First experience in the use of a new Russian narcotic analgesic prosidol in oncology

Prosidol, a new Russian narcotic analgesic, was used in various dosage forms (buccal and oral tablets, injection solution) in 113 cancer patients for the treatment of chronic pain, as a component of total anesthesia, and for postoperative analgesia. The best results were attained with the universal...

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Bibliographic Details
Published in:	Anesteziologiia i reanimatologiia no. 4; p. 53
Main Authors:	Osipova, N A, Novikov, G A, Vetsheva, M S, Prokhorov, B M, Beresnev, V A, Loseva, N A, Zemskaia, S Iu, Smolina, T A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-1994
Subjects:	Administration, Buccal Adult Aged Aged, 80 and over Analgesics, Opioid - administration & dosage Analgesics, Opioid - therapeutic use Anesthesia Chronic Disease Female Fentanyl - administration & dosage Fentanyl - therapeutic use Humans Male Middle Aged Neoplasms - physiopathology Pain - drug therapy Pain - etiology Pain, Postoperative - drug therapy Piperidines - administration & dosage Piperidines - therapeutic use Promedol - administration & dosage Promedol - therapeutic use Tramadol - administration & dosage Tramadol - therapeutic use
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Summary:	Prosidol, a new Russian narcotic analgesic, was used in various dosage forms (buccal and oral tablets, injection solution) in 113 cancer patients for the treatment of chronic pain, as a component of total anesthesia, and for postoperative analgesia. The best results were attained with the universal noninvasive dosage form, buccal tablets, used for the treatment of chronic pain in incurable patients. Analgesic properties of buccal prosidol are close to those of tramadol, the drug is well tolerated by the patients and causes no grave side effects. As a drug for postoperative analgesia prosidol was highly effective in patients after extracavitary oncologic surgery and less effective after thoracal and abdominal interventions. As a component of total anesthesia prosidol is inferior to fentanyl and approximately similar to promedol. An advantage of prosidol is its highly effective universal noninvasive dosage form, buccal tablets, which may be used for rapid analgesia in any situation.
ISSN:	0201-7563