Search Results - "Zee, Tiffany"

Comprehensive proteomic quantification of bladder stone progression in a cystinuric mouse model using data-independent acquisitions by Rose, Jacob, Basisty, Nathan, Zee, Tiffany, Wehrfritz, Cameron, Bose, Neelanjan, Desprez, Pierre-Yves, Kapahi, Pankaj, Stoller, Marshall, Schilling, Birgit

“…Cystinuria is one of various disorders that cause biomineralization in the urinary system, including bladder stone formation in humans. It is most prevalent in…”
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Inhibition of Leptin Regulation of Parasympathetic Signaling as a Cause of Extreme Body Weight-Associated Asthma by Arteaga-Solis, Emilio, Zee, Tiffany, Emala, Charles W., Vinson, Charles, Wess, Jürgen, Karsenty, Gerard

“…Impaired lung function caused by decreased airway diameter (bronchoconstriction) is frequently observed whether body weight is abnormally high or low. That…”
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A Drosophila model identifies a critical role for zinc in mineralization for kidney stone disease by Chi, Thomas, Kim, Man Su, Lang, Sven, Bose, Neelanjan, Kahn, Arnold, Flechner, Lawrence, Blaschko, Sarah D, Zee, Tiffany, Muteliefu, Gulinuer, Bond, Nichole, Kolipinski, Marysia, Fakra, Sirine C, Mandel, Neil, Miller, Joe, Ramanathan, Arvind, Killilea, David W, Brückner, Katja, Kapahi, Pankaj, Stoller, Marshall L

“…Ectopic calcification is a driving force for a variety of diseases, including kidney stones and atherosclerosis, but initiating factors remain largely unknown…”
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T-Cell Protein Tyrosine Phosphatase Regulates Bone Resorption and Whole-Body Insulin Sensitivity through Its Expression in Osteoblasts by Zee, Tiffany, Settembre, Carmine, Levine, Robert L., Karsenty, Gerard

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner by Zee, Tiffany, Boller, Sören, Györy, Ildiko, Makinistoglu, Munevver P., Tuckermann, Jan P., Grosschedl, Rudolf, Karsenty, Gerard

“…► The transcription factor Ebf1 is expressed at low levels in osteoblasts. ► Osteoblast-specific deletion of Ebf1 in the mouse does not result in a bone…”
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Mass Spectrometry-based in vitro Assay to Identify Drugs that Influence Cystine Solubility by Bose, Neelanjan, Zee, Tiffany, Kapahi, Pankaj, Stoller, Marshall L

“…Cystinuria is a rare genetic disorder characterized by recurrent, painful kidney stones, primarily composed of cystine, the dimer of the amino acid cysteine…”
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Abstract 4138847: Home Blood Pressure Reductions With Zilebesiran In Patients With Mild-To-Moderate Hypertension Are Consistent With Ambulatory And Office Blood Pressure Reductions In The KARDIA-1 Study by Zappe, Dion, Saxena, Manish, Desai, Akshay, Nweke, Chinedu, Basile, Jan, Carr, George, Chauhan, Rajvir, Zee, Tiffany, Goyal, Nitender, Bakris, George

“…Abstract only Background: Zilebesiran is an investigational subcutaneous (SC) RNA interference therapeutic targeting hepatic angiotensinogen synthesis. In the…”
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Abstract 116: Safety And Tolerability Of Zilebesiran, An RNA Interference Therapeutic Targeting Hepatic Angiotensinogen Synthesis, In Obese Patients With Hypertension by Taubel, Jorg, Desai, Akshay S, Lasko, Maxwell, Zee, Tiffany, Stiglitz, Daniel, Rhyee, Sean, Zappe, Dion H, Bakris, George L

“…Abstract only Introduction: Single subcutaneous (SC) doses of zilebesiran, an investigational RNA interference therapeutic targeting hepatic angiotensinogen…”
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KARDIA-3 STUDY DESIGN: ZILEBESIRAN AS ADD-ON THERAPY IN PATIENTS WITH HIGH CARDIOVASCULAR RISK AND HYPERTENSION INADEQUATELY CONTROLLED BY STANDARD OF CARE ANTIHYPERTENSIVES by Havasi, Andrea, Pagidipati, Neha, Bakris, George, Weber, Michael, Bengus, Monica, Daga, Shruti, Xiang, Zhihua, Zee, Tiffany, Bhan, Ishir, Granger, Christopher Bull

“…Objective: Zilebesiran is an investigational subcutaneous (SC) RNA interference therapeutic that targets synthesis of hepatic angiotensinogen, the most…”
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PTPN2 Regulates Metabolic Flux to Affect β-Cell Susceptibility to Inflammatory Stress by Kim, Yong Kyung, Kim, Youngjung Rachel, Wells, Kristen L, Sarbaugh, Dylan, Guney, Michelle, Tsai, Chia-Feng, Zee, Tiffany, Karsenty, Gerard, Nakayasu, Ernesto S, Sussel, Lori

