Search Results - "Zavodnik, I B"

Functional activity and morphology of isolated rat cardiac mitochondria under calcium overload. Effect of naringin by Kavalenia, T. A., Lapshina, E. A., Ilyich, T. V., Zhao, Hu-Cheng, Zavodnik, I. B.

“…The function of mitochondria as a regulator of myocyte calcium homeostasis has been extensively discussed. The aim of the present work was further…”
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Rat liver mitochondrial damage under acute or chronic carbon tetrachloride-induced intoxication: Protection by melatonin and cranberry flavonoids by Cheshchevik, V.T., Lapshina, E.A., Dremza, I.K., Zabrodskaya, S.V., Reiter, R.J., Prokopchik, N.I., Zavodnik, I.B.

“…In current societies, the risk of toxic liver damage has markedly increased. The aim of the present work was to carry out further research into the…”
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Redox regulation of mitochondrial functional activity by quinones by Krylova, N G, Kulahava, T A, Cheschevik, V T, Dremza, I K, Semenkova, G N, Zavodnik, I B

“…Quinones are among the rare compounds successfully used as therapeutic agents to correct mitochondrial diseases and as specific regulators of mitochondrial…”
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Study of the Interaction of Naringenin, Apigenin, and Menadione with Membranes using Fluorescent Probes and Quantum Chemistry by Veiko, A. G., Lapshina, E. A., Yukhnevich, H. G., Zavodnik, I. B.

“…Quantum-chemical modeling of the optimal geometries of naringenin, apigenin, and menadione was performed. Their electronic properties and interactions with…”
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Mitochondrial dysfunction and compensatory mechanisms in liver cells during acute carbon tetrachloride-induced rat intoxication by Zavodnik, I B

“…Electron-transport chain and redox-balance of mitochondria are important targets that are damaged during intoxication. The aim of the present work was to…”
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Membrane effects of nitrite-induced oxidation of human red blood cells by Zavodnik, I.B., Lapshina, E.A., Rekawiecka, K., Zavodnik, L.B., Bartosz, G., Bryszewska, M.

“…The aim of our investigation was to study the red blood cell (RBC) membrane effects of NaNO 2-induced oxidative stress. Hyperpolarization of erythrocyte…”
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Protective effects of melatonin against carbon tetrachloride hepatotoxicity in rats by Zavodnik, L. B., Zavodnik, I. B., Lapshina, E. A., Belonovskaya, E. B., Martinchik, D. I., Kravchuk, R. I., Bryszewska, M., Reiter, R. J.

“…Melatonin is an indolamine, mainly secreted by the pineal gland into the blood of mammalian species. The potential for protective effects of melatonin on…”
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Oxidative processes induced by tert-butyl hydroperoxide in human red blood cells: chemiluminescence studies by Domanski, A V, Lapshina, E A, Zavodnik, I B

“…The erythrocyte is a good model for investigation of the mechanisms of cell damage induced by oxidizing agents. Oxidative damage to cell components and…”
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Melatonin and succinate reduce rat liver mitochondrial dysfunction in diabetes by Zavodnik, I B, Lapshina, E A, Cheshchevik, V T, Dremza, I K, Kujawa, J, Zabrodskaya, S V, Reiter, R J

“…Mitochondrial dysfunction and an increase in mitochondrial reactive oxygen species in response to hyperglycemia during diabetes lead to pathological…”
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Diabetes mellitus: Metabolic effects and oxidative stress by Zavodnik, I. B., Dremza, I. K., Lapshina, E. A., Cheshchevik, V. T.

“…Diabetes mellitus is a complex polygenic pathology, which is characterized by numerous metabolic disorders. Progressive hyperglycemia developing during this…”
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Melatonin directly scavenges free radicals generated in red blood cells and a cell-free system: Chemiluminescence measurements and theoretical calculations by Zavodnik, I.B., Domanski, A.V., Lapshina, E.A., Bryszewska, M., Reiter, R.J.

