Search Results - "Zeng, Qingshu"

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia by Li, June, van der Wal, Dianne E., Zhu, Guangheng, Xu, Miao, Yougbare, Issaka, Ma, Li, Vadasz, Brian, Carrim, Naadiya, Grozovsky, Renata, Ruan, Min, Zhu, Lingyan, Zeng, Qingshu, Tao, Lili, Zhai, Zhi-min, Peng, Jun, Hou, Ming, Leytin, Valery, Freedman, John, Hoffmeister, Karin M., Ni, Heyu

“…Immune thrombocytopenia (ITP) is a common bleeding disorder caused primarily by autoantibodies against platelet GPIIbIIIa and/or the GPIb complex. Current…”
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Chidamide in relapsed or refractory peripheral T cell lymphoma: a multicenter real-world study in China by Shi, Yuankai, Jia, Bo, Xu, Wei, Li, Wenyu, Liu, Ting, Liu, Peng, Zhao, Weili, Zhang, Huilai, Sun, Xiuhua, Yang, Haiyan, Zhang, Xi, Jin, Jie, Jin, Zhengming, Li, Zhiming, Qiu, Lugui, Dong, Mei, Huang, Xiaobing, Luo, Yi, Wang, Xiaodong, Wang, Xin, Wu, Jianqiu, Xu, Jingyan, Yi, Pingyong, Zhou, Jianfeng, He, Hongming, Liu, Lin, Shen, Jianzhen, Tang, Xiaoqiong, Wang, Jinghua, Yang, Jianmin, Zeng, Qingshu, Zhang, Zhihui, Cai, Zhen, Chen, Xiequn, Ding, Kaiyang, Hou, Ming, Huang, Huiqiang, Li, Xiaoling, Liang, Rong, Liu, Qifa, Song, Yuqin, Su, Hang, Gao, Yuhuan, Liu, Lihong, Luo, Jianmin, Su, Liping, Sun, Zimin, Tan, Huo, Wang, Huaqing, Wang, Jingwen, Wang, Shuye, Zhang, Hongyu, Zhang, Xiaohong, Zhou, Daobin, Bai, Ou, Wu, Gang, Zhang, Liling, Zhang, Yizhuo

“…The efficacy and safety of chidamide, a new subtype-selective histone deacetylase (HDAC) inhibitor, have been demonstrated in a pivotal phase II clinical…”
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The successful combination of grapefruit juice and venetoclax in an unfit acute myeloid leukemia patient with adverse risk: A case report by Long, Zhangbiao, Ruan, Min, Wu, Wei, Zeng, Qingshu, Li, Qingsheng, Huang, Zhengqi

“…Venetoclax combined with hypomethylating agents such as azacitidine and decitabine is the standard regime for the elderly patient with acute myeloid leukemia…”
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Platelet desialylation correlates with efficacy of first-line therapies for immune thrombocytopenia by Tao, Lili, Zeng, Qingshu, Li, June, Xu, Miao, Wang, Jiajia, Pan, Ying, Wang, Huiping, Tao, Qianshan, Chen, Yang, Peng, Jun, Hou, Ming, Jansen, Arend Jan Gerard, Ni, Heyu, Zhai, Zhimin

“…Immune thrombocytopenia (ITP) is a common autoimmune bleeding disorder. Despite considerable investigation, the pathogenesis of ITP remains incompletely…”
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Integrated evaluation of hardware and software interfaces for automotive human–machine interaction by Zeng, Qingshu, Jiang, Bing, Duan, Qijun

“…In this work, the authors have developed an integrated evaluation hierarchy for automotive human–machine interaction (HMI) software/hardware interfaces and a…”
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Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies by Zeng, Qingshu, Zhu, Lingyan, Tao, Lili, Bao, Jing, Yang, Mingzhen, Simpson, Elisa K., Li, Conglei, van der Wal, Dianne E., Chen, Pingguo, Spring, Christopher M., Wang, Mingli, Zhang, Lingjie, Ruan, Changgeng, Hou, Ming, Xia, Ruixiang, Ni, Heyu

“…Immune thrombocytopenia (ITP) is characterized by platelet clearance mediated primarily by autoantibodies against the platelet GPIIbIIIa and/or GPIbα. Steroid…”
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Design Framework and Intelligent In-Vehicle Information System for Sensor-Cloud Platform and Applications by Zeng, Qingshu, Duan, Qijun, Shi, Mingxiang, He, Xiangjian, Hassan, Mohammad Mehedi

“…The sensor-cloud system (SCS) integrates sensors, sensor networks, and the cloud for managing sensors, collecting data, and decision-making. Smart…”
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Long Non-coding RNA X-Inactive Specific Transcript Mediates Cell Proliferation and Intrusion by Modulating the miR-497/Bcl-w Axis in Extranodal Natural Killer/T-cell Lymphoma by Liu, Qinhua, Ran, Ruonan, Wu, Zhengsheng, Li, Xiaodan, Zeng, Qingshu, Xia, Ruixiang, Wang, Yalei

