Search Results - "Zefirova, O. N"

New 1,1-dibenzyl-3-(1-benzyl-1H-pyrazol-4-yl)-2-methylisothioureas: synthesis and evaluation of antioxidant activity by Proshin, A. N., Trofimova, T. P., Globa, A. A., Dubrovskaya, E. S., Zefirova, O. N., Zefirov, N. A., Tafeenko, V. A., Dutova, T. Ya, Ugrak, B. I., Serkov, I. V.

“…1,1-Dibenzyl-3-(1-benzyl-1 1 H -pyrazol-4-yl)-2-methylisothioureas containing structural elements both of known antioxidants and glutamate receptor modulators…”
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New podophyllotoxin and epipodophyllotoxin derivatives with substituted isoxazole fragments by Zefirov, N. A., Nurieva, E. V., Mamaeva, A. V., Vasilenko, D. A., Sadovnikov, K. S., Averina, E. B., Kolchanova, A. Yu, Milaeva, E. R., Zefirova, O. N.

“…A series of podophyllotoxin and epipodophyllotoxin esters with methylisoxazole fragments containing a halogen atom or a nitro group at position 4 of the…”
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New C(4)-esters of podophyllotoxin and epipodophyllotoxin with heterocyclic moieties by Elisseev, I. A., Nurieva, E. V., Zefirov, N. A., Kolchanova, A. Yu, Skvortsov, D. A., Milaeva, E. R., Zefirova, O. N.

“…Esters of podophyllotoxin and epipodophyllotoxin with 4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)butanoic and (4 R )- N -( tert…”
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Screening of a series of 3,5-disubstituted 1,2,4-thiadiazoles for selectivity of cytotoxic action to cancer cells by Proshin, A. N., Trofimova, T. P., Zefirova, O. N., Zhirkina, I. V., Skvortsov, D. A., Bachurin, S. O.

“…New 3,5-disubstituted-1,2,4-thiadiazoles were synthesized and together with a series of their analogs obtained earlier were tested for cytotoxic activity to…”
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Rimantadine derivatives with antiviral activity against flaviviruses and rimantadine-resistant strain of influenza A virus by Zefirov, N. A., Khvatov, E. V., Nurieva, E. V., Esaulkova, Ya. L., Volobueva, A. S., Zarubaev, V. V., Goryashchenko, A. S., Yatsenko, D. O., Uvarova, V. I., Osolodkin, D. I., Ishmukhametov, A. A., Zefirova, O. N.

“…Pyridine-containing amides of rimantadine (1-(1-adamantyl)ethylamine) were synthesized by the amidation of rimantadine hydrochloride by the corresponding acids…”
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Role of structural components of the 2-methoxyestradiol—chlorambucil conjugate in microtubule stabilization by Zefirov, N. A., Korotkova, P. D., Shevtsova, E. F., Shevtsov, P. N., Mamaeva, A. V., Milaeva, E. R., Zefirova, O. N.

“…The conjugate of 2-methoxyestradiol, a ligand for the cell protein tubulin, with two molecules of chlorambucil, known as a DNA-alkylating agent, is capable of…”
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Novel analogs of 5-hydroxymethyl-2-methoxyphenyl adamantane-1-acetate: synthesis, biotesting, and molecular modeling by Zefirov, N. A., Mamaeva, A. V., Krasnoperova, A. I., Evteeva, Yu. A., Milaeva, E. R., Kuznetsov, S. A., Zefirova, O. N.

“…A series of novel analogs of dual-targeted antimitotic agent 5-hydroxymethyl-2-methoxyphenyl adamantane-1-acetate was synthesized. These compounds maintained…”
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Vibrational Spectra and Stable Conformations of Methyl 6-Methoxy-2,3,4,9-Tetrahydro-1H-1,4-Ethanocarbazole-3-Carboxylate by Davydova, I. B., Senyavin, V. M., Zefirova, O. N., Kuramshina, G. M.

“…A study is performed of IR absorption and Raman spectra of methyl 6-methoxy-2,3,4,9-tetrahydro-1H-1,4-ethanocarbazole-3-carboxylate. Optimized structures and…”
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Novel 5-N,N-disubstituted-5-amino-3-(2-oxopropyl)-1,2,4-thiadiazoles: synthesis and study of neuroprotective and antiproliferative properties by Proshin, A. N., Trofimova, T. P., Zefirova, O. N., Petrova, L. N., Skvortsov, D. A., Bachurin, S. O.

“…A series of eight novel 5- N , N -disubstituted-5-amino-3-(2-oxopropyl)-1,2,4-thiadiazoles with diverse lipophilic groups was obtained by reaction of…”
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“Triple” mutual prodrug based on 2-methoxyestradiol: synthesis and biotesting in vitro by Lavrushkina, E. A., Shibilev, V. M., Zefirov, N. A., Shevtsova, E. F., Shevtsov, P. N., Kuznetsov, S. A., Zefirova, O. N.

