Search Results - "Zaveri, Hitten P"

The roles of surgery and technology in understanding focal epilepsy and its comorbidities by Spencer, Dennis D, Gerrard, Jason L, Zaveri, Hitten P

“…Intracranial electrophysiological recording in patients with refractory focal epilepsy is the gold standard for defining epileptogenic tissue. Although the…”
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Slowing less than 1 Hz is decreased near the seizure onset zone by Lundstrom, Brian Nils, Boly, Melanie, Duckrow, Robert, Zaveri, Hitten P., Blumenfeld, Hal

“…Focal slowing (<4 Hz) of brain waves is often associated with focal cerebral dysfunction and is assumed to be increased closest to the location of dysfunction…”
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Mapping the structure-function relationship along macroscale gradients in the human brain by Collins, Evan, Chishti, Omar, Obaid, Sami, McGrath, Hari, King, Alex, Shen, Xilin, Arora, Jagriti, Papademetris, Xenophon, Constable, R. Todd, Spencer, Dennis D., Zaveri, Hitten P.

“…Functional coactivation between human brain regions is partly explained by white matter connections; however, how the structure-function relationship varies by…”
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High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter by McGrath, Hari, Zaveri, Hitten P., Collins, Evan, Jafar, Tamara, Chishti, Omar, Obaid, Sami, Ksendzovsky, Alexander, Wu, Kun, Papademetris, Xenophon, Spencer, Dennis D.

“…Precise cortical brain localization presents an important challenge in the literature. Brain atlases provide data-guided parcellation based on functional and…”
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A comparison of the power spectral density of scalp EEG and subjacent electrocorticograms by Petroff, Ognen A, Spencer, Dennis D, Goncharova, Irina I, Zaveri, Hitten P

“…Highlights • The power of the scalp EEG, in the canonical frequency bands, was between 6% and 15% of the power recorded by the subjacent ECoG. • A greater…”
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Expanding Brain-Computer Interfaces for Controlling Epilepsy Networks: Novel Thalamic Responsive Neurostimulation in Refractory Epilepsy by Gummadavelli, Abhijeet, Zaveri, Hitten P, Spencer, Dennis D, Gerrard, Jason L

“…Seizures have traditionally been considered hypersynchronous excitatory events and epilepsy has been separated into focal and generalized epilepsy based…”
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The relationship between seizures, interictal spikes and antiepileptic drugs by Goncharova, Irina I, Alkawadri, Rafeed, Gaspard, Nicolas, Duckrow, Robert B, Spencer, Dennis D, Hirsch, Lawrence J, Spencer, Susan S, Zaveri, Hitten P

“…Highlights • Interictal EEG spikes demonstrate a considerable diurnal variation with a night-time peak and day-time trough. • Spike rate decreases with AED…”
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Impaired consciousness in temporal lobe seizures: role of cortical slow activity by Englot, Dario J., Yang, Li, Hamid, Hamada, Danielson, Nathan, Bai, Xiaoxiao, Marfeo, Anthony, Yu, Lissa, Gordon, Aliza, Purcaro, Michael J., Motelow, Joshua E., Agarwal, Ravi, Ellens, Damien J., Golomb, Julie D., Shamy, Michel C. F., Zhang, Heping, Carlson, Chad, Doyle, Werner, Devinsky, Orrin, Vives, Kenneth, Spencer, Dennis D., Spencer, Susan S., Schevon, Catherine, Zaveri, Hitten P., Blumenfeld, Hal

“…Impaired consciousness requires altered cortical function. This can occur either directly from disorders that impair widespread bilateral regions of the cortex…”
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Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy by Sandhu, Mani Ratnesh S, Gruenbaum, Benjamin F, Gruenbaum, Shaun E, Dhaher, Roni, Deshpande, Ketaki, Funaro, Melissa C, Lee, Tih-Shih W, Zaveri, Hitten P, Eid, Tore

“…The enzyme glutamine synthetase (GS), also referred to as glutamate ammonia ligase, is abundant in astrocytes and catalyzes the conversion of ammonia and…”
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A Retrospective Analysis of Hippocampal Pathology in Human Temporal Lobe Epilepsy: Evidence for Distinctive Patient Subcategories by De Lanerolle, Nihal C., Kim, Jung H., Williamson, Anne, Spencer, Susan S., Zaveri, Hitten P., Eid, Toye, Spencer, Dennis D.

