Search Results - "Zavolan, M"
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Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression
Published in Briefings in functional genomics (01-12-2010)“…Eukaryotic cells express a large variety of ribonucleic acid-(RNA)-binding proteins (RBPs) with diverse affinity and specificity towards target RNAs that play…”
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MirZ: an integrated microRNA expression atlas and target prediction resource
Published in Nucleic acids research (01-07-2009)“…MicroRNAs (miRNAs) are short RNAs that act as guides for the degradation and translational repression of protein-coding mRNAs. A large body of work showed that…”
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Analysis of the Genetic Variability of Virulence-Related Loci in Epidemic Clones of Methicillin-Resistant Staphylococcus aureus
Published in Antimicrobial Agents and Chemotherapy (01-01-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Computational Analysis of Full-length cDNAs Reveals Frequent Coupling Between Transcriptional and Splicing Programs
Published in DNA research (01-04-2008)“…High-throughput sequencing studies revealed that the majority of human and mouse multi-exon genes have multiple splice forms. High-density oligonucleotide…”
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Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation
Published in Genome research (01-04-2013)“…Most of what is presently known about how miRNAs regulate gene expression comes from studies that characterized the regulatory effect of miRNA binding sites…”
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CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins
Published in Nucleic acids research (01-01-2011)“…The stability, localization and translation rate of mRNAs are regulated by a multitude of RNA-binding proteins (RBPs) that find their targets directly or with…”
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Virus-encoded microRNAs: novel regulators of gene expression
Published in Trends in microbiology (Regular ed.) (01-04-2006)“…MicroRNAs (miRNAs) are a class of small RNAs that have recently been recognized as major regulators of gene expression. They influence diverse cellular…”
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Cell-Type-Specific Signatures of MicroRNAs on Target mRNA Expression
Published in Proceedings of the National Academy of Sciences - PNAS (21-02-2006)“…Although it is known that the human genome contains hundreds of microRNA (miRNA) genes and that each miRNA can regulate a large number of mRNA targets, the…”
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Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis
Published in Nature communications (11-12-2020)“…Mutations in the RNA-binding protein Fused in Sarcoma (FUS) cause early-onset amyotrophic lateral sclerosis (ALS). However, a detailed understanding of central…”
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A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
Published in Cell (29-06-2007)“…MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or translation of fully or partially sequence-complementary target mRNAs. In…”
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A novel class of small RNAs bind to MILI protein in mouse testes
Published in Nature (13-07-2006)“…Small RNAs bound to Argonaute proteins recognize partially or fully complementary nucleic acid targets in diverse gene-silencing processes. A subgroup of the…”
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The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line
Published in Nature genetics (01-05-2009)“…The FANTOM4 study identified transcriptional start sites active during proliferation arrest and differentiation of the human monocytic cell line THP-1…”
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Identification of Virus-Encoded MicroRNAs
Published in Science (American Association for the Advancement of Science) (30-04-2004)“…RNA silencing processes are guided by small RNAs that are derived from double-stranded RNA. To probe for function of RNA silencing during infection of human…”
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The Small RNA Profile during Drosophila melanogaster Development
Published in Developmental cell (01-08-2003)“…Small RNAs ranging in size between 20 and 30 nucleotides are involved in different types of regulation of gene expression including mRNA degradation,…”
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Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype
Published in The American journal of pathology (01-09-2008)“…Alterations in microRNA (miRNA) expression in both human and animal models have been linked to many forms of cancer. Such miRNAs, which act directly as…”
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Identification of microRNAs of the herpesvirus family
Published in Nature methods (01-04-2005)“…Epstein-Barr virus (EBV or HHV4), a member of the human herpesvirus (HHV) family, has recently been shown to encode microRNAs (miRNAs). In contrast to most…”
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Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes
Published in Genome research (01-08-2003)“…Although mRNA decay rates are a key determinant of the steady-state concentration for any given mRNA species, relatively little is known, on a population…”
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Modeling the binding specificity of the RNA-binding protein GLD-1 suggests a function of coding region-located sites in translational repression
Published in RNA (Cambridge) (01-10-2013)“…To understand the function of the hundreds of RNA-binding proteins (RBPs) that are encoded in animal genomes it is important to identify their target RNAs…”
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Published in Nature (London) (05-12-2002)“…Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify…”
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