Search Results - "Zavacka, Kristyna"

Chromothripsis in Chronic Lymphocytic Leukemia: A Driving Force of Genome Instability by Zavacka, Kristyna, Plevova, Karla

“…Chromothripsis represents a mechanism of massive chromosome shattering and reassembly leading to the formation of derivative chromosomes with abnormal…”
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Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage by Mancikova, Veronika, Pesova, Michaela, Pavlova, Sarka, Helma, Robert, Zavacka, Kristyna, Hejret, Vaclav, Taus, Petr, Hynst, Jakub, Plevova, Karla, Malcikova, Jitka, Pospisilova, Sarka

“…TP53 gene abnormalities represent the most important biomarker in chronic lymphocytic leukemia (CLL). Altered protein modifications could also influence p53…”
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Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options by Malcikova, Jitka, Pavlova, Sarka, Kunt Vonkova, Barbara, Radova, Lenka, Plevova, Karla, Kotaskova, Jana, Pal, Karol, Dvorackova, Barbara, Zenatova, Marcela, Hynst, Jakub, Ondrouskova, Eva, Panovska, Anna, Brychtova, Yvona, Zavacka, Kristyna, Tichy, Boris, Tom, Nikola, Mayer, Jiri, Doubek, Michael, Pospisilova, Sarka

“…Patients with chronic lymphocytic leukemia (CLL) bearing TP53 mutations experience chemorefractory disease and are therefore candidates for targeted therapy…”
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Duplication of 8q24 in Chronic Lymphocytic Leukemia: Cytogenetic and Molecular Biologic Analysis of MYC Aberrations by Ondroušková, Eva, Bohúnová, Michaela, Závacká, Kristýna, Čech, Patrik, Šmuhařová, Petra, Boudný, Miroslav, Oršulová, Martina, Panovská, Anna, Radová, Lenka, Doubek, Michael, Plevová, Karla, Jarošová, Marie

“…Chronic lymphocytic leukemia (CLL) with cytogenetics findings, such as complex karyotype and deletions of TP53 or ATM , is associated with adverse clinical…”
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