Search Results - "Zeilmaker, M.J."

Transfer of perfluorooctane sulfonic acid (PFOS) from contaminated feed to dairy milk by van Asselt, E.D., Kowalczyk, J., van Eijkeren, J.C.H., Zeilmaker, M.J., Ehlers, S., Fürst, P., Lahrssen-Wiederholt, M., van der Fels-Klerx, H.J.

“…•A PBPK model was derived describing uptake of PFOS from contaminated fodder into consumption milk.•Almost all PFOS is eliminated through the milk.•PFOS…”
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Carry-over of pyrrolizidine alkaloids from feed to milk in dairy cows by Hoogenboom, L.A.P, Mulder, P.P.J, Zeilmaker, M.J, van den Top, H.J, Remmelink, G.J, Brandon, E.F.A, Klijnstra, M, Meijer, G.A.L, Schothorst, R, Van Egmond, H.P

“…Pyrrolizidine alkaloids are toxins present in many plants belonging to the families of Asteraceae, Boraginaceae and Fabaceae. Particularly notorious are…”
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A novel source for dioxins present in recycled fat from gelatin production by Hoogenboom, L.A.P., Van Eijkeren, J.C.H., Zeilmaker, M.J., Mengelers, M.J.B., Herbes, R., Immerzeel, J., Traag, W.A.

“…Within a survey on dioxins in animal fat used as feed ingredient, a sample originating from pigs offal was shown to contain 50 ng Toxic Equivalents (TEQ)…”
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Toxicokinetic model assessment on the dechlorination of dietary toxaphene CHB-62 into CHB-44 in Atlantic salmon (Salmo salar L.) by Berntssen, M.H.G, Lock, E.J, Zeilmaker, M.J, Van Eijkeren, J.C.H

“…European Union legislation on the upper limits of toxaphene in feed and food include the congeners CHB-26, CHB-62 and CHB-50 and is set at 50 µg kg⁻¹ feed for…”
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Toxicokinetics and carry-over model of α-hexabromocyclododecane (HBCD) from feed to consumption-sized Atlantic salmon (Salmo salar) by Berntssen, M.H.G, Valdersnes, S, Rosenlund, G, Torstensen, B.E, Zeilmaker, M.J, van Eijkeren, J.C.H

“…A two-compartmental model for the kinetics of carry-over of the brominated flame retardant α-hexabromocyclododecane (HBCD) from feed to the fillet of farmed…”
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S10-02 New Approach Methodologies (NAMs): a quantitative in vitro to in vivo extrapolation case study with perfluorinated compounds by Fragki, S., Paini, A., Iulini, M., Corsini, E., Bokkers, B., Luijten, M., Pijnenburg, A., Piersma, A.H., Zeilmaker, M.J., Rijkers, D., Siccardi, M., Schaller, S.

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The integration of in vitro chemical transplacental passage into a generic PBK model for pregnancy by Fragki, S., Hogeenveen, R., van Ooostrom, C., Schwillens, P., Piersma, A.H., Zeilmaker, M.J.

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In vitro to in vivo extrapolation of effective concentrations in alternative assays for developmental toxicity testing: Application of generic PBK modelling by Fragki, S., Piersma, A.H., Rorije, E., Zeilmaker, M.J.

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Study on the effects of 19 perfluoroalkyl substances on gene expression and biokinetics of PFOS and PFOA in human HepaRG liver cells by Fragki, S., Rijkers, D., Janssen, A., Staats, M., Zeilmaker, M.J., Piersma, A., Luijten, M., Hoogenboom, R., Peijnenburg, A., Louisse, J.

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Approaches to mixture risk assessment of PFASs in the European population based on human hazard and biomonitoring data by Bil, W., Govarts, E., Zeilmaker, M.J., Woutersen, M., Bessems, J., Ma, Y., Thomsen, C., Haug, L.S., Lignell, S., Gyllenhammar, I., Palkovicova Murinova, L., Fabelova, L., Tratnik, J. Snoj, Kosjek, T., Gabriel, C., Sarigiannis, D., Pedraza-Diaz, S., Esteban-López, M., Castaño, A., Rambaud, L., Riou, M., Franken, C., Colles, A., Vogel, N., Kolossa-Gehring, M., Halldorsson, T.I., Uhl, M., Schoeters, G., Santonen, T., Vinggaard, A.M.

“…Per- and polyfluoroalkyl substances (PFASs) are a highly persistent, mobile, and bioaccumulative class of chemicals, of which emissions into the environment…”
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Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and biphenyls (PCBs) in home-produced eggs by Hoogenboom, Ron L.A.P., ten Dam, Guillaume, van Bruggen, Mark, Jeurissen, Suzanne M.F., van Leeuwen, Stefan P.J., Theelen, Rob M.C., Zeilmaker, Marco J.

