Search Results - "Zekai HALICI"

Ameliorative effect of gossypin against acute lung injury in experimental sepsis model of rats by Cinar, Irfan, Sirin, Busra, Aydin, Pelin, Toktay, Erdem, Cadirci, Elif, Halici, Iclal, Halici, Zekai

“…Sepsis is a complex pathophysiological event involving systemic inflammatory response syndrome, multiple organ dysfunction syndrome and tissue damage such as…”
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A novel effect of Aprepitant: Protection for cisplatin-induced nephrotoxicity and hepatotoxicity by Un, Harun, Ugan, Rustem Anil, Kose, Duygu, Bayir, Yasin, Cadirci, Elif, Selli, Jale, Halici, Zekai

“…Cisplatin is widely used chemotherapeutic drug and have some serious side effects as tissue toxicity and nausea and vomiting. Aprepitant is used in clinic as…”
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Sepsis and Septic Shock: Current Treatment Strategies and New Approaches by Polat, Gizem, Ugan, Rustem Anil, Cadirci, Elif, Halici, Zekai

“…Sepsis is a complex condition characterized by the simultaneous activation of inflammation and coagulation in response to microbial insult. These events…”
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Phloretin and phloridzin guard against cisplatin-induced nephrotoxicity in mice through inhibiting oxidative stress and inflammation by Un, Harun, Ugan, Rustem Anil, Gurbuz, Muhammet Ali, Bayir, Yasin, Kahramanlar, Aysenur, Kaya, Gokce, Cadirci, Elif, Halici, Zekai

“…Cisplatin (Cis) is widely used chemotherapeutic and has some serious side effects as nephrotoxicity. Phloretin (PH) and Phloridzin (PZ) are known their…”
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A Review of Melatonin, Its Receptors and Drugs by Emet, Mucahit, Ozcan, Halil, Ozel, Lutfu, Yayla, Muhammed, Halici, Zekai, Hacimuftuoglu, Ahmet

“…After a Turkish scientist took Nobel Prize due to his contributions to understand clock genes, melatonin, closely related to these genes, may begin to shine…”
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Investigation of the Role of Stimulation and Blockade of 5-HT7 Receptors in Ketamine Anesthesia by Dincer, Busra, Halici, Zekai, Cadirci, Elif

“…Although several pieces of evidence have indicated the ability of the serotonin-7 receptor (5-HTR 7 ) to modulate N-methyl- D -aspartate receptor (NMDAR)…”
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5-HT7 receptors as a new target for prostate cancer physiopathology and treatment: an experimental study on PC-3 cells and FFPE tissues by Cinar, Irfan, Sirin, Busra, Halici, Zekai, Palabiyik-Yucelik, Saziye Sezin, Akpinar, Erol, Cadirci, Elif

“…Prostate cancer (PCa) is one of the most common types of cancer seen among men worldwide. Previous studies have demonstrated that serotonin regulates cell…”
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The effects of Beeswax, Olive oil and Butter impregnated bandage on burn wound healing by Bayir, Yasin, Un, Harun, Ugan, Rustem Anil, Akpinar, Erol, Cadirci, Elif, Calik, Ilknur, Halici, Zekai

“…•Beeswax–olive oil–butter (BOB) impregnated bandage treatment can enhance wound healing in a second-degree burn rat model.•BOB impregnated bandage treatment…”
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Different Mechanisms in Formation and Prevention of Indomethacin-induced Gastric Ulcers by Suleyman, Halis, Albayrak, Abdulmecit, Bilici, Mehmet, Cadirci, Elif, Halici, Zekai

“…Indomethacin is an indol derivative, non-steroidal, anti-inflammatory drug with anti-inflammatory, analgesic, and antipyretic effects. Indomethacin became the…”
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Liver 5-HT7 receptors: A novel regulator target of fibrosis and inflammation-induced chronic liver injury in vivo and in vitro by Polat, Beyzagul, Halici, Zekai, Cadirci, Elif, Karakus, Emre, Bayir, Yasin, Albayrak, Abdulmecit, Unal, Deniz

“…Hepatocellular cancer (HCC) is the sixth most common cancer and liver fibrosis is strongly associated with HCC. Treatment options are limited, and preventive…”
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Evaluation of 5-HT7 Receptor Trafficking on In Vivo and In Vitro Model of Lipopolysaccharide (LPS)-Induced Inflammatory Cell Injury in Rats and LPS-Treated A549 Cells by Ayaz, Gulsen, Halici, Zekai, Albayrak, Abdulmecit, Karakus, Emre, Cadirci, Elif

