Search Results - "Zemla, A"

LGA: a method for finding 3D similarities in protein structures by Zemla, Adam

“…We present the LGA (Local-Global Alignment) method, designed to facilitate the comparison of protein structures or fragments of protein structures in sequence…”
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MvirDB--a microbial database of protein toxins, virulence factors and antibiotic resistance genes for bio-defence applications by Zhou, C E, Smith, J, Lam, M, Zemla, A, Dyer, M D, Slezak, T

“…Knowledge of toxins, virulence factors and antibiotic resistance genes is essential for bio-defense applications aimed at identifying 'functional' signatures…”
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MvirDB--a microbial database of protein toxins, virulence factors and antibiotic resistance genes for bio-defence applications by Zhou, C.E, Smith, J, Lam, M, Zemla, A, Dyer, M.D, Slezak, T

“…Knowledge of toxins, virulence factors and antibiotic resistance genes is essential for bio-defense applications aimed at identifying 'functional' signatures…”
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Highly similar structural frames link the template tunnel and NTP entry tunnel to the exterior surface in RNA-dependent RNA polymerases by Lang, Dorothy M, Zemla, A T, Zhou, C L Ecale

“…RNA-dependent RNA polymerase (RdRp) is essential to viral replication and is therefore one of the primary targets of countermeasures against these dangerous…”
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Stage of bladder cancer in Central Europe - Polish perspective by Poletajew, S, Biernacki, R, Buraczynski, P, Chojnacki, J, Czarniecki, S, Gajewska, D, Pohaba, T, Sondka, J, Skrzypczyk, M, Suchojad, T, Wojtkowiak, D, Zaforemski, B, Zapala, L, Zemla, A, Radziszewski, P

“…Mortality rate from bladder cancer in Europe is the highest in its Central Region. This study is an attempt to find underlying factors by proper…”
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P1223 E2216 … A PROMISING DRUG LEAD THAT INHIBITS HCV INFECTIVITY THROUGH TARGETING HCV E2 by Al Olaby, R.R, Azzazy, H, Dubuisson, J, Cocquerel, L, Saas, L, Vielmetter, J, Forli, S, Marcotrigiano, J, Khan, A.G, Whidby, J, Zemla, A, Balhorn, R

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AS2TS system for protein structure modeling and analysis by Zemla, A., Zhou, C. Ecale, Slezak, T., Kuczmarski, T., Rama, D., Torres, C., Sawicka, D., Barsky, D.

“…We present a set of programs and a website designed to facilitate protein structure comparison and protein structure modeling efforts. Our protein structure…”
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Bovine enterovirus 2: complete genomic sequence and molecular modelling of a reference strain and a wild-type isolate from endemically infected US cattle by Goens, S.D, Botero, S, Zemla, A, Ecale Zhou, C, Perdue, M.L

“…Bovine enteroviruses are members of the family Picornaviridae, genus Enterovirus. Whilst little is known about their pathogenic potential, they are apparently…”
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On the Fundamental Solutions for the Difference Helmholtz Operator by Zemla, Adam

“…In this paper we construct the difference approximation of the Helmholtz operator on a square grid and we analyze asymptotic properties of the difference…”
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Antibody Elbow Angles are Influenced by their Light Chain Class by Stanfield, Robyn L., Zemla, Adam, Wilson, Ian A., Rupp, Bernhard

“…We have examined the elbow angles for 365 different Fab fragments, and observe that Fabs with λ light chains have adopted a wider range of elbow angles than…”
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Computational approaches for identification of conserved/unique binding pockets in the A chain of ricin by Zhou, Carol L. Ecale, Zemla, Adam T., Roe, Diana, Young, Malin, Lam, Marisa, Schoeniger, Joseph S., Balhorn, Rod

“…Motivation: Specific and sensitive ligand-based protein detection assays that employ antibodies or small molecules such as peptides, aptamers or other small…”
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Rapid development of nucleic acid diagnostics by Fitch, J.P., McCready, P.M., Gardner, S.N., Kuczmarski, T.A., Kurtz, S., Myers, R., Ott, L.L., Slezak, T.R., Vitalis, E.A., Zemla, A.T.

“…There has been a significant increase, fueled by technologies front the human genome project, in the availability of nucleic acid sequence information for…”
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Critical assessment of methods of protein structure prediction (CASP)-round V by Moult, John, Fidelis, Krzysztof, Zemla, Adam, Hubbard, Tim

“…This article provides an introduction to the special issue of the journal Proteins dedicated to the fifth CASP experiment to assess the state of the art in…”
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A modified definition of Sov, a segment-based measure for protein secondary structure prediction assessment by Zemla, Adam, Venclovas, Česlovas, Fidelis, Krzysztof, Rost, Burkhard

“…We present a measure for the evaluation of secondary structure prediction methods that is based on secondary structure segments rather than individual…”
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StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase by Zemla, A, Lang, D, Kostova, T, Andino, R, Zhou, C

“…Most of the currently used methods for protein function prediction rely on sequence-based comparisons between a query protein and those for which a functional…”
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Assessment of progress over the CASP experiments by Venclovas, C̆eslovas, Zemla, Adam, Fidelis, Krzysztof, Moult, John

“…The quality of structure models produced in the CASP5 experiment has been compared with that in earlier CASPs. The most significant progress is in the fold…”
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A study of quality measures for protein threading models by Cristobal, S, Zemla, A, Fischer, D, Rychlewski, L, Elofsson, A

“…Prediction of protein structures is one of the fundamental challenges in biology today. To fully understand how well different prediction methods perform, it…”
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Processing and analysis of CASP3 protein structure predictions by Zemla, Adam, Venclovas, Česlovas, Moult, John, Fidelis, Krzysztof

“…Livermore Prediction Center provides basic infrastructure for the CASP (Critical Assessment of Structure Prediction) experiments, including prediction…”
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Practical Applications of Structural Genomics Technologies for Mutagen Research by Zemla, A, Segelke, B

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Processing and evaluation of predictions in CASP4 by Zemla, Adam, Venclovas, Česlovas, Moult, John, Fidelis, Krzysztof

“…The Livermore Prediction Center conducted the target collection and prediction submission processes for Critical Assessment of Protein Structure Prediction…”
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