“…The present study was directed toward laying new findings for Extranodal natural killer/T-cell lymphoma (ENKL)-oriented therapy with a focus on long non-coding…”
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TIM-3 Expression Level on AML Blasts Correlates With Presence of Core Binding Factor Translocations Rather Than Clinical Outcomes by Hong, Jian, Xia, Leiming, Huang, Zhenqi, Yuan, Xiaodong, Liang, Xinglin, Dai, Jifei, Wu, Zhonghui, Liang, Li, Ruan, Min, Long, Zhangbiao, Cheng, Xin, Chen, Xiaowen, Ni, Jing, Ge, Jian, Li, Qingsheng, Zeng, Qingshu, Xia, Ruixiang, Wang, Yi, Yang, Mingzhen

“…T-cell immunoglobulin and mucin domain-containing molecule 3 (TIM-3) expresses on leukemic stem and progenitor populations of non-M3 acute myeloid leukemia…”
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Quality‐of‐life, mental health, and perspective on TKI dose reduction as a prelude to discontinuation in chronic phase chronic myeloid leukemia by Chen, Yilin, Xu, Na, Yang, Yunfan, Liu, Zhenfang, Xue, Mengxing, Meng, Li, He, Qun, Chen, Chunyan, Zeng, Qingshu, Zhu, Huanling, Du, Xin, Zou, Jing, He, Wenjun, Guo, Jingming, Chen, Suning, Yuan, Guolin, Wu, Hui, Hong, Mei, Cheng, Fanjun, Liu, Bingcheng, Zhang, Yanli, Li, Weiming

“…Background Treatment‐free remission (TFR) has become the main target for chronic myeloid leukemia (CML). Tyrosine kinase inhibitors (TKI) dose optimization is…”
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A Multi-Center, Real-World Study of Chidamide for Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas in China by Liu, Weiping, Zhao, Donglu, Liu, Ting, Niu, Ting, Song, Yongping, Xu, Wei, Jin, Jie, Cai, Qingqing, Huang, Huiqiang, Li, Zhiming, Hou, Ming, Zhang, Huilai, Zhou, Jianfeng, Hu, Jianda, Shen, Jianzhen, Shi, Yuankai, Yang, Yu, Zhang, Liling, Zhao, Weili, Ding, Kaiyang, Qiu, Lugui, Tan, Huo, Zhang, Zhihui, Liu, Lihong, Wang, Jinghua, Xu, Bing, Zhou, Hui, Gao, Guangxun, Xue, Hongwei, Bai, Ou, Feng, Ru, Huang, Xiaobing, Yang, Haiyan, Yan, Xiaojing, Zeng, Qingshu, Liu, Peng, Li, Wenyu, Mao, Min, Su, Hang, Wang, Xin, Xu, Jingyan, Zhou, Daobin, Zhang, Hongyu, Ma, Jun, Shen, Zhixiang, Zhu, Jun

“…Chidamide has demonstrated significant clinical benefits for patients with relapsed/refractory (R/R) PTCL in previous studies. This multi-center observational…”
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Long non-coding RNA CRNDE suppressing cell proliferation is regulated by DNA methylation in chronic lymphocytic leukemia by Ni, Jing, Hong, Jian, Li, Qingsheng, Zeng, Qingshu, Xia, Ruixiang

“…•CRNDE expression is regulated by DNA methylation in chronic lymphocytic leukemia.•CRNDE modulates NDRG2 expression via competitively binding miR-28.•CRNDE…”
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Mutation profile and prognostic relevance in elderly patients with de novo acute myeloid leukemia treated with decitabine‐based chemotherapy by Ni, Jing, Hong, Jian, Long, Zhangbiao, Li, Qingsheng, Xia, Ruixiang, Zeng, Qingshu

“…Introduction Decitabine‐based chemotherapy regimens have shown efficacy in the treatment of elderly patients with acute myeloid leukemia (AML). However, it…”
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Marrow fibrosis is an independent predictor of hematological toxicity of tyrosine kinase inhibitors for the treatment of chronic myeloid leukemia by Ni, Jing, Hong, Jian, Zhang, Zhendong, Li, Qingsheng, Xia, Ruixiang, Zeng, Qingshu, Sun, Guoping

“…Hematological toxicity is a common adverse effect of tyrosine kinase inhibitors (TKIs) for the treatment of chronic myeloid leukemia (CML). We retrospectively…”
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High‐dose dexamethasone plus recombinant human thrombopoietin vs high‐dose dexamethasone alone as frontline treatment for newly diagnosed adult primary immune thrombocytopenia: A prospective, multicenter, randomized trial by Yu, Yafei, Wang, Miaomiao, Hou, Yu, Qin, Ping, Zeng, Qingshu, Yu, Wenzheng, Guo, Xinhong, Wang, Jingxia, Wang, Xiaomin, Liu, Guoqiang, Chu, Xiaoxia, Yang, Lan, Feng, Ying, Zhou, Fang, Sun, Zhaogang, Zhang, Mei, Wang, Xin, Wang, Zhencheng, Ran, Xuehong, Zhao, Hongguo, Wang, Lei, Zhang, Haiyan, Bi, Kehong, Li, Daqi, Yuan, Chenglu, Xu, Ruirong, Wang, Yili, Zhou, Yuhong, Peng, Jun, Liu, Xin‐guang, Hou, Ming

