Search Results - "Zeinert, Rilee"

The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress by Zeinert, Rilee D., Baniasadi, Hamid, Tu, Benjamin P., Chien, Peter

“…During proteotoxic stress, bacteria maintain critical processes like DNA replication while removing misfolded proteins, which are degraded by the Lon protease…”
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Proteomic survey of the DNA damage response in Caulobacter crescentus by Tashjian, Tommy F, Zeinert, Rilee D, Eyles, Stephen J, Chien, Peter

“…The bacterial DNA damage response is a critical, coordinated response to endogenous and exogenous sources of DNA damage. Response dynamics are dependent on…”
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LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria by Yang, Qiyuan, Liu, Pengpeng, Anderson, Nadine S., Shpilka, Tomer, Du, YunGuang, Naresh, Nandhitha Uma, Li, Rui, Zhu, Lihua Julie, Luk, Kevin, Lavelle, Josh, Zeinert, Rilee D., Chien, Peter, Wolfe, Scot A., Haynes, Cole M.

“…The accumulation of deleterious mitochondrial DNA (∆mtDNA) causes inherited mitochondrial diseases and ageing-associated decline in mitochondrial functions…”
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Degradation of Lon in Caulobacter crescentus by Barros, Benjamin B, Mahmoud, Samar A, Chien, Peter, Zeinert, Rilee D

“…Protein degradation is an essential process in all organisms. This process is irreversible and energetically costly; therefore, protein destruction must be…”
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Protease regulation and capacity during Caulobacter growth by Vass, Robert H, Zeinert, Rilee D, Chien, Peter

“…Highlights • An adaptor hierarchy controls staged protein degradation during cell cycle progression. • ClpXP balances dynamics of replication sliding clamps by…”
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Model-based identification of conditionally-essential genes from transposon-insertion sequencing data by Sarsani, Vishal, Aldikacti, Berent, He, Shai, Zeinert, Rilee, Chien, Peter, Flaherty, Patrick

“…The understanding of bacterial gene function has been greatly enhanced by recent advancements in the deep sequencing of microbial genomes. Transposon insertion…”
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The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter by Woldemeskel, Selamawit Abi, Daitch, Allison K, Alvarez, Laura, Panis, Gaël, Zeinert, Rilee, Gonzalez, Diego, Smith, Erika, Collier, Justine, Chien, Peter, Cava, Felipe, Viollier, Patrick H, Goley, Erin D

“…Bacterial growth and division require regulated synthesis of the macromolecules used to expand and replicate components of the cell. Transcription of…”
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Large Roles of Small Proteins by Burton, Aisha T, Zeinert, Rilee, Storz, Gisela

“…Bacterial proteins of ≤50 amino acids, denoted small proteins or microproteins, have been traditionally understudied and overlooked, as standard computational,…”
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Live‐Cell Imaging of Guanosine Tetra‐ and Pentaphosphate (p)ppGpp with RNA‐based Fluorescent Sensors by Sun, Zhining, Wu, Rigumula, Zhao, Bin, Zeinert, Rilee, Chien, Peter, You, Mingxu

“…Guanosine tetra‐ and pentaphosphate, (p)ppGpp, are important alarmone nucleotides that regulate bacterial survival in stressful environment. A direct detection…”
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Lon recognition of the replication initiator DnaA requires a bipartite degron by Liu, Jing, Zeinert, Rilee, Francis, Laura, Chien, Peter

“…Summary DnaA initiates chromosome replication in bacteria. In Caulobacter crescentus, the Lon protease degrades DnaA to coordinate replication with nutrient…”
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Structure–function analysis of manganese exporter proteins across bacteria by Zeinert, Rilee, Martinez, Eli, Schmitz, Jennifer, Senn, Katherine, Usman, Bakhtawar, Anantharaman, Vivek, Aravind, L., Waters, Lauren S.

“…Manganese (Mn) is an essential trace nutrient for organisms because of its role in cofactoring enzymes and providing protection against reactive oxygen species…”
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Structure‐function analysis of MntP and other manganese exporter proteins and their contribution to reactive oxygen species survival by Martinez, Eli, Zeinert, Rilee, Schmitz, Jennifer, Draven, Joseph, Waters, Lauren

“…Abstract only Manganese is an important trace nutrient involved in the detoxification of reactive oxygen species (ROS). Manganese also acts as an enzyme…”
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An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation by Lariviere, Patrick J., Mahone, Christopher R., Santiago-Collazo, Gustavo, Howell, Matthew, Daitch, Allison K., Zeinert, Rilee, Chien, Peter, Brown, Pamela J.B., Goley, Erin D.

“…Bacterial growth and division require insertion of new peptidoglycan (PG) into the existing cell wall by PG synthase enzymes. Emerging evidence suggests that…”
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EstG is a novel esterase required for cell envelope integrity in Caulobacter by Daitch, Allison K., Orsburn, Benjamin C., Chen, Zan, Alvarez, Laura, Eberhard, Colten D., Sundararajan, Kousik, Zeinert, Rilee, Kreitler, Dale F., Jakoncic, Jean, Chien, Peter, Cava, Felipe, Gabelli, Sandra B., Goley, Erin D.

“…Proper regulation of the bacterial cell envelope is critical for cell survival. Identification and characterization of enzymes that maintain cell envelope…”
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Live‐Cell Imaging of Guanosine Tetra‐ and Pentaphosphate (p)ppGpp with RNA‐based Fluorescent Sensors by Sun, Zhining, Wu, Rigumula, Zhao, Bin, Zeinert, Rilee, Chien, Peter, You, Mingxu

“…Guanosine tetra‐ and pentaphosphate, (p)ppGpp, are important alarmone nucleotides that regulate bacterial survival in stressful environment. A direct detection…”
Get full text