Search Results - "Zellweger, Raphaël M."

Enhanced infection of liver sinusoidal endothelial cells in a mouse model of antibody-induced severe dengue disease by Zellweger, Raphaël M, Prestwood, Tyler R, Shresta, Sujan

“…Dengue virus (DENV) causes disease ranging from dengue fever (DF), a self-limited febrile illness, to the potentially lethal dengue hemorrhagic fever and…”
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A Protective Role for Dengue Virus-Specific CD8+ T Cells by Yauch, Lauren E, Zellweger, Raphael M, Kotturi, Maya F, Qutubuddin, Afrina, Sidney, John, Peters, Bjoern, Prestwood, Tyler R, Sette, Alessandro, Shresta, Sujan

“…Infection with one of the four serotypes of dengue virus (DENV1-4) can result in a range of clinical manifestations in humans, from dengue fever to the more…”
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Role of humoral versus cellular responses induced by a protective dengue vaccine candidate by Zellweger, Raphaël M, Miller, Robyn, Eddy, William E, White, Laura J, Johnston, Robert E, Shresta, Sujan

“…With 2.5 billion people at risk, dengue is a major emerging disease threat and an escalating public health problem worldwide. Dengue virus causes disease…”
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CD8+ T cells prevent antigen-induced antibody-dependent enhancement of dengue disease in mice by Zellweger, Raphaël M, Eddy, William E, Tang, William W, Miller, Robyn, Shresta, Sujan

“…Dengue virus (DENV) causes pathologies ranging from the febrile illness dengue fever to the potentially lethal severe dengue disease. A major risk factor for…”
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Socioeconomic and environmental determinants of dengue transmission in an urban setting: An ecological study in Nouméa, New Caledonia by Zellweger, Raphaël M, Cano, Jorge, Mangeas, Morgan, Taglioni, François, Mercier, Alizé, Despinoy, Marc, Menkès, Christophe E, Dupont-Rouzeyrol, Myrielle, Nikolay, Birgit, Teurlai, Magali

“…Dengue is a mosquito-borne virus that causes extensive morbidity and economic loss in many tropical and subtropical regions of the world. Often present in…”
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A current perspective on antimicrobial resistance in Southeast Asia by Zellweger, Raphaël M, Carrique-Mas, Juan, Limmathurotsakul, Direk, Day, Nicholas P J, Thwaites, Guy E, Baker, Stephen

“…Southeast Asia, a vibrant region that has recently undergone unprecedented economic development, is regarded as a global hotspot for the emergence and spread…”
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CD8+ T Cells Can Mediate Short-Term Protection against Heterotypic Dengue Virus Reinfection in Mice by Zellweger, Raphaël M, Tang, William W, Eddy, William E, King, Kevin, Sanchez, Marisa C, Shresta, Sujan

“…Dengue virus (DENV) is a major public health threat worldwide. Infection with one of the four serotypes of DENV results in a transient period of protection…”
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Gamma Interferon (IFN-γ) Receptor Restricts Systemic Dengue Virus Replication and Prevents Paralysis in IFN-α/β Receptor-Deficient Mice by PRESTWOOD, Tyler R, MORAR, Malika M, ZELLWEGER, Raphaël M, MILLER, Robyn, MAY, Monica M, YAUCH, Lauren E, LADA, Steven M, SHRESTA, Sujan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination by Yauch, Lauren E, Prestwood, Tyler R, May, Monica M, Morar, Malika M, Zellweger, Raphaël M, Peters, Bjoern, Sette, Alessandro, Shresta, Sujan

“…The contribution of T cells to the host response to dengue virus (DENV) infection is not well understood. We previously demonstrated a protective role for…”
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Vaccination against SARS-CoV-2 and disease enhancement - knowns and unknowns by Zellweger, Raphaël M, Wartel, T Anh, Marks, Florian, Song, Manki, Kim, Jerome H

“…The world is currently fighting a COVID-19 pandemic, perhaps the most disruptive infectious disease outbreak since the 1918 Spanish influenza. Governments have…”
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CAPTURA Regional Workshop Proceedings (28–30 June 2022, Virtual) by Joh, Hea Sun, Dolabella, Brooke, Early, Emmanuel, Stelling, John, Ak, Gabriella, Upadhyaya, Madan Kumar, Rahman, Aninda, Chuki, Pem, MacWright, William R, Ondoa, Pascale, Sarkar, Satyajit, Moore, Catrin, Holm, Marianne, Leslie, Toby, Zellweger, Raphaël M, Paing, Giyoung, Kwon, Soo Young, Marks, Florian, Poudyal, Nimesh

