Search Results - "Zawilska, Jolanta B"

An Expanding World of Novel Psychoactive Substances: Opioids by Zawilska, Jolanta B

“…The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been…”
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NBOMes-Highly Potent and Toxic Alternatives of LSD by Zawilska, Jolanta B, Kacela, Monika, Adamowicz, Piotr

“…Recently, a new class of psychedelic compounds named NBOMe (or 25X-NBOMe) has appeared on the illegal drug market. NBOMes are analogs of the 2C family of…”
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Spice/K2 drugs – more than innocent substitutes for marijuana by Zawilska, Jolanta B., Wojcieszak, Jakub

“…Smokeable herbal mixtures containing synthetic agonists of cannabinoid receptors, known under brand names such as Spice, K2 and Kronic, represent a relatively…”
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Physiology and pharmacology of melatonin in relation to biological rhythms by Zawilska, Jolanta B., Skene, Debra J., Arendt, Josephine

“…Melatonin is an evolutionarily conserved molecule that serves a time-keeping function in various species. In vertebrates, melatonin is produced predominantly…”
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PACAP38 and PACAP6-38 Exert Cytotoxic Activity Against Human Retinoblastoma Y79 Cells by Wojcieszak, Jakub, Zawilska, Jolanta B.

“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a multifunctional neuropeptide expression of which has been found in various tumors of the brain…”
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Psychiatric and neurological complications of long COVID by Zawilska, Jolanta B., Kuczyńska, Katarzyna

“…COVID-19 was primarily considered a pulmonary disease with extrapulmonary manifestations. As the pandemic spread, there has been growing evidence that the…”
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Next generation of novel psychoactive substances on the horizon – A complex problem to face by Zawilska, Jolanta B, Andrzejczak, Dariusz

“…Highlights • In Europe 255 novel psychoactive substances (NPS) have been detected in 2012–2014. • Synthetic cannabimimetics and synthetic cathinones make up…”
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An expanding world of new psychoactive substances—designer benzodiazepines by Zawilska, Jolanta B., Wojcieszak, Jakub

“…•Designer benzodiazepines (DBZD) have recently emerged as recreational drugs.•Vast majority of DBZD are not registered as medications and have not undergone…”
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Designer cathinones—An emerging class of novel recreational drugs by Zawilska, Jolanta B, Wojcieszak, Jakub

“…Abstract A new group of recreational drugs, popularly known as “bath salts”, “plant feeders” or “plant food”, has recently emerged in numerous countries…”
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Orexin A Suppresses the Growth of Rat C6 Glioma Cells via a Caspase-Dependent Mechanism by Biegańska, Kaja, Sokołowska, Paulina, Jöhren, Olaf, Zawilska, Jolanta B.

“…Orexin A and orexin B (also known as hypocretins) are closely related peptides synthesized by hypothalamic neurons. They orchestrate diverse central and…”
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Methoxetamine – a novel recreational drug with potent hallucinogenic properties by Zawilska, Jolanta B.

“…•Methoxetamine (MXE), a structural analogue of ketamine, is a novel designer drug.•MXE is recreationally used due to its potent hallucinogenic and dissociate…”
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Abuse of fentanyl: An emerging problem to face by Kuczyńska, Katarzyna, Grzonkowski, Piotr, Kacprzak, Łukasz, Zawilska, Jolanta B.

“…•Fentanyl-related morbility and mortality has alarmingly increased in recent years.•Most fentanyl abuse involves illicitly produced drug mixed up with…”
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Role of Chemokines in the Development and Progression of Alzheimer’s Disease by Wojcieszak, Jakub, Kuczyńska, Katarzyna, Zawilska, Jolanta B.

“…Alzheimer’s disease (AD) is a progressive neurogenerative disorder manifested by gradual memory loss and cognitive decline due to profound damage of…”
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"Legal Highs"--An Emerging Epidemic of Novel Psychoactive Substances by Zawilska, Jolanta B

“…During the last decade, there has been an increase in the availability and use of novel psychoactive substances (NPS), also known as "legal highs," across the…”
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Non-fentanyl new synthetic opioids – An update by Zawilska, Jolanta B., Adamowicz, Piotr, Kurpeta, Marta, Wojcieszak, Jakub

“…New synthetic opioids (NSO) constitute one of the fastest-growing group of New Psychoactive Substances, which emerged on the illicit drug marker in the second…”
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Prodrugs: A challenge for the drug development by Zawilska, Jolanta B., Wojcieszak, Jakub, Olejniczak, Agnieszka B.

“…It is estimated that about 10% of the drugs approved worldwide can be classified as prodrugs. Prodrugs, which have no or poor biological activity, are…”
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Carfentanil – from an animal anesthetic to a deadly illicit drug by Zawilska, Jolanta B., Kuczyńska, Katarzyna, Kosmal, Wiktoria, Markiewicz, Katarzyna, Adamowicz, Piotr

“…•Carfentanil has contributed to an increase in opioids-related intoxications in recent years.•It is often detected in heroin, other street drugs and…”
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α-Pyrrolidinophenones: a new wave of designer cathinones by Zawilska, Jolanta B., Wojcieszak, Jakub

“…Recent years have witnessed a rapid increase in the number and prevalence of novel psychoactive substances (NPSs). Among them, pyrovalerone derivatives,…”
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Four Synthetic Cathinones: 3-Chloromethcathinone, 4-Chloromethcathinone, 4-Fluoro-α-Pyrrolidinopentiophenone, and 4-Methoxy-α-Pyrrolidinopentiophenone Produce Changes in the Spontaneous Locomotor Activity and Motor Performance in Mice with Varied Profiles by Wojcieszak, Jakub, Kuczyńska, Katarzyna, Zawilska, Jolanta B.

“…Two chloromethcathinones, 3-chloromethcathinone (3-CMC) and 4-chloromethcathinone (4-CMC), and two para -substituted α-pyrrolidinophenones,…”
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Mephedrone and other cathinones by Zawilska, Jolanta B

“…PURPOSE OF REVIEWNew designer drugs are constantly emerging in the illicit drug market and represent a significant health problem. A very popular class…”
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