzhi

“…Venomous toxins hold immense value as tools in elucidating the intricate structure and underlying mechanisms of ion channels. In this article, we identified of…”
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Molecular Basis of JZTX-III Inhibiting the Fast Inactivation of Voltage-Gated Sodium Channel Nav1.5 by Chen, Bo, Lu, Min, Zeng, Xiongzhi

“…Prior research has established that Jingzhaotoxin-III (JZTX-III) can selectively target Nav1.5 channels. It achieves this by anchoring the DII-S4 voltage…”
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Hydrocarbon Species on the Cu(111) Surface Studied with a Neural Network Potential by Xu, Sen, Wu, Liling, Fan, Yi, Liu, Yufeng, Zeng, Xiongzhi, Li, Zhenyu

“…Hydrocarbon species are involved in various surface processes, such as graphene growth on Cu surfaces. A systematic examination of their structures, stability,…”
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Toward Epitaxial Growth of Misorientation-Free Graphene on Cu(111) Foils by Sun, Luzhao, Chen, Buhang, Wang, Wendong, Li, Yanglizhi, Zeng, Xiongzhi, Liu, Haiyang, Liang, Yu, Zhao, Zhenyong, Cai, Ali, Zhang, Rui, Zhu, Yeshu, Wang, Yuechen, Song, Yuqing, Ding, Qingjie, Gao, Xuan, Peng, Hailin, Li, Zhenyu, Lin, Li, Liu, Zhongfan

“…The epitaxial growth of single-crystal thin films relies on the availability of a single-crystal substrate and a strong interaction between epilayer and…”
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