“…This study aimed to investigate the effects of the 5-HT7 receptor agonist (LP44) and antagonist (SB269970) on LPS-induced in vivo tissue damage and cell…”
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Can aprepitant used for nausea and vomiting be good gastrointestinal complaints? by Ugan, Rustem Anil, Un, Harun, Kose, Duygu, Cadirci, Elif, Bal Tastan, Tugba, Yayla, Muhammed, Halici, Zekai

“…Aprepitant is a selective SP/NK-1 receptor antagonist and used in postoperative and chemotherapeutics induced emesis and vomiting. The aim of our study is to…”
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Protective effects of melatonin receptor agonists on endotoxin-induced uveitis in rats by Yuksel, Tugba Nurcan, Yayla, Muhammed, Kose, Duygu, Halici, Zekai, Bozkurt, Erdinc, Toktay, Toktay

“…Melatonin has an important role in regulating a variety of physiological functions of the body. We investigated the protective effects of Agomelatine (AGO) and…”
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Effects of Nintedanib on the Lungs via NLRP3 in a Model of Lipopolysaccharide-induced Acute Lung Injury in Rats by TANRİVERDİYEVA, Gulchin, AYDIN, Pelin, TOKTAY, Erdem, ÇADIRCI, Elif, HALICI, Zekai

“…Aim: To demonstrate the possible protective efficacy of nintedanib, a tyrosine kinase inhibitor with demonstrated antifibrotic and antitumor activity, in a…”
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Roflumilast as a Potential Therapeutic Agent for Cecal Ligation and Puncture-Induced Septic Lung Injury by Bayraktutan, Zafer, Dincer, Busra, Keskin, Halil, Kose, Duygu, Bilen, Arzu, Toktay, Erdem, Sirin, Busra, Halici, Zekai

“…This study focused on delineating the possible effects of roflumilast (ROF), a selective phosphodiesterase 4 (PDE4) inhibitor, in rats with cecal ligation and…”
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Early administration of milrinone ameliorates lung and kidney injury during sepsis in juvenile rats by Keskin, Halil, Tavaci, Taha, Halici, Hamza, Yuksel, Tugba Nurcan, Ozkaraca, Mustafa, Bilen, Arzu, Kose, Duygu, Mendil, Ali Sefa, Halici, Zekai

“…Background A sepsis model was created, induced by cecal ligation and puncture (CLP), in juvenile rat groups. Milrinone (MIL), which is known to have a…”
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Evaluation of the Roflumilast Effect Supplemented with Linezolid in Pleural Empyema in Rats Caused by Intrapleural Staphylococcus aureus Inoculation by Kerget, Buğra, Araz, Ömer, Kerget, Ferhan, Erol, Hüseyin Serkan, Özmen, Sevilay, Halıcı, Zekai, Akgün, Metin

“…In addition to tube drains, pleural empyema is treated with antibiotics and anti-inflammatory drugs. We aimed to evaluate the anti-inflammatory activity of…”
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Protective effects of montelukast on ischemia-reperfusion injury in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation by Oral, Akgun, M.D, Odabasoglu, Fehmi, Ph.D, Halici, Zekai, M.D, Keles, Osman Nuri, M.Sc, Unal, Bunyami, M.D., Ph.D, Coskun, A. Kagan, M.D, Kilic, Cenk, M.D, Surer, İlhami, M.D, Salman, A.B., M.D

“…Objective To reveal the effects of montelukast as an antioxidant and tissue protective agent and study the biochemical and histopathologic changes in…”
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Effect of trimetazidine against ovarian ischemia/reperfusion injury in rat model: A new pathway: JAK2/STAT3 by Yuksel, Tugba Nurcan, Halici, Zekai, Cadirci, Elif, Toktay, Erdem, Ozdemir, Bengül, Bozkurt, Ayşe

“…Objective(s): Ovarian ischemia/reperfusion (I/R) is an extremely complex pathological problem that begins with oxygen deprivation, progresses to excessive free…”
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Effects of Aliskiren, an RAAS inhibitor, on a carrageenan-induced pleurisy model of rats by Bayir, Yasin, Un, Harun, Cadirci, Elif, Akpinar, Erol, Diyarbakir, Busra, Calik, Ilknur, Halici, Zekai

“…Our aim is to investigate the potentially preventive effects of Aliskiren in a carrageenan-induced lung pleurisy model and to compare the standard…”
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