Search Results - "Zeller, Matthias W.G"
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Mouse model of anti-NMDA receptor post–herpes simplex encephalitis
Published in Neurology : neuroimmunology & neuroinflammation (01-03-2019)“…OBJECTIVETo develop an endogenous rodent model of postinfectious anti-NMDA receptor (NMDAR) encephalitis. METHODSSix mice were inoculated intranasally with…”
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Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis
Published in Journal of neuroimmunology (15-10-2015)“…Abstract Gelsolin is the fourth most abundant protein in the body and its depletion in the blood has been found in multiple sclerosis (MS) patients. How…”
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A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales
Published in Theranostics (01-01-2019)“…Aberrant innate immune response drives the pathophysiology of many diseases. Myeloperoxidase (MPO) is a highly oxidative enzyme secreted by activated myeloid…”
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Myeloperoxidase-Hepatocyte-Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic Steatohepatitis
Published in Antioxidants & redox signaling (01-12-2015)“…Myeloperoxidase (MPO), a highly oxidative enzyme secreted by leukocytes has been implicated in human and experimental nonalcoholic steatohepatitis (NASH), but…”
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An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-2019)“…Myeloperoxidase (MPO) is a critical proinflammatory enzyme implicated in cardiovascular, neurological, and rheumatological diseases. Emerging therapies…”
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Endothelial receptor proteins in acute venous thrombosis and delayed thrombus resolution in cerebral sinus vein thrombosis
Published in Journal of neurology (01-07-2024)“…Background and purpose Cerebral sinus venous thrombosis (CSVT) is a rare but life-threatening disease and its diagnosis remains challenging. Blood biomarkers,…”
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Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction
Published in International journal of molecular sciences (01-03-2023)“…Myeloperoxidase (MPO) is a highly oxidative, pro-inflammatory enzyme involved in post-myocardial infarction (MI) injury and is a potential therapeutic target…”
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Dabigatran in Cerebral Sinus Vein Thrombosis and Thrombophilia
Published in Life (Basel, Switzerland) (28-06-2022)“…Background and Purpose: Thrombophilic gene alterations are a major risk factor for cerebral sinus vein thrombosis (CSVT). Up to 30% of all patients with…”
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