Search Results - "Zeng, Samuel"
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Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy
Published in Nature communications (10-06-2021)“…Targeting tumor-associated macrophages (TAMs) is a promising strategy to modify the immunosuppressive tumor microenvironment and improve cancer immunotherapy…”
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miR‐194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice
Published in Hepatology (Baltimore, Md.) (01-12-2010)“…MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by interacting with the 3′ untranslated region (3′‐UTR) of multiple mRNAs. Recent…”
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Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells
Published in Nature biotechnology (01-12-2014)“…Efficient reprogramming of pancreatic acinar cells in vivo generates cells that mature toward a beta cell phenotype over many months. Direct lineage conversion…”
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Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
Published in Cell reports. Medicine (16-11-2021)“…Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and…”
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Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men: Heterogenous immunity to SARS-CoV-2
Published in Emerging microbes & infections (01-01-2021)“…Background: We studied humoral and cellular responses against SARS-CoV-2 longitudinally in a homogeneous population of healthy young/middle-aged men of South…”
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Off-the-shelf third-party HSC-engineered iNKT cells for ameliorating GvHD while preserving GvL effect in the treatment of blood cancers
Published in iScience (16-09-2022)“…Allo-HSCT is a curative therapy for hematologic malignancies owing to GvL effect mediated by alloreactive T cells; however, the same T cells also mediate GvHD,…”
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The nuclear receptor CAR modulates alcohol-induced liver injury
Published in Laboratory investigation (01-08-2011)“…The constitutive androstane receptor (CAR) is a member of the nuclear receptor superfamily and a sensor and detoxifier of both xenobiotics and endobiotics…”
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Factors influencing SARS-CoV-2 transmission and outbreak control measures in densely populated settings
Published in Scientific reports (27-07-2021)“…Starting with a handful of SARS-CoV-2 infections in dormitory residents in late March 2020, rapid transmission in their dense living environments ensued and by…”
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Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice
Published in Proceedings of the National Academy of Sciences - PNAS (08-12-2020)“…Type 1 diabetes (T1D) results from the autoimmune destruction of β cells, so cure of firmly established T1D requires both reversal of autoimmunity and…”
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Combination Therapy of Allogeneic HSCT and In Vivo Activated iNKT Cells Prevents Acute Gvhd While Augmenting GVL Effect
Published in Blood (13-11-2019)“…Adult acute lymphoblastic leukemia (ALL) is a highly aggressive cancer with poor clinical prognosis and high relapse rate. Whereas allogeneic hematopoietic…”
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Targeting monoamine oxidase A for T cell-based cancer immunotherapy
Published in Science immunology (14-05-2021)“…Monoamine oxidase A (MAO-A) is an enzyme best known for its function in the brain, where it breaks down neurotransmitters and thereby influences mood and…”
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Erratum: Corrigendum: Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells
Published in Nature biotechnology (07-08-2015)Get full text
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Corrigendum: Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells
Published in Nature biotechnology (01-08-2015)Get full text
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Correction: Corrigendum: Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells
Published in Nature biotechnology (2015)“…Nat. Biotechnol. 32, 1223–1230 (2014); published online 17 November 2014; corrected after print 14 May 2015 In the version of this article initially published,…”
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Intermediately Complex Models for the Hydrological Interactions in the Atmosphere-Vegetation-Soil System
Published in Advances in atmospheric sciences (2006)“…This paper investigates the hydrological interactions in the atmosphere-evegetation-soil system by using the bucket model and several new simplified…”
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