Search Results - "Zelent, A."

Unlocking the potential of retinoic acid in anticancer therapy by Schenk, T, Stengel, S, Zelent, A

“…All- trans -retinoic acid (ATRA) is a physiologically active metabolite of vitamin A. Its antitumour activities have been extensively studied in a variety of…”
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Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells by Sbirkov, Y, Schenk, T, Kwok, C, Stengel, S, Brown, R, Brown, G, Chesler, L, Zelent, A, Fuchter, M J, Petrie, K

“…All- -retinoic acid (ATRA)-based differentiation therapy of acute promyelocytic leukemia (APL) represents one of the most clinically effective examples of…”
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Acute leukemia in adult Hispanic Americans: a large-population study by Swords, R, Sznol, J, Elias, R, Watts, J, Zelent, A, Martin, E, Vargas, F, Bethel-Ellison, S, Kobetz, E

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Origins and evolutionary diversification of the nuclear receptor superfamily by Owen, G I, Zelent, A

“…Nuclear receptors (NRs), which include those for steroid and thyroid hormones as well as retinoids, are encoded by a large gene superfamily that has evolved to…”
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Deregulated expression of HDAC9 in B-cells promotes development of lymphoproliferative disease and lymphoma by Gil, V. S., Bhagat, G., Howell, L., Zhang, J., Kim, C. H., Stengel, S., Vega, F., Zelent, A., Petrie, K.

“…Histone Deacetylase 9 (HDAC9) is expressed in B-cells and its overexpression has been observed in B-lymphoproliferative disorders and B-cell non-Hodgkin…”
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Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene by DAVIES, J. M, HAWE, N, ZELENT, A, KABAROWSKI, J, HUANG, Q.-H, ZHU, J, BRAND, N. J, LEPRINCE, D, DHORDAIN, P, COOK, M, MORRISS-KAY, G

“…BTB/POZ-domain C2H2 zinc(Zn)-finger proteins are encoded by a subfamily of genes related to the Drosophila gap gene krüppel. To date, two such proteins, PLZF…”
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A Third Human Retinoic Acid Receptor, hRAR-γ by Krust, A., Ph. Kastner, Petkovich, M., Zelent, A., Chambon, P.

“…Retinoic acid receptors (RARs) are retinoic acid (RA)-inducible enhancer factors belonging to the superfamily of steroid/thyroid nuclear receptors. We have…”
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Histone deacetylase inhibitors in APL and beyond by Petrie, K, Prodromou, N, Zelent, A

“…In recent years the study of chemical modifications to chromatin and their effects on cellular processes has become increasingly important in the field of…”
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Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters by Petrie, K, Guidez, F, Zhu, J, Howell, L, Owen, G, Chew, Y P, Parks, S, Waxman, S, Licht, J, Mittnacht, S, Zelent, A

“…Translocations of the retinoic acid receptor-α ( RARα ) locus with the promyelocytic leukemia zinc-finger ( PLZF ) or PML genes lead to expression of oncogenic…”
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Fusion between a novel Krüppel‐like zinc finger gene and the retinoic acid receptor‐alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia by Chen, Z., Brand, N.J., Chen, A., Chen, S.J., Tong, J.H., Wang, Z.Y., Waxman, S., Zelent, A.

“…We have identified a unique case of acute promyelocytic leukaemia (APL) with a t(11;17) reciprocal chromosomal translocation involving the retinoic acid…”
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Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing by Zelent, A, Mendelsohn, C, Kastner, P, Krust, A, Garnier, J. M, Ruffenach, F, Leroy, P, Chambon, P

“…Using anchored PCR, three different cDNA isoforms of the mouse retinoic acid receptor beta [mRAR‐beta 1, mRAR‐beta 2 (formerly mRAR‐beta 0) and mRAR‐beta 3],…”
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Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein by Guidez, Fabien, Petrie, Kevin, Ford, Anthony M., Lu, Huafeng, Bennett, Caroline A., MacGregor, Angus, Hannemann, Jürgen, Ito, Yoshiaki, Ghysdael, Jacques, Greaves, Mel, Wiedemann, Leanne M., Zelent, Arthur

“…The t(12;21)(p13;q22) chromosomal translocation is the most frequent illegitimate gene recombination in a pediatric cancer and occurs in approximately 25% of…”
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Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid by Leroy, P, Krust, A, Zelent, A, Mendelsohn, C, Garnier, J. M, Kastner, P, Dierich, A, Chambon, P

“…Together with the previously described mouse retinoic acid receptor alpha‐1 (mRAR‐alpha 1, formerly mRAR‐alpha 0), we have isolated and characterized here a…”
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Clinical and Molecular Characterization of a Rare Syndrome of Acute Promyelocytic Leukemia Associated With Translocation (11; 17) by Licht, Jonathan D., Chomienne, Christine, Goy, Andre, Chen, Alex, Scott, Amy A., Head, David R., Michaux, Jean Louis, Wu, Yu, DeBlasio, Anthony, Miller, Wilson H., Zelenetz, Andrew D., Willman, Cheryl L., Chen, Zhu, Chen, Sai-Juan, Zelent, A., Macintyre, Elizabeth, Veil, Agnes, Cortes, Jorge, Kantarjian, Hagop, Waxman, Samuel

“…Analysis of a variant translocation t(11; 17) in a case of acute promyelocytic leukemia (APL) led to discovery of a novel zinc finger gene, PLZF, fused to the…”
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PCR cloning of N-terminal RAR isoforms and APL-associated PLZF-RAR alpha fusion proteins by Zelent, A

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Hot on the TRAIL of acute promyelocytic leukemia by Zelent, Arthur

“…The ability of all-trans-retinoic acid to stimulate granulocytic differentiation makes it useful in the treatment of acute promyelocytic leukemia. Recent…”
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Distinct Leukemia Phenotypes in Transgenic Mice and Different Corepressor Interactions Generated by Promyelocytic Leukemia Variant Fusion Genes PLZF-RARα and NPM-RARα by G.-X. Cheng, X.-H. Zhu, X.-Q. Men, Wang, L., Q.-H. Huang, Jin, X. L., S.-M. Xiong, Zhu, J., W.-M. Guo, J.-Q. Chen, S.-F. Xu, So, E., L.-C. Chan, Waxman, S., Zelent, A., G.-Q. Chen, Dong, S., J.-X. Liu, S.-J. Chen

“…Acute promyelocytic leukemia (APL) is characterized by a specific chromosome translocation involving RARα and one of four fusion partners: PML, PLZF, NPM, and…”
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Murine Isoforms of Retinoic Acid Receptor γ with Specific Patterns of Expression by Ph. Kastner, Krust, A., Mendelsohn, C., Garnier, J. M., Zelent, A., Leroy, P., Staub, A., Chambon, P.

“…We have characterized seven murine retinoic acid receptor γ cDNA isoforms (mRAR-γ1 to-γ7) generated by alternative splicing of at least seven exons. These…”
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The effect of antisense inhibition of urokinase receptor in human squamous cell carcinoma on malignancy by Kook, Y.H., Adamski, J., Zelent, A., Ossowski, L.

“…Concomitant expression of urokinase type plasminogen activator (uPA) and its surface receptor (uPAR) has been shown to correlate strongly with a more invasive…”
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Replicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virions by SELLS, M. A, ZELENT, A. Z, SHVARTSMAN, M, ACS, G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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