Search Results - "Zellner, Katie"

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps by Marx, Charlotte, Novotny, Julia, Salbeck, Danby, Zellner, Katie R., Nicolai, Leo, Pekayvaz, Kami, Kilani, Badr, Stockhausen, Sven, Bürgener, Niklas, Kupka, Danny, Stocker, Thomas J., Weckbach, Ludwig T., Pircher, Joachim, Moser, Markus, Joner, Michael, Desmet, Walter, Adriaenssens, Tom, Neumann, Franz-Josef, Gerschlick, Anthony H., ten Berg, Jurrien M., Lorenz, Michael, Stark, Konstantin

“…Clinical observations implicate a role of eosinophils in cardiovascular diseases because markers of eosinophil activation are elevated in atherosclerosis and…”
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Eosinophils regulate dendritic cells and Th2 pulmonary immune responses following allergen provocation by Jacobsen, Elizabeth A, Zellner, Katie R, Colbert, Dana, Lee, Nancy A, Lee, James J

“…Reports have recently suggested that eosinophils have the potential to modulate allergen-dependent pulmonary immune responses. The studies presented expand…”
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Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease by Uderhardt, Stefan, Ackermann, Jochen A, Fillep, Tobias, Hammond, Victoria J, Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R, Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L, Lee, James J, Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B, Krönke, Gerhard

“…Blood coagulation is essential for physiological hemostasis but simultaneously contributes to thrombotic disease. However, molecular and cellular events…”
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Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red” by Lee, James J., PhD, Jacobsen, Elizabeth A., PhD, Ochkur, Sergei I., PhD, McGarry, Michael P., PhD, Condjella, Rachel M., PhD, Doyle, Alfred D., BS, Luo, Huijun, PhD, Zellner, Katie R., BS, Protheroe, Cheryl A., BA, Willetts, Lian, BS, LeSuer, William E., BS, Colbert, Dana C., MS, Helmers, Richard A., MD, Lacy, Paige, PhD, Moqbel, Redwan, PhD, FRCPath, Lee, Nancy A., PhD

“…The respective life histories of human subjects and mice are well defined and describe a unique story of evolutionary conservation extending from sequence…”
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Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation by Jacobsen, Elizabeth A, Ochkur, Sergei I, Doyle, Alfred D, LeSuer, William E, Li, Wen, Protheroe, Cheryl A, Colbert, Dana, Zellner, Katie R, Shen, HuaHao H, Irvin, Charles G, Lee, James J, Lee, Nancy A

“…The release of eosinophil granule proteins in the lungs of patients with asthma has been dogmatically linked with lung remodeling and airway…”
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In vivo imaging of epithelial wound healing in the cnidarian Clytia hemisphaerica demonstrates early evolution of purse string and cell crawling closure mechanisms by Kamran, Zach, Zellner, Katie, Kyriazes, Harry, Kraus, Christine M, Reynier, Jean-Baptiste, Malamy, Jocelyn E

“…All animals have mechanisms for healing damage to the epithelial sheets that cover the body and line internal cavities. Epithelial wounds heal either by cells…”
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Lifitegrast ophthalmic solution for treatment of ocular chronic graft-versus-host disease by Chhabra, Saurabh, Jerkins, James H., Conto, John E., Zellner, Katie, Shah, Nirav N., Hari, Parameswaran N., Hamadani, Mehdi

“…Ocular chronic graft-versus-host disease (oGVHD) is a relatively common complication that occurs following allogeneic hematopoietic cell transplantation…”
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Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice by Lee, James J., PhD, Protheroe, Cheryl A., BA, Luo, Huijun, PhD, Ochkur, Sergei I., PhD, Scott, Gregory D., BS, Zellner, Katie R., MS, Raish, Randall J., MS, Dahl, Mark V., MD, Vega, Miriam L., MD, MPH, Conley, Olivia, Condjella, Rachel M., PhD, Kloeber, Jake A, Neely, Joseph L, Patel, Yash S, Maizer, Patty, MS, Mazzolini, Andrew, MA, Fryer, Allison D., PhD, Jacoby, Noah W, Jacoby, David B., MD, Lee, Nancy A., PhD

“…Background Contact toxicant reactions are accompanied by localized skin inflammation and concomitant increases in site-specific itch responses. The role(s) of…”
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Frontline Science: Eosinophil‐deficient MBP‐1 and EPX double‐knockout mice link pulmonary remodeling and airway dysfunction with type 2 inflammation by Ochkur, Sergei I., Doyle, Alfred D., Jacobsen, Elizabeth A., LeSuer, William E., Li, Wen, Protheroe, Cheryl A., Zellner, Katie R., Colbert, Dana, Shen, HuaHao H., Irvin, Charlie G., Lee, James J., Lee, Nancy A.