“…Ester of the tubulin ligand, 2-methoxyestradiol, with two molecules of DNA alkylating agent chlorambucil was proposed as a “triple” mutual prodrug for blocking…”
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Vibrational Spectra and Stable Conformations of (1RS, 5RS, 6SR)-6-Methoxycarbonylamino-(5'-methoxyindolo[2,3-b])bicyclo[3.2.1]oct-2-en by Davydova, I. B., Senyavin, V. M., Zefirova, O. N., Kuramshina, G. M.

“…The IR and Raman spectra of (1RS,5RS,6SR)-6-methoxycarbonylamino-(5'-methoxyindolo[2,3-b])bicyclo[3.2.1]oct-2-ene are investigated. Optimized structures and…”
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Synthesis of steroid analogs of tubuloclustin, their cytotoxicity and effect on microtubules of A549 carcinoma cells by Nurieva, E. V., Zefirov, N. A., Mamaeva, A. V., Wobith, B., Kuznetsov, S. A., Zefirova, O. N.

“…Synthesis of analogs of tubuloclustin ( N -(7-adamant-2-yloxy-7-oxoheptanoyl)- N -deacetylcolchicine ( 1 )) with the colchicine fragment replaced with…”
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Synthesis, Antiproliferative Activity, and Effect on Carcinoma A549 Cell Microtubules of New Tubuloclustin Analogs by Zefirov, N. A., Evteeva, Yu. A., Fatkulin, A. R., Schulz, S., Kuznetsov, S. A., Zefirova, O. N.

“…Combretastatin analogs of the antitumor agent tubuloclustin { N -[7-(adamant-2-yloxy)-7-oxoheptanoyl]- N deacetylcolchicine} were prepared via esterification…”
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Adamantane acid esters with alkoxyaryl alcohols: Synthesis, antiproliferative activity, and influence on microtubule network of tumor cells by Zefirov, N. A., Nurieva, E. V., Pikulina, Yu. A., Ogon´kov, A. V., Wobith, B., Kuznetsov, S. A., Zefirova, O. N.

“…Adamantaneacetic and adamantanecarboxylic acid esters containing 3-hydroxy-4-methoxybenzyl, 3,4,5-trimethoxybenzyl, or 5-(hydroxymethyl)-2-methoxyphenyl groups…”
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Diels-alder reaction as a synthetic approach to bicyclo[3.3.1]nonane colchicine analogs by Nurieva, E. V, Semenova, I. S, Nuriev, V. N, Shishov, D. V, Baskin, I. I, Zefirova, O. N, Zefirov, N. S

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Molecular and crystal structure of indole derivatives fused with substituted bicyclo[3.3.1]nonane by Zefirova, O. N., Potekhin, K. A., Touchin, A. I., Averina, N. V., Baranova, T. Yu, Zyk, N. V., Zefirov, N. S.

“…Molecular structures of oxime 6-oxo-indolo[2,3-b]-bicyclo[3.3.1]non-2-en 1 and 6-oxo-(5-methoxy-indolo[2,3-b])-bicyclo[3.3.1]non-2-en 2 were determined by…”
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Synthetic Approaches to Physiologically Active Polycyclic Compounds: VI. Synthesis of 1-[(2R,3S)-N-Benzoyl-phenylisoseryloxy]-4,4-dimethyladamantane by Zefirova, O. N., Nurieva, E. V., Zyk, N. V.

“…A convenient procedure was proposed for the synthesis of 4,4-dimethyladamantan-1-ol from 2-adamantanone. Esterification of the product with protected amino…”
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Taxol: Synthesis, Bioactive Conformations, and Structure-Activity Relationships in Its Analogs by Zefirova, O. N., Nurieva, E. V., Ryzhov, A. N., Zyk, N. V., Zefirov, N. S.

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Aqueous solutions of poly-N-alkyl-substituted acrylamides: Structure and properties related to targeted transport by Valuev, L. I., Chupov, V. V., Zefirova, O. N., Lebedeva, T. L., Platé, N. A.

“…Abstract…”
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C(7)-Derivatives of colchicine with guanosine and biphenyl moieties: molecular modeling, synthesis, and tubulin clustering effect in cancer cells by Nurieva, E. V., Zefirov, N. A., Temnyakova, N. S., Kuznetsov, S. A., Zefirova, O. N.

“…Two novel C(7)-derivatives of natural anticancer agent colchicine were designed with the purpose to study their ability to induce tubulin clustering in cancer…”
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