Search Results - "Zeng, Veronica"
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698 PD-L1 targeted CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors
Published in Journal for immunotherapy of cancer (01-11-2021)“…BackgroundT cells in the tumor microenvironment require T cell receptor (TCR) /major histocompatibility complex engagement and costimulatory receptor…”
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697 Tumor-targeted CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundT cells in the tumor micro-environment require TCR/MHC engagement and co-stimulatory receptor engagement to achieve complete activation. Solid tumors…”
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Abstract 5654: Affinity tuned Xmab®2+1 anti-mesothelin x anti-CD3 bispecific antibody induces selective T cell-dependent cellular cytotoxicity of human ovarian cancer cells
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Mesothelin (MSLN) is a tumor-associated antigen highly expressed in ovarian tumors. Current treatment options for ovarian cancer have only modest…”
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Abstract 1880: PDL1-targeted CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract T cells in the tumor micro-environment require TCR/MHC engagement and co-stimulatory receptor engagement to achieve complete activation. Tumor cells…”
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IFN-γ-deficient transplant induces acute gut GVHD via dysregulation of RagIIIγ and intestinal microbiota
Published in The Journal of immunology (1950) (01-05-2017)“…Abstract Gut GVHD is critical for determining the outcome of allogenic hematopoietic cell transplantation (HCT). Damage of Paneth cells, loss of defensins, and…”
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Abstract 5663: Affinity tuned XmAb®2+1 PSMA x CD3 bispecific antibodies demonstrate selective activity in prostate cancer models
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Bispecific antibodies enable therapeutic modalities inaccessible to traditional mAbs, such as T cell engagers that bind both CD3 on T cells and a…”
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Abstract 2983: Tumor-specific CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract T cells in the tumor micro-environment require TCR/MHC engagement and co-stimulatory receptor engagement to achieve optimal activation. Solid tumor…”
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