Search Results - "Zaugg, Janine"
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Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators
Published in Phytochemistry (Oxford) (01-12-2013)“…By HPLC-based activity profiling, labdane diterpenoids from Curcuma kwangsiensis were identified as positive GABAA receptor modulators. A total of 11…”
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2
GABAA receptor modulation by piperine and a non-TRPV1 activating derivative
Published in Biochemical pharmacology (15-06-2013)“…The action of piperine (the pungent component of pepper) and its derivative SCT-66 ((2E,4E)-5-(1,3-benzodioxol-5-yl))-N,N-diisobutyl-2,4-pentadienamide) on…”
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3
HPLC-Based Activity Profiling for GABAA Receptor Modulators: A New Dihydroisocoumarin from Haloxylon scoparium
Published in Journal of natural products (Washington, D.C.) (23-04-2010)“…A new dihydroisocoumarin was isolated from a dichloromethane extract of Haloxylon scoparium with the aid of a functional assay with Xenopus oocytes transiently…”
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4
Abietane diterpenoids from Salvia sahendica--antiprotozoal activity and determination of their absolute configurations
Published in Planta medica (01-01-2013)“…In a screening of Iranian plants for antiprotozoal activity, an n-hexane extract of the roots of Salvia sahendica potently inhibited the growth of Plasmodium…”
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5
HPLC-Based Activity Profiling: Discovery of Piperine as a Positive GABAA Receptor Modulator Targeting a Benzodiazepine-Independent Binding Site
Published in Journal of natural products (Washington, D.C.) (26-02-2010)“…A plant extract library was screened for GABAA receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl…”
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6
HPLC-based activity profiling: discovery of piperine as a positive GABA(A) receptor modulator targeting a benzodiazepine-independent binding site
Published in Journal of natural products (Washington, D.C.) (26-02-2010)“…A plant extract library was screened for GABA(A) receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl…”
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7
HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium
Published in Journal of natural products (Washington, D.C.) (23-04-2010)“…A new dihydroisocoumarin was isolated from a dichloromethane extract of Haloxylon scoparium with the aid of a functional assay with Xenopus oocytes transiently…”
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8
Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling
Published in Journal of natural products (Washington, D.C.) (24-06-2011)“…In a two-microelectrode voltage clamp with Xenopus laevis oocytes, a petroleum ether extract of Acorus calamus rhizomes enhanced the GABA-induced chloride…”
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9
Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations
Published in Phytochemistry (Oxford) (01-12-2011)“…Thirteen positive GABA A receptor modulators were identified in Kadsura longipedunculata by HPLC-based activity profiling using a Xenopus oocyte assay…”
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10
Positive GABAA Receptor Modulators from Acorus calamus and Structural Analysis of (+)-Dioxosarcoguaiacol by 1D and 2D NMR and Molecular Modeling
Published in Journal of natural products (Washington, D.C.) (24-06-2011)“…In a two-microelectrode voltage clamp with Xenopus laevis oocytes, a petroleum ether extract of Acorus calamus rhizomes enhanced the GABA-induced chloride…”
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11
Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice
Published in Journal of natural products (Washington, D.C.) (26-08-2011)“…An ethyl acetate extract of Biota orientalis leaves potentiated GABA-induced control current by 92.6% ± 22.5% when tested at 100 μg/mL in Xenopus laevis…”
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12
Discovery of GABA(A) receptor modulator aristolactone in a commercial sample of the Chinese herbal drug "Chaihu" (Bupleurum chinense roots) unravels adulteration by nephrotoxic Aristolochia manshuriensis roots
Published in Planta medica (01-02-2012)“…In a two-microelectrode voltage clamp assay using Xenopus laevis oocytes, a petroleum ether extract prepared from a commercial sample of the traditional…”
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13
Identification and Characterization of GABAA Receptor Modulatory Diterpenes from Biota orientalis That Decrease Locomotor Activity in Mice
Published in Journal of natural products (Washington, D.C.) (26-08-2011)“…An ethyl acetate extract of Biota orientalis leaves potentiated GABA-induced control current by 92.6% ± 22.5% when tested at 100 μg/mL in Xenopus laevis…”
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14
HPLC-based activity profiling--discovery of sanggenons as GABAA receptor modulators in the traditional Chinese drug Sang bai pi (Morus alba root bark)
Published in Planta medica (01-03-2012)“…EtOAc extracts from two batches of Morus alba root bark (Sang bai pi) potentiated γ-aminobutyric acid (GABA)-induced chloride influx in Xenopus oocytes, which…”
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15
Quantitative Analysis of Anti-inflammatory and Radical Scavenging Triterpenoid Esters in Evening Primrose Seeds
Published in Journal of agricultural and food chemistry (06-09-2006)“…Lipophilic triterpenoidal esters with radical scavenging and cyclooxygenase inhibitory properties were recently found in cold-pressed, nonraffinated evening…”
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HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes
Published in Fitoterapia (01-04-2011)“…A petroleum ether extract of the traditional Chinese herbal drug Duhuo (roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan), showed significant…”
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HPLC-based activity profiling of Angelica pubescens roots for new positive GABA A receptor modulators in Xenopus oocytes
Published in Fitoterapia (01-04-2011)“…A petroleum ether extract of the traditional Chinese herbal drug Duhuo (roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan), showed significant…”
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18
HPLC-based activity profiling of Angelica pubescens roots for new positive GABA sub(A)receptor modulators in Xenopus oocytes
Published in Fitoterapia (01-04-2011)“…A petroleum ether extract of the traditional Chinese herbal drug Duhuo (roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan), showed significant…”
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19
HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes
Published in Fitoterapia (01-04-2011)“…A petroleum ether extract of the traditional Chinese herbal drug Duhuo (roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan), showed significant…”
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