“…Eosinophil‐deficient MBP‐1 and EPX double‐knockout mice show how eosinophils are necessary for increased IL‐4/IL‐13 expression linked with acute and chronic…”
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Cys-leukotrienes promote fibrosis in a mouse model of eosinophil-mediated respiratory inflammation by Ochkur, Sergei I, Protheroe, Cheryl A, Li, Wen, Colbert, Dana C, Zellner, Katie R, Shen, Hua-Hao, Luster, Andrew D, Irvin, Charles G, Lee, James J, Lee, Nancy A

“…Leukotrienes (i.e., products of the 5-lipoxygenase pathway) are thought to be contributors to lung pathologies. Moreover, eosinophils have been linked with…”
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Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease by Uderhardt, Stefan, Ackermann, Jochen A, Fillep, Tobias, Hammond, Victoria J, Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R, Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L, Lee, James J, Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B, Krönke, Gerhard

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Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice by Willetts, Lian, Felix, Lindsey C., Jacobsen, Elizabeth A., Puttagunta, Lakshmi, Condjella, Rachel M., Zellner, Katie R., Ochkur, Sergei I., Kim, John D., Luo, Huijun, Lee, Nancy A., Lee, James J., Moqbel, Redwan, Lacy, Paige

“…Eosinophil degranulation is a determining factor in allergy-mediated airway pathology. Receptor-mediated degranulation in eosinophils requires…”
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Development of a Clinical Lab Assay for Assessment of Eosinophil Peroxidase in Sputum by Ochkur, Sergei I., PhD, Protheroe, Cheryl A, Zellner, Katie R, Colbert, Dana C, Lee, Nancy A., PhD, Nair, Parameswaran K., MD, PhD, FRCP, FRCPC, Lee, James J., PhD

“…Rationale Asthma management strategies based on easy to perform assays representative of surrogate metrics of pulmonary eosinophils (e.g., exhaled nitric oxide…”
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Differential Exposure of Eosinophils to Cytokines Leads to an Activated Phenotype in the Airways Inducing Pulmonary IL-13 Responses That Are Eosinophil Dependent by Jacobsen, Elizabeth A., PhD, Colbert, Dana C, Zellner, Katie R, Protheroe, Cheryl A, LeSuer, William E, Lee, Nancy A., PhD, Lee, James J., PhD

“…Mice deficient (CCR3-/-, IL-5-/-) or devoid (PHIL, δdblGATA-1, IL-5-/-eotaxin-1-/-) of eosinophils display reduced pulmonary IL-13 in various mouse models of…”
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The SNARE VAMP-7 Contributes To Eosinophil Degranulation, In Vivo by Lacy, Paige, Dr, Willetts, Lian, Dr, Jacobsen, Elizabeth, Dr, Condjella, Rachel, Dr, Zellner, Katie, Ms, Ochkur, Sergei, Dr, Lou, Hui, Mr, LeSuer, Will, Mr, Kim, John, Mr, Protheroe, Cheryl, Ms, Pero, Ralph, Mr, Lee, James J., Dr, Lee, Nancy A., Dr, Moqbel, Redwan, Dr

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CHARACTERIZATION AND MANAGEMENT OF CUTANEOUS REACTIONS IN PATIENTS WITH RELAPSED OR REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA TREATED WITH LONCASTUXIMAB TESIRINE IN THE LOTIS-2 TRIAL by Pruett, Julie, Zellner, Katie, Kahl, Brad, Ungar, David, Wang, Luqiang, Hamadani, Mehdi

“…Loncastuximab tesirine (loncastuximab tesirine-lypl; Lonca), an FDA-approved antibody drug conjugate comprising a GDi9-targeted antibody conjugated to a…”
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Clinical activity of ibrutinib in classical Hodgkin lymphoma relapsing after allogeneic stem cell transplantation is independent of tumor BTK expression by Badar, Talha, Astle, John, Kakar, Imran K., Zellner, Katie, Hari, Parameswaran N., Hamadani, Mehdi

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Assessment of 2-Year Storage Conditions on Protein, RNA, and DNA in Unstained Human Tissue Sections, Including a Novel Multiplex Digital Gene Expression Profiling Method with Implications for Biobanking by Ramsower, Colleen, Wisner, Lee, Zellner, Katie, Glinsmann-Gibson, Betty, Larsen, Brandon, McGrath, Michael, Maguire, Alanna, Rimsza, Lisa

“…Formalin-fixed, paraffin-embedded (FFPE) tissues are a valuable resource for clinical and basic science research. Paraffin blocks and the resulting unstained…”
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Outcomes of Grade 3A Follicular Lymphoma: Best Treated As Aggressive or Indolent Lymphoma? by Epperla, Narendranath, Fenske, Timothy S., Olteanu, Horatiu, Pruett, Julie, Goff, Areyl, Zellner, Katie, Hamadani, Mehdi, Shah, Nirav N.

“…Introduction Follicular lymphoma (FL) is the most common form of indolent non-Hodgkin lymphoma in the United States. Although one disease, the histology,…”
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Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice by Jacobsen, E. A., LeSuer, W. E., Willetts, L., Zellner, K. R., Mazzolini, K., Antonios, N., Beck, B., Protheroe, C., Ochkur, S. I., Colbert, D., Lacy, P., Moqbel, R., Appleton, J., Lee, N. A., Lee, J. J.

“…Background The importance and specific role(s) of eosinophils in modulating the immune/inflammatory phenotype of allergic pulmonary disease remain to be…”
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