Search Results - "Zempel, H."

Laser-Induced Axotomy of Human iPSC-Derived and Murine Primary Neurons Decreases Somatic Tau and AT8 Tau Phosphorylation: A Single-Cell Approach to Study Effects of Acute Axonal Damage by Bell-Simons, M., Buchholz, S., Klimek, J., Zempel, H.

“…The microtubule-associated protein Tau is highly enriched in axons of brain neurons where it regulates axonal outgrowth, plasticity, and transport. Efficient…”
Get full text

Axonal TAU Sorting Requires the C-terminus of TAU but is Independent of ANKG and TRIM46 Enrichment at the AIS by Bell, M., Bachmann, S., Klimek, J., Langerscheidt, F., Zempel, H.

“…•SH-SY5Y-derived neurons are a suitable human cell model for studying TAU sorting.•The N-terminal protein half is not sufficient for anterograde axonal…”
Get full text

A cascade linking A-beta through Tau missorting to destruction of dendritic microtubules by spastin by Zempel, H, Luedtke, J, Mandelkow, Eva Maria

Get full text

S.04.02 Tau, axonal transport and Alzheimer's disease by Mandelkow, E.M, Sydow, A, Hochgräfe, K, Kumar, Y, Zempel, H, Mandelkow, E

Get full text