Search Results - "Zeng, Baitao"

Full-Length Dystrophin Restoration via Targeted Exon Addition in DMD-Patient Specific iPSCs and Cardiomyocytes by Xiao, Rou, Zhou, Miaojin, Wang, Peiyun, Zeng, Baitao, Wu, Lingqian, Hu, Zhiqing, Liang, Desheng

“…Duchenne muscular dystrophy (DMD) is the most common fatal muscle disease, with an estimated incidence of 1/3500–1/5000 male births, and it is associated with…”
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Seamless Genetic Conversion of SMN2 to SMN1 via CRISPR/Cpf1 and Single-Stranded Oligodeoxynucleotides in Spinal Muscular Atrophy Patient-Specific Induced Pluripotent Stem Cells by Zhou, Miaojin, Hu, Zhiqing, Qiu, Liyan, Zhou, Tao, Feng, Mai, Hu, Qian, Zeng, Baitao, Li, Zhuo, Sun, Qianru, Wu, Yong, Liu, Xionghao, Wu, Lingqian, Liang, Desheng

“…Spinal muscular atrophy (SMA) is a kind of neuromuscular disease characterized by progressive motor neuron loss in the spinal cord. It is caused by mutations…”
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Identification of two novel and one rare mutation in DYRK1A and prenatal diagnoses in three Chinese families with intellectual Disability-7 by Huang, Cheng, Luo, Haiyan, Zeng, Baitao, Feng, Chuanxin, Chen, Jia, Yuan, Huizhen, Huang, Shuhui, Yang, Bicheng, Zou, Yongyi, Liu, Yanqiu

“…Intellectual disability-7 (MRD7) is a subtype disorder of intellectual disability (MRD) involving feeding difficulties, hypoactivity, and febrile seizures at…”
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Prenatal chromosomal microarray analysis in a large Chinese cohort of fetuses with congenital heart defects: a single center study by Lu, Qing, Luo, Laipeng, Zeng, Baitao, Luo, Haiyan, Wang, Xianjin, Qiu, Lijuan, Yang, Yan, Feng, Chuanxin, Zhou, Jihui, Hu, Yanling, Huang, Tingting, Ma, Pengpeng, Huang, Ting, Xie, Kang, Yuan, Huizhen, Huang, Shuhui, Yang, Bicheng, Zou, Yongyi, Liu, Yanqiu

“…Congenital heart defect (CHD) is one of the most common birth defects. The aim of this cohort study was to evaluate the prevalence of chromosomal abnormalities…”
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Damaged DNA Is an Early Event of Neurodegeneration in Induced Pluripotent Stem Cell-Derived Motoneurons with UBQLN2P497H Mutation by Zhang, Yiti, Zeng, Baitao, Gu, Ao, Kang, Qinyu, Zhao, Mingri, Peng, Guangnan, Zhou, Miaojin, Liu, Wanxi, Liu, Min, Ding, Lingjie, Liang, Desheng, Liu, Xionghao, Liu, Mujun

“…Ubiquilin-2 (UBQLN2) mutations lead to familial amyotrophic lateral sclerosis (FALS)/and frontotemporal dementia (FTLD) through unknown mechanisms. The…”
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Identification of five novel SCN1A variants by Zeng, Baitao, Zhang, Haoyi, Lu, Qing, Fu, Qingzi, Yan, Yang, Lu, Wan, Ma, Pengpeng, Feng, Chuanxin, Qin, Jiawei, Luo, Laipeng, Yang, Bicheng, Zou, Yongyi, Liu, Yanqiu

“…Background Epilepsy is characterized by recurrent unprovoked seizures. Mutations in the voltage-gated sodium channel alpha subunit 1 ( SCN1A ) gene are the…”
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Screening and mutation analysis of phenylalanine hydroxylase deficiency in newborns from Jiangxi province by Zeng, Baitao, Lu, Qing, Chen, Shaohong, Guan, Huizhen, Xu, Xiaolan, Zou, Yongyi, Wang, Feng, Huang, Shuhui, Liu, Yanqiu, Yang, Bicheng

“…Phenylalanine hydroxylase deficiency (PAHD) is an autosomal recessive disorder of amino acid metabolism and caused by mutations in the phenylalanine…”
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Mutation spectrum of PTS gene in patients with tetrahydrobiopterin deficiency from jiangxi province by Xie, Kang, Zeng, Baitao, Zhang, Liuyang, Chen, Shaohong, Zou, Yongyi, Yuan, Huizhen, Huang, Shuhui, Wang, Feng, Lu, Qing, Liu, Yanqiu, Yang, Bicheng

“…Hyperphenylalaninemia (HPA) is the most common inborn error in amino acid metabolism. It can be primarily classified into phenylalanine hydroxylase (PAH)…”
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Mesenchymal stem cells derived from iPSCs expressing interleukin-24 inhibit the growth of melanoma in the tumor-bearing mouse model by Wu, Zheng, Liu, Wei, Wang, Zujia, Zeng, Baitao, Peng, Guangnan, Niu, Hongyan, Chen, Linlin, Liu, Cong, Hu, Qian, Zhang, Yuxuan, Pan, Mengmeng, Wu, Lingqian, Liu, Mujun, Liu, Xionghao, Liang, Desheng

“…Interleukin-24 ( - ) is a therapeutic gene for melanoma, which can induce melanoma cell apoptosis. Mesenchymal stem cells (MSCs) show promise as a carrier to…”
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An Episomal CRISPR/Cas12a System for Mediating Efficient Gene Editing by Duan, Nannan, Tang, Shuqing, Zeng, Baitao, Hu, Zhiqing, Hu, Qian, Wu, Lingqian, Zhou, Miaojin, Liang, Desheng

“…(1) Background: Gene editing technology, as represented by CRISPR is a powerful tool used in biomedical science. However, the editing efficiency of such…”
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Reevaluating the splice-altering variant in TECTA as a cause of nonsyndromic hearing loss DFNA8/12 by functional analysis of RNA by Yang, Yan, Luo, Haiyan, Pan, Lijuan, Feng, Chuanxin, Guo, Zhen, Zou, Yongyi, Zeng, Baitao, Huang, Shuhui, Yuan, Huizhen, Wu, Ping, Liu, Danping, Dan, Yi, Xiao, Junfang, Li, XinYu, Chen, ZhongFa, Zeng, Xiao Ni, Jiang, XiangLong, Yang, Bicheng, Liu, Yuhe, Liu, Yanqiu

“…The aim of this study was to determine the genetic cause of early onset autosomal dominant hearing loss segregating in five-generation kindred of Chinese…”
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Targeted addition of mini-dystrophin into rDNA locus of Duchenne muscular dystrophy patient-derived iPSCs by Zeng, Baitao, Zhou, Miaojin, Liu, Bo, Shen, Fei, Xiao, Rou, Su, Jiasun, Hu, Zhiqing, Zhang, Yiti, Gu, Ao, Wu, Lingqian, Liu, Xionghao, Liang, Desheng

“…Duchenne muscular dystrophy (DMD), the most common lethal muscular disorder, affects 1 in 5000 male births. It is caused by mutations in the X-linked…”
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A General-Purpose Device for Interaction with LLMs by Xu, Jiajun, Wang, Qun, Cao, Yuhang, Zeng, Baitao, Liu, Sicheng

“…This paper investigates integrating large language models (LLMs) with advanced hardware, focusing on developing a general-purpose device designed for enhanced…”
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