“…Abstract In response to the global threat of antimicrobial resistance (AMR), the Capturing Data on Antimicrobial Resistance Patterns and Trends in Use in…”
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A 23-year retrospective investigation of Salmonella Typhi and Salmonella Paratyphi isolated in a tertiary Kathmandu hospital by Zellweger, Raphaël M, Basnyat, Buddha, Shrestha, Poojan, Prajapati, Krishna G, Dongol, Sabina, Sharma, Paban K, Koirala, Samir, Darton, Thomas C, Dolecek, Christiane, Thompson, Corinne N, Thwaites, Guy E, Baker, Stephen G, Karkey, Abhilasha

“…Salmonella serovars Typhi (S. Typhi) and Paratyphi A (S. Paratyphi A), the causative agents of enteric fever, have been routinely isolated organisms from the…”
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A Mouse-Passaged Dengue Virus Strain with Reduced Affinity for Heparan Sulfate Causes Severe Disease in Mice by Establishing Increased Systemic Viral Loads by PRESTWOOD, Tyler R, PRIGOZHIN, Daniil M, SHARAR, Kristin L, ZELLWEGER, Raphaël M, SHRESTA, Sujan

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Serology as a Tool to Assess Infectious Disease Landscapes and Guide Public Health Policy by Haselbeck, Andrea H., Im, Justin, Prifti, Kristi, Marks, Florian, Holm, Marianne, Zellweger, Raphaël M.

“…Understanding the local burden and epidemiology of infectious diseases is crucial to guide public health policy and prioritize interventions. Typically,…”
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Typhoid Control in an Era of Antimicrobial Resistance: Challenges and Opportunities by Vanderslott, Samantha, Kumar, Supriya, Adu-Sarkodie, Yaw, Qadri, Firdausi, Zellweger, Raphaël M

“…Abstract Historically, typhoid control has been achieved with water and sanitation interventions. Today, in an era of rising antimicrobial resistance (AMR),…”
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Mouse models to study dengue virus immunology and pathogenesis by Zellweger, Raphaël M, Shresta, Sujan

“…The development of a compelling murine model of dengue virus (DENV) infection has been challenging, because DENV clinical isolates do not readily replicate or…”
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Disentangling etiologies of CNS infections in Singapore using multiple correspondence analysis and random forest by Zellweger, Raphaël M., Yacoub, Sophie, Chan, Yvonne F. Z., Soon, Derek, Shafi, Humaira, Ooi, Say Tat, Chan, Monica, Jacobson, Leslie, Sessions, October M., Vincent, Angela, Low, Jenny Guek Hong, Ooi, Eng Eong, Wang, Linfa, Wijaya, Limin, Tan, Kevin

“…Central nervous system (CNS) infections cause substantial morbidity and mortality worldwide, with mounting concern about new and emerging neurologic…”
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Antibody effector analysis of prime versus prime-boost immunizations with a recombinant measles-vectored chikungunya virus vaccine by Tschismarov, Roland, Zellweger, Raphaël M, Koh, Min Jie, Leong, Yan Shan, Low, Jenny G, Ooi, Eng Eong, Mandl, Christian W, Ramsauer, Katrin, de Alwis, Ruklanthi

“…Chikungunya is a mosquito-borne disease that causes periodic but explosive epidemics of acute disease throughout the tropical world. Vaccine development…”
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Genomic signature of early T-cell response is associated with lower antibody titer threshold for sterilizing immunity by Ong, Eugenia Z., Gan, Esther S., de Alwis, Ruklanthi, Wijaya, Limin, Ong, Xin Mei, Zhang, Menglan, Wong, Abigail WL, Cheung, Yin Bun, Zellweger, Raphaël M., Ooi, Eng Eong, Low, Jenny G.

“…Vaccination is an effective approach to reduce disease burden. High vaccination coverage blocks pathogen transmission to ensure herd immunity. However, the…”
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Systemic inflammation, innate immunity and pathogenesis after Zika virus infection in cynomolgus macaques are modulated by strain-specificity within the Asian lineage by de Alwis, Ruklanthi, Zellweger, Raphaël M., Chua, Edmond, Wang, Lin-Fa, Chawla, Tanu, Sessions, October M., Marlier, Damien, Connolly, John E., von Messling, Veronika, Anderson, Danielle E.

“…Zika virus (ZIKV) is an emerging arbovirus with recent global expansion. Historically, ZIKV infections with Asian lineages have been associated with mild…”
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