Search Results - "Zehnder, Tobias"

Predicting enhancers in mammalian genomes using supervised hidden Markov models by Zehnder, Tobias, Benner, Philipp, Vingron, Martin

“…Eukaryotic gene regulation is a complex process comprising the dynamic interaction of enhancers and promoters in order to activate gene expression. In recent…”
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Fabrication of Cell-Loaded Two-Phase 3D Constructs for Tissue Engineering by Zehnder, Tobias, Freund, Tim, Demir, Merve, Detsch, Rainer, Boccaccini, Aldo R

“…Hydrogel optimisation for biofabrication considering shape stability/mechanical properties and cell response is challenging. One approach to tackle this issue…”
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Evaluation of an alginate-gelatine crosslinked hydrogel for bioplotting by Zehnder, Tobias, Sarker, Bapi, Boccaccini, Aldo R, Detsch, Rainer

“…Using additive manufacturing to create hydrogel scaffolds which incorporate homogeneously distributed, immobilized cells in the context of biofabrication…”
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Biofabrication of a co-culture system in an osteoid-like hydrogel matrix by Zehnder, Tobias, Boccaccini, Aldo R, Detsch, Rainer

“…Biofabrication aims to develop functional, biological constructs using automated processes (additive manufacturing, AM) involving different cell types and…”
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Thinning the thickets: Foraging of hardy cattle, sheep and goats in green alder shrubs by Pauler, Caren M., Zehnder, Tobias, Staudinger, Markus, Lüscher, Andreas, Kreuzer, Michael, Berard, Joël, Schneider, Manuel K.

“…Green alder shrubs Alnus viridis increasingly overgrow European mountain pastures but hinder natural forest succession. This nitrogen‐fixing, autochthonous…”
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Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes by Ringel, Alessa R, Szabo, Quentin, Chiariello, Andrea M, Chudzik, Konrad, Schöpflin, Robert, Rothe, Patricia, Mattei, Alexandra L, Zehnder, Tobias, Harnett, Dermot, Laupert, Verena, Bianco, Simona, Hetzel, Sara, Glaser, Juliane, Phan, Mai H Q, Schindler, Magdalena, Ibrahim, Daniel M, Paliou, Christina, Esposito, Andrea, Prada-Medina, Cesar A, Haas, Stefan A, Giere, Peter, Vingron, Martin, Wittler, Lars, Meissner, Alexander, Nicodemi, Mario, Cavalli, Giacomo, Bantignies, Frédéric, Mundlos, Stefan, Robson, Michael I

“…Regulatory landscapes drive complex developmental gene expression, but it remains unclear how their integrity is maintained when incorporating novel genes and…”
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Computational Approaches for the Prediction of Gene Regulatory Elements and the Analysis of Their Evolutionary Conservation by Zehnder, Tobias

“…In the last several decades, the field of molecular biology has made substantial progress in deciphering the many facets of gene expression and regulation. The…”
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Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements by Baranasic, Damir, Hörtenhuber, Matthias, Balwierz, Piotr J., Zehnder, Tobias, Mukarram, Abdul Kadir, Nepal, Chirag, Várnai, Csilla, Hadzhiev, Yavor, Jimenez-Gonzalez, Ada, Li, Nan, Wragg, Joseph, D’Orazio, Fabio M., Relic, Dorde, Pachkov, Mikhail, Díaz, Noelia, Hernández-Rodríguez, Benjamín, Chen, Zelin, Stoiber, Marcus, Dong, Michaël, Stevens, Irene, Ross, Samuel E., Eagle, Anne, Martin, Ryan, Obasaju, Oluwapelumi, Rastegar, Sepand, McGarvey, Alison C., Kopp, Wolfgang, Chambers, Emily, Wang, Dennis, Kim, Hyejeong R., Acemel, Rafael D., Naranjo, Silvia, Łapiński, Maciej, Chong, Vanessa, Mathavan, Sinnakaruppan, Peers, Bernard, Sauka-Spengler, Tatjana, Vingron, Martin, Carninci, Piero, Ohler, Uwe, Lacadie, Scott Allen, Burgess, Shawn M., Winata, Cecilia, van Eeden, Freek, Vaquerizas, Juan M., Gómez-Skarmeta, José Luis, Onichtchouk, Daria, Brown, Ben James, Bogdanovic, Ozren, van Nimwegen, Erik, Westerfield, Monte, Wardle, Fiona C., Daub, Carsten O., Lenhard, Boris, Müller, Ferenc

“…Zebrafish, a popular organism for studying embryonic development and for modeling human diseases, has so far lacked a systematic functional annotation program…”
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Oxidized Alginate-Gelatin Hydrogel: A Favorable Matrix for Growth and Osteogenic Differentiation of Adipose-Derived Stem Cells in 3D by Sarker, Bapi, Zehnder, Tobias, Rath, Subha N, Horch, Raymund E, Kneser, Ulrich, Detsch, Rainer, Boccaccini, Aldo R

“…Alginate-based hydrogels are extensively used matrices for cell encapsulation, but they need to be modified to recapitulate chemical, microstructural, and…”
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Macromolecular interactions in alginate–gelatin hydrogels regulate the behavior of human fibroblasts by Sarker, Bapi, Singh, Raminder, Zehnder, Tobias, Forgber, Tim, Alexiou, Christoph, Cicha, Iwona, Detsch, Rainer, Boccaccini, Aldo R

“…Due to the presence of tripeptide arginine–glycine–aspartic acid, gelatin is considered a very promising additive material to improve the cytocompatibility of…”
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Advanced alginate-based hydrogels by Detsch, Rainer, Sarker, Bapi, Zehnder, Tobias, Frank, Gerhard, Boccaccini, Aldo R.

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Biofabrication of 3D Alginate-Based Hydrogel for Cancer Research: Comparison of Cell Spreading, Viability, and Adhesion Characteristics of Colorectal HCT116 Tumor Cells by Ivanovska, Jelena, Zehnder, Tobias, Lennert, Pablo, Sarker, Bapi, Boccaccini, Aldo R, Hartmann, Arndt, Schneider-Stock, Regine, Detsch, Rainer

“…Hydrogels are an important class of biomaterials as they could mimic the extracellular matrix (ECM). Among the naturally occurring biopolymers, alginate and…”
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Dominant shrub species are a strong predictor of plant species diversity along subalpine pasture-shrub transects by Zehnder, Tobias, Lüscher, Andreas, Ritzmann, Carmen, Pauler, Caren M., Berard, Joel, Kreuzer, Michael, Schneider, Manuel K.

“…Abandonment of pastures and successional shrub expansion are widespread in European mountain regions. Moderate shrub encroachment is perceived beneficial for…”
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Bioplotting of a bioactive alginate dialdehyde-gelatin composite hydrogel containing bioactive glass nanoparticles by Leite, Álvaro J, Sarker, Bapi, Zehnder, Tobias, Silva, Raquel, Mano, João F, Boccaccini, Aldo R

“…Alginate dialdehyde-gelatin (ADA-GEL) constructs incorporating bioactive glass nanoparticles (BGNPs) were produced by biofabrication to obtain a grid-like…”
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Alpine and lowland grazing differentially alter the reproductive tract redox milieu and amino acid composition in cattle by Chiumia, Daniel, Hankele, Anna-Katharina, Drews, Barbara, Zehnder, Tobias, Berard, Joel, Giesbertz, Pieter, Ulbrich, Susanne E., Giller, Katrin

“…An alpine environment is unique due to pasture biodiversity, with an abundant content of natural antioxidant polyphenols. The present study investigated the…”
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