Search Results - "Zbinden, A. M."

Different benefit of bispectal index (BIS™) in desflurane and propofol anesthesia by Luginbühl, M., Wüthrich, S., Petersen-Felix, S., Zbinden, A. M., Schnider, T. W.

“…Background: Bispectal index (BIS™) monitoring may reduce drug usage and hasten recovery in propofol and inhalation anesthesia. The faster emergence profile of…”
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The Effect of N-Methyl-D-aspartate Antagonist (Ketamine) on Single and Repeated Nociceptive Stimuli: A Placebo-Controlled Experimental Human Study by Arendt-Nielsen, L., Petersen-Felix, S., Fischer, M., Bak, P., Bjerring, P., Zbinden, A. M.

“…Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor channel blocker known to inhibit "wind-up" and hence central hyperexcitability of dorsal horn…”
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Effect of racemic mixture and the (S+)-isomer of ketamine on temporal and spatial summation of pain by Arendt-Nielsen, L, Nielsen, J, Petersen-Felix, S, Schnider, T W, Zbinden, A M

“…We have compared the analgesic efficacy of the racemic mixture and the stereoisomer (S+) of the NMDA antagonist ketamine. In a double-blind, three-way…”
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Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. I: Motor reactions by ZBINDEN, A. M, MAGGIORINI, M, PETERSEN-FELIX, S, LAUBER, R, THOMSON, D. A, MINDER, C. E

“…Potency of inhaled anesthetics usually is defined by determining the minimal alveolar concentration (MAC) that prevents movement in 50% of patients in response…”
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Comparison of the analgesic potency of xenon and nitrous oxide in humans evaluated by experimental pain by Petersen-Felix, S, Luginbühl, M, Schnider, T W, Curatolo, M, Arendt-Nielsen, L, Zbinden, A M

“…We have compared the analgesic potency of MAC-equivalent concentrations of xenon (10, 20, 30 and 40%) and nitrous oxide (15, 30, 45 and 60%) in humans using a…”
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Model‐based control of mechanical ventilation: design and clinical validation by Martinoni, E.P., Pfister, Ch. A., Stadler, K.S., Schumacher, P.M., Leibundgut, D., Bouillon, T., Böhlen, T., Zbinden, A.M.

“…We developed a model‐based control system using end‐tidal carbon dioxide fraction (FE′CO2) to adjust a ventilator during clinical anaesthesia. We studied 16…”
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Anesthetic depth defined using multiple noxious stimuli during isoflurane/oxygen anesthesia. II: Hemodynamic responses by ZBINDEN, A. M, PETERSEN-FELIX, S, THOMSON, D. A

“…The hemodynamic effects of isoflurane have been studied extensively. However, most data are obtained from volunteers or patients in the absence of surgical…”
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Psychophysical and electrophysiological responses to experimental pain may be influenced by sedation: comparison of the effects of a hypnotic (propofol) and an analgesic (alfentanil) by Petersen-Felix, S, Arendt-Nielsen, L, Bak, P, Fischer, M, Zbinden, A M

“…Sedation may influence the responses of some experimental pain models used to test analgesic efficacy. In this study we compared the effects of a sedative…”
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Fuzzy logic control of mechanical ventilation during anaesthesia by Schäublin, J, Derighetti, M, Feigenwinter, P, Petersen-Felix, S, Zbinden, A M

“…We have examined a new approach, using fuzzy logic, to the closed-loop feedback control of mechanical ventilation during general anaesthesia. This control…”
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Model-based automatic feedback control versus human control of end-tidal isoflurane concentration using low-flow anaesthesia by Sieber, T.J., Frei, C.W., Derighetti, M., Feigenwinter, P., Leibundgut, D., Zbinden, A.M.

“…We studied the clinical use of an automatic feedback control system to adjust the end-tidal anaesthetic concentration with a low-flow method. The end-tidal…”
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Analgesic effect in humans of subanaesthetic isoflurane concentrations evaluated by experimentally induced pain by Petersen-Felix, S, Arendt-Nielsen, L, Bak, P, Roth, D, Fischer, M, Bjerring, P, Zbinden, A M

“…The analgesic effect of subanaesthetic concentrations of ether, trichloroethylene, methoxyflurane and halothane has been investigated previously using either…”
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Epidural Epinephrine and clonidine : Segmental analgesia and effects on different pain modalities by CURATOLO, M, PETERSEN-FELIX, S, ARENDT-NIELSEN, L, ZBINDEN, A. M

“…It is not known whether epidural epinephrine has an analgesic effect per se. The segmental distribution of clonidine epidural analgesia and its effects on…”
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Epidural fentanyl, adrenaline and clonidine as adjuvants to local anaesthetics for surgical analgesia: meta-analyses of analgesia and side-effects by Curatolo, M., Petersen-Felix, S., Scaramozzino, P., Zbinden, A. M.

“…Background: The risk/benefit ratio of adding fentanyl, adrenaline and clonidine to epidural local anaesthetics for improving intraoperative analgesia is…”
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A direct search procedure to optimize combinations of epidural bupivacaine, fentanyl, and clonidine for postoperative analgesia by CURATOLO, M, SCHNIDER, T. W, PETERSEN-FELIX, S, WEISS, S, SIGNER, C, SCARAMOZZINO, P, ZBINDEN, A. M

“…The authors applied an optimization model (direct search) to find the optimal combination of bupivacaine dose, fentanyl dose, clonidine dose, and infusion rate…”
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Arterial pressure control with isoflurane using fuzzy logic by Zbinden, A M, Feigenwinter, P, Petersen-Felix, S, Hacisalihzade, S

“…Arterial pressure is still one of the most important measures in estimating the required dose of inhaled anaesthetics. It is measured easily and reacts rapidly…”
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Temporal summation during extradural anaesthesia by Curatolo, M, Petersen-Felix, S, Arendt-Nielsen, L, Fischer, M, Zbinden, A M

“…We have investigated in 10 patients the effect of extradural anaesthesia on temporal summation by comparing pain thresholds to single and repeated (five…”
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Spinal anaesthesia inhibits central temporal summation by Curatolo, M, Petersen-Felix, S, Arendt-Nielsen, L, Zbinden, A M

“…In a previous investigation we found that extradural anaesthesia did not adequately inhibit temporal summation of repeated electrical stimuli: pain to repeated…”
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Isoflurane minimum alveolar concentration decreases during anesthesia and surgery by PETERSEN-FELIX, S, ZBINDEN, A. M, FISCHER, M, THOMSON, D. A

“…It generally is assumed that the potency of inhalational anesthetics remains unchanged during the course of the administration of an anesthetic. Only one study…”
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A multifactorial analysis to explain inadequate surgical analgesia after extradural block by Curatolo, M, Orlando, A, Zbinden, A M, Scaramozzino, P, Venuti, F S

“…A multivariate analysis of inadequate extradural analgesia was carried out prospectively on 1051 patients undergoing lumbar extradural anaesthesia for surgery…”
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Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia by Curatolo, M, Derighetti, M, Petersen-Felix, S, Feigenwinter, P, Fischer, M, Zbinden, A M

“…In order to evaluate the performance of feedback fuzzy logic control of inspired oxygen and isoflurane concentrations, we studied 30 patients undergoing…”
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