Search Results - "Zecharyahu, Lital"
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Loss of heterochromatin and retrotransposon silencing as determinants in oocyte aging
Published in Aging cell (01-03-2022)“…Mammalian oocyte quality reduces with age. We show that prior to the occurrence of significant aneuploidy (9M in mouse), heterochromatin histone marks are…”
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Pre-pubertal oocytes harbor altered histone modifications and chromatin configuration
Published in Frontiers in cell and developmental biology (10-01-2023)“…Pre-pubertal oocytes are still dormant. They are arrested in a GV state and do not undergo meiotic divisions naturally. A multitude of molecular pathways are…”
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068 - EXAMINING THE ROLE OF SIRT1 CLEAVAGE ON AGE-DEPENDENT OA PROGRESSION FOR MALE MICE
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
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EXAMINING THE ROLE OF SIRT1 CLEAVAGE ON AGE-DEPENDENT OA PROGRESSION FOR MALE MICE
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
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Lef1 ablation alleviates cartilage mineralization following posttraumatic osteoarthritis induction
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2022)“…SignificanceCartilage mineralization is imperative in various processes such as skeletal growth and fracture repair. However, this process may also be…”
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HU308 Mitigates Osteoarthritis by Stimulating Sox9‐Related Networks of Carbohydrate Metabolism
Published in Journal of bone and mineral research (01-01-2023)“…ABSTRACT Osteoarthritis (OA) is characterized by progressive, irreversible erosion of articular cartilage accompanied by severe pain and immobility. This study…”
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