Search Results - "Zellner, J L"

Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy by THOMAS, C. V, COKER, M. L, ZELLNER, J. L, HANDY, J. R, CRUMBLEY, A. J, SPINALE, F. G

“…One of the hallmarks of dilated cardiomyopathy (DCM) is left ventricular (LV) remodeling. The matrix metalloproteinases (MMPs) are a family of enzymes that…”
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Collagen remodeling and changes in LV function during development and recovery from supraventricular tachycardia by Spinale, F G, Tomita, M, Zellner, J L, Cook, J C, Crawford, F A, Zile, M R

“…Chronic supraventricular tachycardia (SVT) causes left ventricular (LV) dYsfunction and dilatation. Termination of SVT appears to improve symptoms of…”
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Relation Between Ventricular and Myocyte Remodeling With the Development and Regression of Supraventricular Tachycardia-Induced Cardiomyopathy by Spinale, Francis G, Zellner, James L, Tomita, Masaaki, Crawford, Fred A, Zile, Michael R

“…Chronic supraventricular tachycardia (SVT) causes left ventricular (LV) dilatation and dysfunction. Termination of SVT appears to reduce LV size and improve…”
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Alterations in Myocyte Shape and Basement Membrane Attachment With Tachycardia-Induced Heart Failure by Zellner, James L, Spinale, Francis G, Eble, Diane M, Hewett, Kenneth W, Crawford, Fred A

“…Chronic supraventricular tachycardia (SVT) results in left ventricular (LV) dilatation and dysfunction. However, the underlying mechanisms responsible for LV…”
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A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure by SPINALE, Francis G, COKER, Mytsi L, HEUNG, Lena J, BOND, Brian R, GUNASINGHE, Himali R, ETOH, Takuma, GOLDBERG, Aron T, ZELLNER, James L, CRUMBLEY, A. Jackson

“…Matrix metalloproteinases (MMPs) contribute to matrix remodeling in disease states such as tumor metastases. Extracellular matrix metalloproteinase inducer…”
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Isolated left ventricular myocyte contractility in patients undergoing cardiac operations by New, R.Brent, Zellner, James L., Hebbar, Latha, Mukherjee, Rupak, Sampson, Angela C., Hendrick, Jennifer W., Handy, John R., Crawford, Fred, Spinale, Francis G.

“…Background: Because of methods required for obtaining isolated left ventricular myocytes, evaluation of the contractile function of isolated left ventricular…”
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Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target by Spinale, F G, Coker, M L, Bond, B R, Zellner, J L

“…A fundamental structural event in the progression of heart failure due to dilated cardiomyopathy is left ventricular (LV) myocardial remodeling. The matrix…”
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β-Adrenergic and endothelin receptor interaction in dilated human cardiomyopathic myocardium by Walker, C.Allyson, Ergul, Adviye, Grubbs, Ashley, Zile, Michael R., Zellner, James L., Crumbley, A.Jackson, Spinale, Francis G.

“…Background: Although end-stage dilated cardiomyopathy (DCM) is characterized by defects in β-adrenergic receptor (β-AR) activity and increased endothelin-1…”
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Endothelin receptor pathway in human left ventricular myocytes: relation to contractility by Goldberg, Aron T, Bond, Brian R, Mukherjee, Rupak, New, R.Brent, Zellner, James L, Crawford, Fred A, Spinale, Francis G

“…Background. Increased synthesis and release of the potent bioactive peptide endothelin-1 (ET-1) occurs during and after cardiac surgery. However, the cellular…”
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Pneumoperitoneum to Treat Air Leaks and Spaces After a Lung Volume Reduction Operation by Handy, John R, Judson, Marc A, Zellner, James L

“…Lung volume reduction surgery is an option for the management of end-stage emphysema. The most frequent surgical complication of lung volume reduction is…”
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Thermodilution right ventricular ejection fraction. Catheter positioning effects by Spinale, F G, Zellner, J L, Mukherjee, R, Ferris, S E, Crawford, F A

“…Right ventricular (RV) ejection fractions have been difficult to estimate clinically. It has been demonstrated recently that RV ejection fractions can be…”
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Tachycardia-induced cardiomyopathy: effects on blood flow and capillary structure by Spinale, F G, Zellner, J L, Tomita, M, Tempel, G E, Crawford, F A, Zile, M R

“…Chronic supraventricular tachycardia (SVT) causes a dilated cardiomyopathy. A potential factor contributing to the development of SVT-induced cardiomyopathy is…”
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Cardiopulmonary bypass in a gravid patient: perioperative changes in endothelin levels by Zellner, James L, Kribbs, Scott B, Dorman, B.Hugh, Spinale, Francis G

“…Transient elevations of the potent vasoconstrictive peptide endothelin have been reported to occur with the institution of cardiopulmonary bypass. We measured…”
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Chronic amlodipine treatment during the development of heart failure by SPINALE, F. G, MUKHERJEE, R, KROMBACH, R. S, CLAIR, M. J, HENDRICK, J. W, HOUCK, W. V, HEBBAR, L, KRIBBS, S. B, ZELLNER, J. L, DODD, M. G

“…This study examined the effects of chronic amlodipine treatment on left ventricular (LV) pump function, systemic hemodynamics, neurohormonal status, and…”
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Temporal Relation of ATP-Sensitive Potassium-Channel Activation and Contractility Before Cardioplegia by Hebbar, Latha, Houck, Ward V., Zellner, James L., Dorman, B.Hugh, Spinale, Francis G.

“…Background. Pharmacologic treatment using potassium-channel openers (PCOs) before cardioplegic arrest has been demonstrated to provide beneficial effects on…”
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Placement considerations for measuring thermodilution right ventricular ejection fractions by Spinale, F G, Zellner, J L, Mukherjee, R, Crawford, F A

“…Clinical examination of right ventricular (RV) performance has been hampered by the inability to measure easily RV volumes and ejection fraction. This study…”
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Arterial hemorrhage complicating pancreatic pseudocysts: role of angiography by Adams, D B, Zellner, J L, Anderson, M C

“…Major arterial hemorrhage associated with pancreatic pseudocysts represents a formidable complication with high mortality rates. This study was undertaken to…”
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Reducing cardiac surgical trauma : The minimally invasive direct coronary artery bypass by FISHMAN, R. L, HARVEY, S. C, ZELLNER, J. L, PINOSKY, M, HANDY, J. R

“…The concept of minimal surgical trauma is revolutionizing many surgical subspecialties, including cardiac surgery. Coronary artery revascularization can now be…”
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Early and long-term results of coronary artery bypass grafting in dialysis patients by Franga, Dion L, Kratz, John M, Crumbley, A.Jackson, Zellner, James L, Stroud, Martha R, Crawford, Fred A

“…Background. Dialysis patients frequently present with debilitating coronary artery disease but are regarded as challenging patients for coronary artery bypass…”
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Contributory mechanisms for the beneficial effects of myocyte preconditioning during cardioplegic arrest by O, S.-J, ZELLNER, J. L, COX, M. H, HEBBAR, L, BROTHERS, T. E, MUKHERJEE, R, TEMPEL, G. E, DORMAN, B. H, CRAWFORD, F. A, SPINALE, F. G

“…Preconditioning protects the myocardium from ischemia and may be a potent means of endogenous cardioprotection during cardioplegic arrest and rewarming…”
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