“…Melatonin, a pineal secretory product, has properties of both direct and indirect powerful antioxidant. The aim of the present study was to compare the…”
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Complexations of β-cyclodextrins with naringenin, naringin and catechin: thermodynamic parameters and regulation of mitochondrial functions in vitro by Kovalenya, T.A., Ilyich, T.V., Lapshina, E.A., Stępniak, A., Palecz, B., Zavodnik, I.B.

“…Flavonoids are exogenous phytochemicals with high antioxidative potential. The present work provides the mechanism of the complexations of low water-soluble…”
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Hepatotoxic effects of acetaminophen. Protective properties of tryptophan derivatives by Dremza, I. K., Cheshchevik, V. T., Zabrodskaya, S. V., Maksimchik, Yu. Z., Sudnikovich, E. Yu, Lapshina, E. A., Zavodnik, I. B.

“…Rat intoxication with acetaminophen (APAP) (500–1500 mg/kg body weight, intragastrically) caused a considerable dose-dependent decrease in reduced glutathione…”
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Human red blood cell membrane potential and fluidity in glucose solutions by Zavodnik, I. B., Piasecka, A., Szosland, K., Bryszewska, M.

“…This study aimed to investigate the membrane potential and fluidity changes of human red blood cells subjected to isotonic glucose solutions. For the control…”
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Calorimetric and spectroscopic characterization of complexes between β-cyclodextrin or heptakis (2,6-di-O-methyl)-β-cyclodextrin and sertraline hydrochloride in aqueous solution by Belica, S., Jeziorska, D., Urbaniak, P., Buko, V.U., Zavodnik, I.B., Pałecz, B.

“…•SRT interacts stronger with DM-βCD than with βCD.•The aromatic parts of SRT are included inside cavities of examined cyclodextrins.•Equilibrium of inclusion…”
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Antioxidative enzyme and glutathione S-transferase activities in diabetic rats exposed to long-term ASA treatment by Lapshina, E.A., Sudnikovich, E.Ju, Maksimchik, Ju.Z., Zabrodskaya, S.V., Zavodnik, L.B., Kubyshin, V.L., Nocun, M., Kazmierczak, P., Dobaczewski, M., Watala, C., Zavodnik, I.B.

“…Low-dose acetylsalicylic acid (ASA) treatment is a standard therapeutic approach in diabetes mellitus for prevention of long-term vascular complications. The…”
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Protective effects of N-acetyl-L-cysteine against acute carbon tetrachloride hepatotoxicity in rats by Maksimchik, Yu. Z., Lapshina, E. A., Sudnikovich, E. Yu, Zabrodskaya, S. V., Zavodnik, I. B.

“…In recent years, N‐acetyl‐L‐cysteine (NAC) has been widely investigated as a potentially useful protective and antioxidative agent to be applied in many…”
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High-affinity choline uptake under various pH conditions: investigation of synaptosomal fluorescence by Chumakova, O. V., Zavodnik, I. B.

“…The choline transport into synaptosomes obtained from the rat brain striatum was studied in the presence and absence of Na+ ions within the pH range 3.9-9.1…”
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Hypochlorous acid-induced lysis of human erythrocytes. Inhibition of cellular damage by the isoflavonoid genistein-8-C-glucoside by Zavodnik, L B, Zavodnik, I B, Lapshina, E A, Shkodich, A P, Bryszewska, M, Buko, V U

“…Erythrocyte damage induced by hypochlorous acid (HOCl) results in cell lysis developing with time after the oxidant is removed (post-hemolysis). The apparent…”
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The effects of palmitate on human erythrocyte membrane potential and osmotic stability by Zavodnik, I B, Lapshina, E A, Palecz, D, Bryszewska, M

“…To evaluate the mechanism(s) of erythrocyte stabilization in hypotonic medium by free fatty acids, we have studied the effect of palmitic acid and its…”
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