Search Results - "Zein, Claudia O"

Smoking and severity of hepatic fibrosis in nonalcoholic fatty liver disease by Zein, Claudia O, Unalp, Aynur, Colvin, Ryan, Liu, Yao-Chang, McCullough, Arthur J

“…Background & Aims Although many predictors of disease severity of nonalcoholic fatty liver disease (NAFLD) have been proposed, studies of the potential effects…”
Get full text

Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: New evidence on the potential therapeutic mechanism by Zein, Claudia O., Lopez, Rocio, Fu, Xiaoming, Kirwan, John P., Yerian, Lisa M., McCullough, Arthur J., Hazen, Stanley L., Feldstein, Ariel E.

“…Pentoxifylline (PTX) improved the histological features of nonalcoholic steatohepatitis (NASH) in a recent randomized placebo‐controlled trial. However, the…”
Get full text

Prevalence of Hypothyroidism in Nonalcoholic Fatty Liver Disease by Pagadala, Mangesh R., Zein, Claudia O., Dasarathy, Srinivasan, Yerian, Lisa M., Lopez, Rocio, McCullough, Arthur J.

“…Background A possible association between nonalcoholic fatty liver disease (NAFLD) and hypothyroidism has been suggested. The recognized link between…”
Get full text

Clearing the smoke in chronic liver diseases by Zein, Claudia O.

Get full text

A Pilot Trial of Pentoxifylline in Nonalcoholic Steatohepatitis by ADAMS, Leon A, ZEIN, Claudia O, ANGULO, Paul, LINDOR, Keith D

“…Tumor necrosis factor alpha (TNF alpha) contributes to liver damage and insulin resistance among patients with nonalcoholic steatohepatitis (NASH)…”
Get full text

Smoking and increased severity of hepatic fibrosis in primary biliary cirrhosis: A cross validated retrospective assessment by Zein, Claudia O., Beatty, Kristi, Post, Anthony B., Logan, Laurie, Debanne, Sara, McCullough, Arthur J.

“…An epidemiological association between cigarette smoking and primary biliary cirrhosis (PBC) has been demonstrated. Our aim was to determine the relationship…”
Get full text

Primary Sclerosing Cholangitis by Zein, Claudia O., MD, MSc

“…Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease characterized by multifocal strictures of intra and extrahepatic bile…”
Get full text

Clinical Significance of Metabolic Syndrome in the Setting of Chronic Hepatitis C Virus Infection by Hanouneh, Ibrahim A, Feldstein, Ariel E, Lopez, Rocio, Yerian, Lisa, Pillai, Anjana, Zein, Claudia O, Zein, Nizar N

“…Background & Aims: The metabolic syndrome (MS) is a unique condition in which the underlying mechanism is related to insulin resistance. In hepatitis C virus…”
Get full text

Predictors of Steatohepatitis and Advanced Fibrosis in Non-Alcoholic Fatty Liver Disease by Pagadala, Mangesh, MD, Zein, Claudia O., MD, MSc, McCullough, Arthur J., MD

“…Non-alcoholic fatty liver disease is the most common cause of chronic liver disease in the United States. The development of non-alcoholic steatohepatitis…”
Get full text

Pentoxifylline improves nonalcoholic steatohepatitis: A randomized placebo‐controlled trial by Zein, Claudia O., Yerian, Lisa M., Gogate, Prema, Lopez, Rocio, Kirwan, John P., Feldstein, Ariel E., McCullough, Arthur J.