“…Purpose: This study is a retrospective analysis of the pathology of the hippocampus from patients with medically intractable temporal lobe epilepsy. We…”
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Seizure prediction — ready for a new era by Kuhlmann, Levin, Lehnertz, Klaus, Richardson, Mark P., Schelter, Björn, Zaveri, Hitten P.

“…Epilepsy is a common disorder characterized by recurrent seizures. An overwhelming majority of people with epilepsy regard the unpredictability of seizures as…”
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Modeling seizure networks in neuron-glia cultures using microelectrode arrays by Boddeti, Ujwal, Langbein, Jenna, McAfee, Darrian, Altshuler, Marcelle, Bachani, Muzna, Zaveri, Hitten P, Spencer, Dennis, Zaghloul, Kareem A, Ksendzovsky, Alexander

“…Epilepsy is a common neurological disorder, affecting over 65 million people worldwide. Unfortunately, despite resective surgery, over 30 of patients with…”
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Stability of infraslow correlation structure in time-shifted intracranial EEG signals by Joshi, Rasesh B, Duckrow, Robert B, Goncharova, Irina I, Hirsch, Lawrence J, Spencer, Dennis D, Godwin, Dwayne W, Zaveri, Hitten P

“…It is increasingly understood that the epilepsies are characterized by network pathology that can span multiple spatial and temporal scales. Recent work…”
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Artificial neural network trained on smartphone behavior can trace epileptiform activity in epilepsy by Duckrow, Robert B., Ceolini, Enea, Zaveri, Hitten P., Brooks, Cornell, Ghosh, Arko

“…A range of abnormal electrical activity patterns termed epileptiform discharges can occur in the brains of persons with epilepsy. These epileptiform discharges…”
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Evidence for astrocytes as a potential source of the glutamate excess in temporal lobe epilepsy by Perez, Edgar L, Lauritzen, Fredrik, Wang, Yue, Lee, Tih-Shih W, Kang, Dewey, Zaveri, Hitten P, Chaudhry, Farrukh A, Ottersen, Ole P, Bergersen, Linda H, Eid, Tore

“…Abstract Increased extracellular brain glutamate has been implicated in the pathophysiology of human refractory temporal lobe epilepsy (TLE), but the cause of…”
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Circadian-Like Rhythmicity of Extracellular Brain Glutamate in Epilepsy by Sandhu, Mani Ratnesh S., Dhaher, Roni, Gruenbaum, Shaun E., Raaisa, Raaisa, Spencer, Dennis D., Pavlova, Milena K., Zaveri, Hitten P., Eid, Tore

“…Seizures often exhibit striking circadian-like (~24-h) rhythms. While chronotherapy has shown promise in treating epilepsy, it is not widely used, in part…”
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Interictal spikes on intracranial recording: Behavior, physiology, and implications by Spencer, Susan S., Goncharova, Irina I., Duckrow, Robert B., Novotny, Edward J., Zaveri, Hitten P.

“…Summary Purpose:  The physiological, pathological, and clinical meaning of interictal spikes (IISs) remains controversial. We systematically analyzed the…”
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5-Aminovaleric acid suppresses the development of severe seizures in the methionine sulfoximine model of mesial temporal lobe epilepsy by Dhaher, Roni, Damisah, Eyiyemisi C, Wang, Helen, Gruenbaum, Shaun E, Ong, Caroline, Zaveri, Hitten P, Gruenbaum, Benjamin F, Eid, Tore

“…Abstract Mesial temporal lobe epilepsy (MTLE) is one of the most common forms of drug-resistant, localization-related epilepsies in humans. One potential…”
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Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy by Lauritzen, Fredrik, Perez, Edgar L, Melillo, Eric R, Roh, Jung-Min, Zaveri, Hitten P, Lee, Tih-Shih W, Wang, Yue, Bergersen, Linda H, Eid, Tore

“…Abstract Monocarboxylate transporter 1 (MCT1) facilitates the transport of monocarboxylate fuels (lactate, pyruvate and ketone bodies) and acidic drugs, such…”
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Altered network timing in the CA3-CA1 circuit of hippocampal slices from aged mice by Kanak, Daniel J, Rose, Gregory M, Zaveri, Hitten P, Patrylo, Peter R

“…Network patterns are believed to provide unique temporal contexts for coordinating neuronal activity within and across different regions of the brain. Some of…”
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