“…We conducted a prospective, multicenter, randomized, controlled clinical trial to compare the efficacy and safety of high‐dose dexamethasone (HD‐DXM) plus…”
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Mechanisms underlying the increased chemosensitivity of bortezomib-resistant multiple myeloma by silencing nuclear transcription factor Snail1 by Huang, Zhenqi, Liang, Xinglin, Wu, Wei, Chen, Xiaowen, Zeng, Qingshu, Yang, Mingzhen, Ge, Jian, Xia, Ruixiang

“…The Snail family transcriptional repressor 1 gene (Snail1) was screened in multiple myeloma cells (MMCs) from bortezomib-resistant MM patients and was found to…”
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A predictive model for therapy failure in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy by Zhang, Xiaoshuai, Liu, Bingcheng, Huang, Jian, Zhang, Yanli, Xu, Na, Gale, Robert Peter, Li, Weiming, Liu, Xiaoli, Zhu, Huanling, Pan, Ling, Yang, Yunfan, Lin, Hai, Du, Xin, Liang, Rong, Chen, Chunyan, Wang, Xiaodong, Li, Guohui, Liu, Zhuogang, Zhang, Yanqing, Liu, Zhenfang, Hu, Jianda, Liu, Chunshui, Li, Fei, Yang, Wei, Meng, Li, Han, Yanqiu, Lin, Li’e, Zhao, Zhenyu, Tu, Chuanqing, Zheng, Caifeng, Bai, Yanliang, Zhou, Zeping, Chen, Suning, Qiu, Huiying, Yang, Lijie, Sun, Xiuli, Sun, Hui, Zhou, Li, Liu, Zelin, Wang, Danyu, Guo, Jianxin, Pang, Liping, Zeng, Qingshu, Suo, Xiaohui, Zhang, Weihua, Zheng, Yuanjun, Huang, Xiaojun, Jiang, Qian

“…•The predictive model stratified CML patients into 3 risk subgroups with significantly different cumulative incidences of TKI-therapy failure. [Display…”
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Comparison of the Efficacy Among Nilotinib, Dasatinib, Flumatinib and Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia Patients: A Real-World Multi-Center Retrospective Study by Zhang, Xiaoshuai, Xu, Na, Yang, Yunfan, Lin, Hai, Liu, Bingcheng, Du, Xin, Liu, Xiaoli, Liang, Rong, Chen, Chunyan, Huang, Jian, Zhu, Huanling, Pan, Ling, Wang, Xiaodong, Li, Guohui, Liu, Zhuogang, Zhang, Yanqing, Liu, Zhenfang, Hu, Jianda, Liu, Chunshui, Li, Fei, Yang, Wei, Meng, Li, Han, Yanqiu, Lin, Li'e, Zhao, Zhenyu, Tu, Chuanqing, Zheng, Caifeng, Bai, Yanliang, Zhou, Zeping, Chen, Suning, Qiu, Huiying, Yang, Lijie, Sun, Xiuli, Sun, Hui, Zhou, Li, Liu, Zelin, Wang, Danyu, Guo, Jianxin, Pang, Liping, Zeng, Qingshu, Suo, Xiaohui, Zhang, Weihua, Zheng, Yuanjun, Zhang, Yanli, Li, Weiming, Jiang, Qian

“…There are limited data comprehensively comparing therapy responses and outcomes among nilotinib, dasatinib, flumatinib and imatinib for newly diagnosed…”
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Baseline Characteristics and Early Monitoring of Chinese CML Patients Treated with Dasatinib: Report from a Multicenter, Observational, Registry-Based Study by Jiang, Qian, Hu, Jianda, Zheng, Fang, Du, Xin, Meng, Li, Wu, Depei, Liu, Bingcheng, Liu, Zhuogang, Ma, Jun, Hou, Ming, Qian, Sixuan, Zeng, Qingshu, Hu, Yu, Huang, Xiaojun

“…Background: Previously, real-world baseline characteristics and response monitoring pattern of Chinese CML patients treated with dasatinib were poorly studied…”
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Chemotherapy-induced alteration of SDF-1/CXCR4 expression in bone marrow-derived mesenchymal stem cells from adolescents and young adults with acute lymphoblastic leukemia by Ge, Jian, Hu, Yan, Gui, Yu, Hou, Ruiqin, Yang, Mingzhen, Zeng, Qingshu, Xia, Ruixiang

“…Bone marrow-derived mesenchymal stem cells (BM-MSCs) in the marrow stroma provide a scaffold for hematopoiesis. Chemokine stromal cell-derived factor-1 (SDF-1)…”
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