“…The primary aim of this study was to compare the effects of pentoxifylline (PTX) versus placebo on the histological features of nonalcoholic steatohepatitis…”
Get full text

Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis by Kowdley, Kris V., Bowlus, Christopher L., Levy, Cynthia, Akarca, Ulus S., Alvares-da-Silva, Mario Reis, Andreone, Pietro, Arrese, Marco, Corpechot, Christophe, Francque, Sven M., Heneghan, Michael A., Invernizzi, Pietro, Jones, David, Kruger, Frederik C., Lawitz, Eric, Mayo, Marlyn J., Shiffman, Mitchell L., Swain, Mark G., Valera, José Miguel, Vargas, Victor, Vierling, John M., Villamil, Alejandra, Addy, Carol, Dietrich, Julie, Germain, Jean-Michel, Mazain, Sarah, Rafailovic, Dragutin, Taddé, Bachirou, Miller, Benjamin, Shu, Jianfen, Zein, Claudia O., Schattenberg, Jörn M.

“…In a trial involving patients with primary biliary cholangitis, treatment with elafibranor, a dual PPAR-α and PPAR-δ agonist, led to greater improvements in…”
Get full text

Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease by Neuschwander‐Tetri, Brent A., Clark, Jeanne M., Bass, Nathan M., Van Natta, Mark L., Unalp‐Arida, Aynur, Tonascia, James, Zein, Claudia O., Brunt, Elizabeth M., Kleiner, David E., McCullough, Arthur J., Sanyal, Arun J., Diehl, Anna Mae, Lavine, Joel E., Chalasani, Naga, Kowdley, Kris V.

“…The Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) was formed to conduct multicenter studies on the etiology, contributing factors, natural…”
Get full text

Chronic Hepatitis C and Type II Diabetes Mellitus: A Prospective Cross-Sectional Study by ZEIN, Claudia O, LEVY, Cynthia, BASU, Ananda, ZEIN, Nizar N

“…An epidemiologic link between chronic hepatitis C (HCV) and type II diabetes mellitus (DM) has been established. Our aims were to prospectively determine the…”
Get full text

Diabetes Mellitus Is Associated with Impaired Response to Antiviral Therapy in Chronic Hepatitis C Infection by Elgouhari, Hesham M, Zein, Claudia O, Hanouneh, Ibrahim, Feldstein, Ariel E, Zein, Nizar N

“…Insulin resistance may promote hepatic fibrosis in chronic hepatitis C (HCV) and has emerged as a cofactor in failure to achieve sustained viral response…”
Get full text

Alendronate improves bone mineral density in primary biliary cirrhosis : A randomized placebo-controlled trial by ZEIN, Claudia O, JORGENSEN, Roberta A, CLARKE, Bart, WENGER, Doris E, KEACH, Jill C, ANGULO, Paul, LINDOR, Keith D

“…Bone loss is a well-recognized complication of primary biliary cirrhosis (PBC). Although it has been suggested that alendronate might improve bone mineral…”
Get full text

Prevalence and predictors of esophageal varices in patients with primary sclerosing cholangitis by Zein, Claudia O., Lindor, Keith D., Angulo, Paul

“…Patients with primary sclerosing cholangitis (PSC) may develop and bleed from esophageal varices. However, the exact prevalence of esophageal varices in…”
Get full text

Reply to: “Smoking and NASH: A hidden message from the GREACE trial” by Zein, Claudia O, McCullough, Arthur J, Unalp, Aynur

Get full text

Spontaneous clearance of chronic hepatitis C during pregnancy by Zein, Claudia O, Abu-Lebdeh, Haitham, Zein, Nizar N

Get full text

Prevalence and Predictors of Esophageal Varices in Patients With Primary Biliary Cirrhosis by Levy, Cynthia, Zein, Claudia O, Gomez, Justin, Soldevila–Pico, Consuelo, Firpi, Roberto, Morelli, Giuseppe, Nelson, David

“…Background & Aims: Esophageal varices and bleeding are among the most feared complications of primary biliary cirrhosis (PBC). We aimed to determine the…”
Get full text

Clinical Significance of Hepatic Iron Deposition and Serum Iron Values in Patients with Chronic Hepatitis C Infection by METWALLY, Mohamed A, ZEIN, Claudia O, ZEIN, Nizar N

“…To assess the potential association between hepatic iron deposition or serum iron values and hepatic fibrosis and inflammatory activity in patients with…”
Get full text