“…Home produced eggs from 62 addresses in the Netherlands were investigated for the levels of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs) and…”
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Carry-over of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) in dairy cows fed smoke contaminated maize silage or sugar beet pulp by Hoogenboom, Ron L.A.P., Klop, Arie, Herbes, Rik, van Eijkeren, Jan C.H., Zeilmaker, Marco J., van Vuuren, Ad M., Traag, Wim A.

“…•Cows were fed with maize silage or beet pulp contaminated with dioxins due to smoke.•Maize levels around the maximum level caused milk levels close to the…”
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Accumulation of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in livers of young sheep by Hoogenboom, Ron L A P, Stark, Marie Luise, Spolders, Markus, Zeilmaker, Marco J, Traag, Wim A, Ten Dam, Guillaume, Schafft, Helmut A

“…A major part of sheep livers contains levels of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) above the…”
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Modelling of the feed-to-fillet transfer of ethoxyquin and one of its main metabolites, ethoxyquin dimer, to the fillet of farmed Atlantic salmon (Salmon salar L.) by Berntssen, M.H.G., Hoogenveen, R., Bernhard, A., Lundebye, A.-K., Ørnsrud, R, Zeilmaker, M.J.

“…Ethoxyquin (EQ) is an antioxidant supplemented to feed ingredients, mainly fish meal, which is currently under re-evaluation for use in the food production…”
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Dioxins (polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo-furans) in traditional clay products used during pregnancy by Reeuwijk, Noortje M., Talidda, Antonia, Malisch, Rainer, Kotz, Alexander, Tritscher, Angelika, Fiedler, Heidelore, Zeilmaker, Marco J., Kooijman, Martin, Wienk, Koen J.H., Traag, Wim A., Hoogenboom, Ron L.A.P.

“…► We determined PCDD/F levels of clays taken orally during pregnancy. ► PCDD/F levels in some clays were high, up to 103ng TEQ kg−1. ► We compared congener…”
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Dietary intake and risk evaluation of polybrominated diphenyl ethers in The Netherlands by Bakker, Martine I., de Winter-Sorkina, Renata, de Mul, Anika, Boon, Polly E., van Donkersgoed, Gerda, van Klaveren, Jacob D., Baumann, Bert A., Hijman, Willie C., van Leeuwen, Stefan P. J., de Boer, Jacob, Zeilmaker, Marco J.

“…The current study aims at estimating the dietary intake of PBDEs in the Netherlands and evaluating the resultant risk. Dietary intake was estimated using…”
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Dietary exposure to dioxins and dioxin-like PCBs in The Netherlands anno 2004 by De Mul, Anika, Bakker, Martine I., Zeilmaker, Marco J., Traag, Wim A., Leeuwen, Stefan P.J. van, Hoogenboom, Ron L.A.P., Boon, Polly E., Klaveren, Jacob D. van

“…In this study, representative occurrence data for PCDD/Fs and dioxin-like PCBs in food were obtained and used to estimate dietary exposure of the Dutch…”
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Carryover of cadmium from feed in growing pigs by Hoogenboom, Ron L.A.P, Hattink, Jasper, van Polanen, Ab, van Oostrom, Sjaak, Verbunt, John T, Traag, Wim A, Kan, Kees A, van Eijkeren, Jan C.H, De Boeck, Gudrun, Zeilmaker, Marco J

“…Growing male pigs were exposed to cadmium (Cd) at levels around 1 and 10 mg kg –¹ feed for up to 12 weeks, administered as CdCl ₂ or Cd-cysteine (CdCys). Pigs…”
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Does EU legislation allow the use of the Benchmark dose (BMD) approach for risk assessment? by Brandon, E.F.A., Bulder, A.S., van Engelen, J.G.M., Mahieu, C.M., Mennes, W.C., Pronk, M.E.J., Rietveld, A.G., van de Ven, B.M., ten Voorde, S.E.C.G., Wolterink, G., Slob, W., Zeilmaker, M.J., Bessems, J.G.M.

“…•EFSA scientific opinion states Benchmark dose (BMD) approach is preferred.•EU regulatory frameworks for chemicals were scanned for obstacles.•EU legislation…”
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Carry-over of dioxins and PCBs from feed and soil to eggs at low contamination levels-- influence of mycotoxin binders on the carry-over from feed to eggs by Hoogenboom, L A P, Kan, C A, Zeilmaker, M J, Van Eijkeren, J, Traag, W A

“…Laying hens were fed with compound feed containing six different levels of dioxins, dioxin-like PCBs and indicator PCBs for a period of 56 days. This was…”
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