Search Results - "Zefirov, Andrey L."

Early Alterations in Structural and Functional Properties in the Neuromuscular Junctions of Mutant FUS Mice by Mukhamedyarov, Marat A, Khabibrakhmanov, Aydar N, Khuzakhmetova, Venera F, Giniatullin, Arthur R, Zakirjanova, Guzalia F, Zhilyakov, Nikita V, Mukhutdinova, Kamilla A, Samigullin, Dmitry V, Grigoryev, Pavel N, Zakharov, Andrey V, Zefirov, Andrey L, Petrov, Alexey M

“…Amyotrophic lateral sclerosis (ALS) is manifested as skeletal muscle denervation, loss of motor neurons and finally severe respiratory failure. Mutations of…”
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Early Lipid Raft-Related Changes: Interplay between Unilateral Denervation and Hindlimb Suspension by Bryndina, Irina G, Shalagina, Maria N, Protopopov, Vladimir A, Sekunov, Alexey V, Zefirov, Andrey L, Zakirjanova, Guzalia F, Petrov, Alexey M

“…Muscle disuse and denervation leads to muscle atrophy, but underlying mechanisms can be different. Previously, we have found ceramide (Cer) accumulation and…”
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Changes in Membrane Ceramide Pools in Rat Soleus Muscle in Response to Short-Term Disuse by Petrov, Alexey M, Shalagina, Maria N, Protopopov, Vladimir A, Sergeev, Valeriy G, Ovechkin, Sergey V, Ovchinina, Natalia G, Sekunov, Alexey V, Zefirov, Andrey L, Zakirjanova, Guzalia F, Bryndina, Irina G

“…Lipid raft disruption is an early event during skeletal muscle unloading. Ceramide (Cer) serves as a signaling lipid that can contribute to lipid raft…”
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Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse by Kravtsova, Violetta V, Petrov, Alexey M, Matchkov, Vladimir V, Bouzinova, Elena V, Vasiliev, Alexander N, Benziane, Boubacar, Zefirov, Andrey L, Chibalin, Alexander V, Heiny, Judith A, Krivoi, Igor I

“…The Na,K-ATPase is essential for the contractile function of skeletal muscle, which expresses the α1 and α2 subunit isoforms of Na,K-ATPase. The α2 isozyme is…”
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Human APP Gene Expression Alters Active Zone Distribution and Spontaneous Neurotransmitter Release at the Drosophila Larval Neuromuscular Junction by Krivoi, Igor I., Bolshakova, Olga I., Zefirov, Andrey L., Ryabova, Elena V., Kravtsova, Violetta V., Vasiliev, Alexander N., Saburova, Ekaterina A., Sarantseva, Svetlana V.

“…This study provides further insight into the molecular mechanisms that control neurotransmitter release. Experiments were performed on larval neuromuscular…”
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Role of membrane cholesterol in spontaneous exocytosis at frog neuromuscular synapses: reactive oxygen species–calcium interplay by Petrov, Alexey M., Yakovleva, Anastasiya A., Zefirov, Andrey L.

“…Key points Cholesterol depletion increases reactive oxygen species (ROS) levels in extra‐ and intracellular space through NAPDH oxidase activation, which is…”
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Membrane lipid rafts are disturbed in the response of rat skeletal muscle to short-term disuse by Petrov, Alexey M, Kravtsova, Violetta V, Matchkov, Vladimir V, Vasiliev, Alexander N, Zefirov, Andrey L, Chibalin, Alexander V, Heiny, Judith A, Krivoi, Igor I

“…Marked loss of skeletal muscle mass occurs under various conditions of disuse, but the molecular and cellular mechanisms leading to atrophy are not completely…”
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Ovalbumin-induced sensitization affects non-quantal acetylcholine release from motor nerve terminals and alters contractility of skeletal muscles in mice by Teplov, Alexander Y., Grishin, Sergey N., Mukhamedyarov, Marat A., Ziganshin, Airat U., Zefirov, Andrey L., Palotás, András

“…Skeletal muscles play key roles in the development of various pathologies, including bronchial asthma and several types of auto-immune disorders, e.g…”
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State-of-the-Art Technologies for Studying Cellular and Molecular Mechanisms Underlying Alzheimer's Disease by Mukhamedyarov, Marat A., Akhmadieva, Liaisan A., Nagiev, Kerim K., Zefirov, Andrey L.

“…Alzheimer's disease (AD) is the most common neurodegenerative disease and cause of dementia. It is associated with progressive cognitive decline due to the…”
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Coronary artery bypass surgery provokes Alzheimer's disease-like changes in the cerebrospinal fluid by Palotás, András, Reis, Helton J, Bogáts, Gábor, Babik, Barna, Racsmány, Mihály, Engvau, Linda, Kecskeméti, Eva, Juhász, Anna, Vieira, Luciene B, Teixeira, Antônio L, Mukhamedyarovi, Marat A, Rizvanov, Albert A, Yalvaç, Mehmet E, Guimarães, Melissa M, Ferreira, Cláudia N, Zefirov, Andrey L, Kiyasov, Andrey P, Wang, Lan, Janka, Zoltán, Kálmán, János