“…Protein tyrosine phosphatase N2 (PTPN2) is a type 1 diabetes (T1D) candidate gene identified from human genome-wide association studies. PTPN2 is highly…”
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α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria by Zee, Tiffany, Bose, Neelanjan, Zee, Jarcy, Beck, Jennifer N, Yang, See, Parihar, Jaspreet, Yang, Min, Damodar, Sruthi, Hall, David, O'Leary, Monique N, Ramanathan, Arvind, Gerona, Roy R, Killilea, David W, Chi, Thomas, Tischfield, Jay, Sahota, Amrik, Kahn, Arnold, Stoller, Marshall L, Kapahi, Pankaj

“…Excess urinary cystine can lead to painful stone formation. There is no current effective treatment, but here Pankaj Kapahi, Marshall Stoller and colleagues…”
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MP34-06 INHIBITION OF NUCLEATION AND GROWTH OF CYSTINE CRYSTALS IN URINE by Chrzan, Daryl, Ramaswamy, Krishna, Killilea, David, Zee, Tiffany, Chi, Thomas, Kapahi, Pankaj, Kahn, Arnold, Stoller, Marshall

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MP12-12 ?-LIPOIC ACID SUPPRESSES CYSTINE STONE FORMATION IN A GENETIC MOUSE MODEL OF CYSTINURIA by Zee, Tiffany, Bose, Neelanjan, Zee, Jarcy, Beck, Jennifer, Yang, See, Parihar, Jaspreet, Yang, Min, Damodar, Sruthi, Hall, David, O'Leary, Monique, Ramanathan, Arvind, Gerona, Roy, Killilea, David, Chi, Thomas, Tischfield, Jay, Sahota, Amrik, Kahn, Arnold, Kapahi, Pankaj, Stoller, Marshall

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MP33-04 HETEROGENEOUS NUCLEATION DRIVES THE FORMATION OF NON-CALCIUM URINARY STONES IN HUMANS AND DROSOPHILA MELANOGASTER by Chi, Thomas, Tasian, Gregory, Zee, Tiffany, Lang, Sven, Muteliefu, Gulinuer, Killilea, David, Kahn, Arnold, Kapahi, Pankaj, Stoller, Marshall

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Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria by Zee, Tiffany, Bose, Neelanjan, Zee, Jarcy, Beck, Jennifer N, Yang, See, Parihar, Jaspreet, Yang, Min, Damodar, Sruthi, Hall, David, O'Leary, Monique N, Ramanathan, Arvind, Gerona, Roy R, Killilea, David W, Chi, Thomas, Tischfield, Jay, Sahota, Amrik, Kahn, Arnold, Stoller, Marshall L, Kapahi, Pankaj

“…Cystinuria is an incompletely dominant disorder characterized by defective urinary cystine reabsorption that results in the formation of cystine-based urinary…”
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Inhibition of Leptin Regulation of Parasympathetic Signaling as a Cause of Extreme Body Weight-Associated Asthma by Arteaga-Solis, Emilio, Zee, Tiffany, Emala, Charles W., Vinson, Charles, Wess, Jürgen, Karsenty, Gerard

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Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population by Coffee, Erin M, Yerkes, Laura, Ewen, Elizabeth P, Zee, Tiffany, Tolan, Dean R

“…Mutations in the aldolase B gene (ALDOB) impairing enzyme activity toward fructose-1-phosphate cleavage cause hereditary fructose intolerance (HFI). Diagnosis…”
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Non-autonomous regulation of bone mass accrual and the role of T-cell protein tyrosine phosphatase in the bone regulation of insulin sensitivity by Zee, Tiffany

“…The skeleton is a highly dynamic organ that undergoes constant remodeling to renew itself and maintain bone mass. It is subject to regulation from both…”
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MP33-04 HETEROGENEOUS NUCLEATION DRIVES THE FORMATION OF NON-CALCIUM URINARY STONES IN HUMANS AND DROSOPHILA MELANOGASTER by Chi, Thomas, Tasian, Gregory, Zee, Tiffany, Lang, Sven, Muteliefu, Gulinuer, Killilea, David, Kahn, Arnold, Kapahi, Pankaj, Stoller, Marshall

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A Drosophila Model Identifies a Critical Role for Zinc in Mineralization for Kidney Stone Disease: e0124150 by Chi, Thomas, Kim, Man Su, Lang, Sven, Bose, Neelanjan, Kahn, Arnold, Flechner, Lawrence, Blaschko, Sarah D, Zee, Tiffany, Muteliefu, Gulinuer, Bond, Nichole

“…Ectopic calcification is a driving force for a variety of diseases, including kidney stones and atherosclerosis, but initiating factors remain largely unknown…”
Get full text