“…Several biomarkers are used in confirming the diagnosis of cognitive disorders. This study evaluates whether the level of these markers after heart surgery…”
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Transcriptional Analysis of Blood Lymphocytes and Skin Fibroblasts, Keratinocytes, and Endothelial Cells as a Potential Biomarker for Alzheimer's Disease by Mukhamedyarov, Marat A, Rizvanov, Albert A, Yakupov, Eduard Z, Zefirov, Andrey L, Kiyasov, Andrey P, Reis, Helton J, Teixeira, Antônio L, Vieira, Luciene B, Lima, Luciana M, Salafutdinov, Ilnur I, Petukhova, Elena O, Khaiboullina, Svetlana F, Schlauch, Karen A, Lombardi, Vincent C, Palotás, András

“…Alzheimer's disease (AD) is a devastating and progressive form of dementia that is typically associated with a build-up of amyloid-β plaques and…”
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Improved cognitive, affective and anxiety measures in patients with chronic systemic disorders following structured physical activity by Teixeira, Robson Bonoto, Marins, João Carlos Bouzas, de Sá Junior, Antonio Reis, de Carvalho, Cristiane Junqueira, da Silva Moura, Tiago Augusto, Lade, Carlos Gabriel, Rizvanov, Albert A, Kiyasov, Andrey P, Mukhamedyarov, Marat A, Zefirov, Andrey L, Palotás, András, Lima, Luciana Moreira

“…Mental illnesses are frequent co-morbid conditions in chronic systemic diseases. High incidences of depression, anxiety and cognitive impairment complicate…”
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The mechanisms of multi-component paired-pulse facilitation of neurotransmitter release at the frog neuromuscular junction by Mukhamedyarov, Marat A., Grishin, Sergey N., Zefirov, Andrey L., Palotás, András

“…We have studied the mechanisms of paired-pulse facilitation (PPF) of neurotransmitter release in isolated nerve-muscle preparations of the frog cutaneous…”
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Extraneuronal toxicity of Alzheimer's β-amyloid peptide: Comparative study on vertebrate skeletal muscles by Mukhamedyarov, Marat A., Teplov, Alexander Y., Grishin, Sergey N., Leushina, Alina V., Zefirov, Andrey L., Palotás, András

“…Introduction. Alzheimer's β‐amyloid peptide (βAP) is known to possess a wide range of toxic effects on neurons in vitro and in vivo; however, there is little…”
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All-or-Nothing Type Biphasic Cytokine Production of Human Lymphocytes After Exposure to Alzheimer's β-Amyloid Peptide by Teixeira, Antônio L, Reis, Helton J, Coelho, Fernanda M, Carneiro, Daniel S, Teixeira, Mauro M, Vieira, Luciene B, Mukhamedyarov, Marat A, Zefirov, Andrey L, Janka, Zoltán, Palotás, András

“…Background Neuro-inflammation, triggered by β-amyloid peptide, is implicated as one of the primary contributors to Alzheimer's disease (AD) pathogenesis, and…”
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Alzheimer’s β-Amyloid-Induced Depolarization of Skeletal Muscle Fibers: Implications for Motor Dysfunctions in Dementia by Mukhamedyarov, Marat A., Grishin, Sergey N., Yusupova, Elvina R., Zefirov, Andrey L., Palotás, András

“…Numerous findings obtained over the last decades suggest that accumulation of β-amyloid peptide (βAP) plays the central role in the pathogenesis of Alzheimer’s…”
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The contribution of calcium/calmodulin-dependent protein-kinase II (CaMKII) to short-term plasticity at the neuromuscular junction by Mukhamedyarov, Marat A, Kochunova, Julia O, Yusupova, Elvina R, Haidarov, Bulat A, Zefirov, Andrey L, Palotás, András

“…Abstract Calcium/calmodulin-dependent protein-kinase II (CaMKII) is a ubiquitous intracellular enzyme, which is implicated in learning and memory mechanisms in…”
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Paired-pulse facilitation of transmitter release at different levels of extracellular calcium concentration by Mukhamedyarov, Marat A, Zefirov, Andrey L, Palotás, András

“…High-frequency synaptic activity can cause facilitation of transmitter release due to accumulation of "residual Ca(2+)" at the nerve terminal. However, the…”
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Modulation of neurotransmitter release by carbon monoxide at the frog neuro-muscular junction by Sitdikova, Guzel F, Islamov, Rustem R, Mukhamedyarov, Marat A, Permyakova, Vladlena V, Zefirov, Andrey L, Palotás, András

“…Carbon monoxide (CO) is an endogenous gaseous messenger, which regulates numerous physiological functions in a wide variety of tissues. Using extracellular…”
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Different effects of ATP on the contractile activity of mice diaphragmatic and skeletal muscles by Grishin, Sergey N., Teplov, Alexander Y., Galkin, Alexander V., Devyataev, Alexander M., Zefirov, Andrey L., Mukhamedyarov, Marat A., Ziganshin, Airat U., Burnstock, Geoffrey, Palotás, András

“…Apart from acetyl-choline (Ach), adenosine-5′-trisphosphate (ATP) is thought to play a role in neuromuscular function, however little information is available…”
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